Search Results - "YEKUTIELI, Daniel"

Hierarchical False Discovery Rate-Controlling Methodology by Yekutieli, Daniel

“…We discuss methodology for controlling the false discovery rate (FDR) in complex large-scale studies that involve testing multiple families of hypotheses; the…”
Get full text

Quantitative trait Loci analysis using the false discovery rate by Benjamini, Yoav, Yekutieli, Daniel

“…False discovery rate control has become an essential tool in any study that has a very large multiplicity problem. False discovery rate-controlling procedures…”
Get full text

The Control of the False Discovery Rate in Multiple Testing under Dependency by Benjamini, Yoav, Yekutieli, Daniel

“…Benjamini and Hochberg suggest that the false discovery rate may be the appropriate error rate to control in many applied multiple testing problems. A simple…”
Get full text

Extracting replicable associations across multiple studies: Empirical Bayes algorithms for controlling the false discovery rate by Amar, David, Shamir, Ron, Yekutieli, Daniel

“…In almost every field in genomics, large-scale biomedical datasets are used to report associations. Extracting associations that recur across multiple studies…”
Get full text

Selective inference in complex research by Benjamini, Yoav, Heller, Ruth, Yekutieli, Daniel

“…We explain the problem of selective inference in complex research using a recently published study: a replicability study of the associations in order to…”
Get full text

False Discovery Rate-Adjusted Multiple Confidence Intervals for Selected Parameters by Benjamini, Yoav, Yekutieli, Daniel

“…Often in applied research, confidence intervals (CIs) are constructed or reported only for parameters selected after viewing the data. We show that such…”
Get full text

Computational characterization of B-cell epitopes by Rubinstein, Nimrod D., Mayrose, Itay, Halperin, Dan, Yekutieli, Daniel, Gershoni, Jonathan M., Pupko, Tal

“…Characterizing B-cell epitopes is a fundamental step for understanding the immunological basis of bio-recognition. To date, epitope analyses have either been…”
Get full text

Resampling-based false discovery rate controlling multiple test procedures for correlated test statistics by Yekutieli, Daniel, Benjamini, Yoav

“…A new false discovery rate controlling procedure is proposed for multiple hypotheses testing. The procedure makes use of resampling-based p-value adjustment,…”
Get full text

The accuracy of Gram stain of respiratory specimens in excluding Staphylococcus aureus in ventilator-associated pneumonia by Gottesman, Tamar, MD, Yossepowitch, Orit, MD, Lerner, Evgenia, Schwartz-Harari, Orna, MSc, Soroksky, Arie, MD, Yekutieli, Daniel, PhD, Dan, Michael, MD

“…Abstract Objective To evaluate the Gram stain of deep tracheal aspirate as a tool to direct empiric antibiotic therapy, and more specifically as a tool to…”
Get full text

Adjusted Bayesian inference for selected parameters by Yekutieli, Daniel

“…We address the problem of providing inference from a Bayesian perspective for parameters selected after viewing the data. We present a Bayesian framework for…”
Get full text

Indications for aggravation in summer heat conditions over the Mediterranean Basin by Ziv, Baruch, Saaroni, Hadas, Baharad, Anat, Yekutieli, Daniel, Alpert, Pinhas

“…The summer temperature variations over the Mediterranean Basin were studied through the 850 hPa level for the months June–August along the period 1948–2003,…”
Get full text

Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression by Chamovitz, Daniel A, Oron, Efrat, Tuller, Tamir, Li, Ling, Rozovsky, Nina, Yekutieli, Daniel, Rencus-Lazar, Sigal, Segal, Daniel, Chor, Benny, Edgar, Bruce A

“…The COP9 signalosome (CSN), an eight‐subunit protein complex, is conserved in all higher eukaryotes. CSN intersects the ubiquitin–proteasome pathway,…”
Get full text

SELECTIVE SIGN-DETERMINING MULTIPLE CONFIDENCE INTERVALS WITH FCR CONTROL by Weinstein, Asaf, Yekutieli, Daniel

“…Given m unknown parameters with corresponding independent estimators, the Benjamini–Hochberg (BH) procedure can be used to classify the signs of the…”
Get full text

Adaptive linear step-up procedures that control the false discovery rate by Benjamini, Yoav, Krieger, Abba M., Yekutieli, Daniel

“…The linear step-up multiple testing procedure controls the false discovery rate at the desired level q for independent and positively dependent test…”
Get full text

Bayesian tests for composite alternative hypotheses in cross-tabulated data by Yekutieli, Daniel

“…We present a methodology for constructing significance tests for “difficult” composite alternative hypotheses that have no natural test statistic. We apply our…”
Get full text

Identifying differentially expressed genes usingfalse discovery rate controlling procedures by Reiner, Anat, Yekutieli, Daniel, Benjamini, Yoav

“…Motivation: DNA microarrays have recently been used for the purpose of monitoring expression levels of thousands of genes simultaneously and identifying those…”
Get full text

Identifying differentially expressed genes using false discovery rate controlling procedures by REINER, Anat, YEKUTIELI, Daniel, BENJAMINI, Yoav

“…DNA microarrays have recently been used for the purpose of monitoring expression levels of thousands of genes simultaneously and identifying those genes that…”
Get full text

REPLICABILITY ANALYSIS FOR GENOME-WIDE ASSOCIATION STUDIES by Heller, Ruth, Yekutieli, Daniel

“…The paramount importance of replicating associations is well recognized in the genome-wide associaton (GWA) research community, yet methods for assessing…”
Get full text

Cluster-based analysis of FMRI data by Heller, Ruth, Stanley, Damian, Yekutieli, Daniel, Rubin, Nava, Benjamini, Yoav

“…We propose a method for the statistical analysis of fMRI data that tests cluster units rather than voxel units for activation. The advantages of this analysis…”
Get full text

repfdr: a tool for replicability analysis for genome-wide association studies by Heller, Ruth, Yaacoby, Shay, Yekutieli, Daniel

“…Identification of single nucleotide polymorphisms that are associated with a phenotype in more than one study is of great scientific interest in the…”
Get full text