Search Results - "YEI-MEI PENG"

Breast Tissue Accumulation of Retinamides in a Randomized Short-term Study of Fenretinide by SABICHI, Anita L, MODIANO, Manual R, LEE, J. Jack, PENG, Yei-Mei, XU, Ming-Jing, VILLAR, Hugo, DALTON, William S, LIPPMAN, Scott M

“…Purpose: The synthetic retinoid N -(4-hydroxyphenyl)retinamide [4-HPR (or fenretinide)] has preclinical and clinical preventive activity in breast…”
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Concentrations and plasma-tissue-diet relationships of carotenoids, retinoids, and tocopherols in humans by Peng, Y M, Peng, Y S, Lin, Y, Moon, T, Roe, D J, Ritenbaugh, C

“…Micronutrients, such as beta-carotene and vitamins A and E, are potential chemopreventive agents; however, their concentrations in human target tissues are…”
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Importance of the form of topical vitamin E for prevention of photocarcinogenesis by Gensler, H L, Aickin, M, Peng, Y M, Xu, M

“…With increasing solar ultraviolet (UV)-B radiation reaching the Earth's surface and the incidence of skin cancer rising steadily, there is an ever-increasing…”
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Disposition and metabolism of topically administered alpha-tocopherol acetate: a common ingredient of commercially available sunscreens and cosmetics by Alberts, D S, Goldman, R, Xu, M J, Dorr, R T, Quinn, J, Welch, K, Guillen-Rodriguez, J, Aickin, M, Peng, Y M, Loescher, L, Gensler, H

“…Skin cancers are a serious health problem in the United States. One common method of skin cancer primary prevention is use of sunscreens. Research has been…”
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Exhaled ethane and antioxidant vitamin supplements in active smokers by Do, B K, Garewal, H S, Clements, Jr, N C, Peng, Y M, Habib, M P

“…To determine the effect of nutritional agents on lipid peroxidation, 10 smokers were given 6 mg beta carotene, 200 IU vitamin E, and 250 mg vitamin C 4 times…”
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Carotenoids, tocopherols, and retinoids in human buccal mucosal cells: intra- and interindividual variability and storage stability by Peng, YS, Peng, YM, McGee, DL, Alberts, DS

“…The baseline, intra-, and interindividual variability as well as storage stability of carotenoids, tocopherols, and retinoids in human buccal mucosal cells…”
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A Randomized, Double Blind, Phase III Trial Using Oral β-Carotene Supplementation for Women with High-Grade Cervical Intraepithelial Neoplasia by Kristin A. Keefe, Michael J. Schell, Cheryl Brewer, Michael McHale, Wendy Brewster, Julia A. Chapman, G. Scott Rose, D. Scott McMeeken, Westley Lagerberg, Yei-Mei Peng, Sharon P. Wilczynski, Hoda Anton-Culver, Frank L. Meyskens, Michael L. Berman

“…To evaluate the effect of daily β-carotene (30 mg) versus placebo over a 2-year period on cervical intraepithelial neoplasia (CIN) 2 and 3 lesions. Human…”
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Phase I clinical and pharmacokinetic study of mitoxantrone given to patients by intraperitoneal administration by ALBERTS, D. S, SURWIT, E. A, YEI-MEI PENG, RIVEST, R, GRAHAM, V, MCDONALD, L, ROE, D

“…On the basis of its high degree of cytotoxicity against fresh human ovarian cancers and its relative lack of vesicant activity, mitoxantrone administered by…”
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Chemoprevention of Human Actinic Keratoses by Topical 2-(Difluoromethyl)-dl-ornithine by ALBERTS, David S, DORR, Robert T, SALASCHE, Stuart, ROE, Denise J, BOWDEN, G. Timothy, EINSPAHR, Janine G, AICKIN, Mikel, SABODA, Kathylynn, MIN JIAN XU, PENG, Yei-Mei, GOLDMAN, Rayna, FOOTE, Janet A, WARNEKE, James A

“…α-2-(Difluoromethyl)-dl-ornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, has been shown to suppress skin carcinogenesis in murine models…”
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Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous versus oral administration in a randomized, crossover trial by STRUCK, R. F, ALBERTS, D. S, HORNE, K, PHILLIPS, J. G, YEI-MEI PENG, ROE, D. J

