Search Results - "YAYAMA, Katsutoshi"

Protein Tyrosine Phosphatase Inhibitor, Orthovanadate, Induces Contraction via Rho Kinase Activation in Mouse Thoracic Aortas by Terada, Yuka, Higashi, Naoki, Hidaka, Yuki, Isomoto, Yasumasa, Yayama, Katsutoshi

“…Orthovanadate (OVA), a protein tyrosine phosphatase inhibitor, induces contraction in endothelium-denuded mouse thoracic aortas. OVA-induced contraction was…”
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Angiotensin II-Induced Vasoconstriction via Rho Kinase Activation in Pressure-Overloaded Rat Thoracic Aortas by Terada, Yuka, Yayama, Katsutoshi

“…Angiotensin II (Ang II) induces vasoconstriction through myosin light chain (MLC) kinase activation and MLC phosphatase inactivation via phosphorylation of…”
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Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase by Ito, Kazuya, Matsuzaki, Mai, Sasahara, Tomoya, Shin, Mariko, Yayama, Katsutoshi

“…Orthovanadate (OVA), a protein tyrosine phosphatase inhibitor, induces vasoconstriction in a Rho kinase-dependent manner. The aim of this study was to…”
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p38 Mitogen-Activated Protein Kinase Mediates Hyperosmolarity-Induced Vasoconstriction through Myosin Light Chain Phosphorylation and Actin Polymerization in Rat Aorta by Sasahara, Tomoya, Yayama, Katsutoshi, Okamoto, Hiroshi

“…Hyperosmotic stress induces the contractile response of vascular smooth muscle cells (VSMCs). Previous studies have demonstrated that cytoskeleton…”
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Epidermal growth factor induces Ca2+ sensitization through Rho-kinase-dependent phosphorylation of myosin phosphatase target subunit 1 in vascular smooth muscle by Sasahara, Tomoya, Okamoto, Hiroshi, Ohkura, Natsumi, Kobe, Asami, Yayama, Katsutoshi

“…We previously found that the protein tyrosine phosphatase inhibitor orthovanadate evoked a vasoconstrictor effect in rat aortas via Rho-kinase-dependent…”
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Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice by Tsujikawa, Kazutake, Yayama, Katsutoshi, Hayashi, Tamon, Matsushita, Hiroaki, Yamaguchi, Taijiro, Shigeno, Tomomi, Ogitani, Yusuke, Hirayama, Megumi, Kato, Tetsuya, Fukada, So-ichiro, Takatori, Shingo, Kawasaki, Hiromu, Okamoto, Hiroshi, Ikawa, Masahito, Okabe, Masaru, Yamamoto, Hiroshi

“…Calcitonin gene-related peptide (CGRP) is thought to be a prominent neuropeptide in cardiovascular regulation and neuroimmune modulation. There are two…”
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Na+ /H+ exchanger inhibitor induces vasorelaxation through nitric oxide production in endothelial cells via intracellular acidification-associated Ca2+ mobilization by Sasahara, Tomoya, Yayama, Katsutoshi, Matsuzaki, Toshihiro, Tsutsui, Masato, Okamoto, Hiroshi

“…Abstract The objective of this study was to determine the mechanism by which Na+ /H+ exchanger (NHE) inhibitors induce vasodilatation. The NHE inhibitors, 5-(…”
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Short-term changes in intracellular ROS localisation after the silver nanoparticles exposure depending on particle size by Onodera, Akira, Nishiumi, Fumiko, Kakiguchi, Kisa, Tanaka, Atsushi, Tanabe, Nami, Honma, Aki, Yayama, Katsutoshi, Yoshioka, Yasuo, Nakahira, Kumiko, Yonemura, Shigenobu, Yanagihara, Itaru, Tsutsumi, Yasuo, Kawai, Yuichi

“…Silver nanoparticles (AgNPs) induce the production of reactive oxygen species (ROS) and apoptosis. These effects are enhanced by smaller particles. Using…”
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Amorphous nanosilica particles evoke vascular relaxation through PI3K/Akt/eNOS signaling by Onodera, Akira, Yayama, Katsutoshi, Tanaka, Atsushi, Morosawa, Hideto, Furuta, Takuya, Takeda, Naoya, Kakiguchi, Kisa, Yonemura, Shigenobu, Yanagihara, Itaru, Tsutsumi, Yasuo, Kawai, Yuichi

“…There have been several reported studies on the distribution and/or toxicity of nanosilica particles. However, the influence of these particles on blood…”
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Angiotensin-Converting Enzyme Inhibitor Enhances Liver Regeneration Following Partial Hepatectomy: Involvement of Bradykinin B2 and Angiotensin AT1 Receptors by Yayama, Katsutoshi, Sugiyama, Kaori, Miyagi, Ryoko, Okamoto, Hiroshi