“…Since cyclophosphamide is used by both oral and i.v. routes in the treatment of hematological and solid malignancies, we designed a randomized, crossover…”
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Pharmacokinetics of N-4-hydroxyphenyl-retinamide and the effect of its oral administration on plasma retinol concentrations in cancer patients by Peng, Y M, Dalton, W S, Alberts, D S, Xu, M J, Lim, H, Meyskens, Jr, F L

“…Concurrent with a phase-II trial of 4HPR in patients with various cancers, we studied the plasma pharmacokinetics of both 4HPR and its major metabolite 4MPR as…”
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A clinical and pharmacokinetic study of isolated limb perfusion with heat and melphalan for melanoma by Minor, D R, Allen, R E, Alberts, D, Peng, Y M, Tardelli, G, Hutchinson, J

“…The pharmacokinetics of isolated limb perfusion were studied to see what melphalan concentrations were achieved and how effective the isolation was…”
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Comparative molecular pharmacology in leukemic L1210 cells of the anthracene anticancer drugs mitoxantrone and bisantrene by BOWDEN, G. T, ROBERTS, R, ALBERTS, D. S, YEI-MEI PENG, GARCIA, D

“…1,4-Dihydroxy-5,8-bis(2-[(2-hydroxyethyl)aminoethyl]amino)-9, 10-anthracenedione (mitoxantrone) and 9,10-anthracenedicarboxaldehyde…”
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Disposition of mitoxantrone in cancer patients by ALBERTS, D. S, YEI-MEI PENG, LEIGH, S, DAVIS, T. P, WOODWARD, D. L

“…We have used a highly sensitive high-performance liquid chromatographic assay to evaluate the pharmacokinetics and tissue disposition of mitoxantrone, an…”
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Evidence for persistence of mitoxantrone within the peritoneal cavity following intraperitoneal delivery by Markman, M, Alberts, D, Rubin, S, Hakes, T, Lewis, Jr, J L, Reichman, B, Jones, W, Curtin, J, Barakat, R, Brodar, F

“…In clinical trials examining the intraperitoneal (ip) administration of mitoxantrone as therapy of platinum-refractory small-volume residual ovarian cancer,…”
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13-cis-Retinoic Acid or All-trans-Retinoic Acid plus Interferon-α in Recurrent Cervical Cancer: A Southwest Oncology Group Phase II Randomized Trial by Weiss, Geoffrey R., Liu, P.Y., Alberts, David S., Peng, Yei-Mei, Fisher, Emily, Xu, Min Jian, Scudder, Sidney A., Baker, Laurence H., Moore, Dennis F., Lippman, Scott M.

“…Purpose.Preclinical and clinical data support the study of retinoids and interferon-α (IFN-α) in advanced squamous cell carcinoma of the uterine cervix (SCC)…”
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Effect of dipyridamole on fluorodeoxyuridine cytotoxicity in vitro and in cancer patients by BUZAID, A. C, ALBERTS, D. S, EINSPAHR, J, MOSLEY, K, YEI-MEI PENG, TUTSCH, K, SPEARS, C. P, GAREWAL, H. S

“…Dipyridamole (DP) has previously been studied both in vitro and in vivo in combination with various anti-metabolites, including methotrexate and 5-fluorouracil…”
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High-performance liquid chromatography of the provitamin A beta-carotene in plasma by Peng, Y M, Beaudry, J, Alberts, D S, Davis, T P

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Influence of serum and tissue micronutrient levels on the regression of untreated cervical intraepithelial neoplasia 2 and 3 by McHale, Michael T, Berman, Michael L, Keefe, Kristin A, Schell, Michael J, Peng, Yei-Mei, Monk, Bradley J

“…OBJECTIVE.: To determine the influence of micronutrient levels on the regression of untreated cervical intraepithelial neoplasia (CIN). MATERIALS AND METHODS.:…”
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A phase I trial of AUC-directed carboplatin with infusional doxorubicin and ifosfamide plus G-CSF in patients with advanced gynecologic malignancies by LOPEZ, Ana Maria, KETCHUM, Marsha, NICHOLS, Heather, XU, Min-Jian, PENG, Yei-Mei, DORR, Robert, ALBERTS, David S

“…The effect of the addition of G-CSF to carboplatin, ifosfamide and doxorubicin (CIA) at the maximally tolerated dose (MTD) was studied in a phase I clinical…”
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