“…Angiotensin-converting enzyme (ACE) inhibitor enhances the liver regeneration in rats after partial hepatectomy (PH), though the precise mechanisms are…”
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Reduction of calcium flux from the extracellular region and endoplasmic reticulum by amorphous nano-silica particles owing to carboxy group addition on their surface by Onodera, Akira, Yayama, Katsutoshi, Morosawa, Hideto, Ishii, Yukina, Tsutsumi, Yasuo, Kawai, Yuichi

“…Several studies have reported that amorphous nano-silica particles (nano-SPs) modulate calcium flux, although the mechanism remains incompletely understood. We…”
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Orthovanadate‐induced vasocontraction is mediated by the activation of Rho‐kinase through Src‐dependent transactivation of epidermal growth factor receptor by Yayama, Katsutoshi, Sasahara, Tomoya, Ohba, Hisaaki, Funasaka, Ayaka, Okamoto, Hiroshi

“…Orthovanadate (OVA), a protein tyrosine phosphatase (PTPase) inhibitor, exerts contractile effects on smooth muscle in a Rho‐kinase‐dependent manner, but the…”
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Angiotensin II Regulates Liver Regeneration via Type 1 Receptor Following Partial Hepatectomy in Mice by Yayama, Katsutoshi, Miyagi, Ryoko, Sugiyama, Kaori, Sugaya, Takeshi, Fukamizu, Akiyoshi, Okamoto, Hiroshi

“…Angiotensin II (Ang II) is an important mediator stimulating liver fibrosis after liver injury. However, it is not known whether Ang II plays a role in liver…”
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Up-regulation of angiotensin II type 2 receptor in rat thoracic aorta by pressure-overload by Yayama, Katsutoshi, Horii, Miyuki, Hiyoshi, Hiromi, Takano, Masaoki, Okamoto, Hiroshi, Kagota, Satomi, Kunitomo, Masaru

“…We have examined whether expression of angiotensin II (Ang II) type 1 (AT(1)) and/or type 2 (AT(2)) receptors are changed in thoracic aorta under…”
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Abstract P2017: Angiotensin-Induced Constriction via Rho Kinase Activation in Pressure-Overloaded Rat Thoracic Aortas by Terada, Yuka, Yayama, Katsutoshi

“…Abstract only Activation of the angiotensin II (Ang II) receptor increases myosin light chain (MLC) kinase activity and causes inactivation of MLC phosphatase…”
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Lipopolysaccharide activates the kallikrein–kinin system in mouse choroid plexus cell line ECPC4 by Takano, Masaoki, Satoh, Chieko, Kunimatsu, Naomi, Otani, Mieko, Hamada-Kanazawa, Michiko, Miyake, Masaharu, Ming, KyongSong, Yayama, Katsutoshi, Okamoto, Hiroshi

“…Regulation of the kallikrein–kinin system in cerebral inflammation is still unclear. Here, we used reverse-transcription polymerase chain reaction (RT-PCR)…”
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Kallikrein Gene Delivery Attenuates Hypertension and Cardiac Hypertrophy and Enhances Renal Function in Goldblatt Hypertensive Rats by Yayama, Katsutoshi, Wang, Cindy, Chao, Lee, Chao, Julie

“…To demonstrate potential therapeutic effects of kallikrein gene delivery, we delivered adenovirus (Ad.CMV-cHK) carrying the human tissue kallikrein gene into…”
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The Lipopolysaccharide-Induced Up-Regulation of Bradykinin B2-Receptor in the Mouse Heart Is Mediated by Tumor Necrosis Factor-α and Angiotensin II by Yayama, Katsutoshi, Hiyoshi, Hiromi, Sugiyama, Kaori, Okamoto, Hiroshi

“…Our present study aimed to characterize the effects of lipopolysaccharide (LPS) on the expression of the bradykinin B2-receptor in the mouse heart, which may…”
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Angiotensin II-induced vasodilation via type 2 receptor: Role of bradykinin and nitric oxide by Yayama, Katsutoshi, Okamoto, Hiroshi

“…Angiotensin II (Ang II) plays important roles in the regulation of cardiovascular functions and diseases mainly via the type 1 (AT1) receptor. In contrast,…”
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Expressions of Bradykinin B2-Receptor, Kallikrein and Kininogen mRNAs in the Heart Are Altered in Pressure-Overload Cardiac Hypertrophy in Mice by YAYAMA, Katsutoshi, HIYOSHI, Hiromi, OKAMOTO, Hiroshi

“…Angiotensin-converting enzyme inhibitors prevent cardiac hypertrophy in vivo, and a component of this ameliorative effect has been attributed to accumulation…”
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