Search Results - "YATHAM, L. N"

A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials of ketamine in the rapid treatment of major depressive episodes by McGirr, A, Berlim, M T, Bond, D J, Fleck, M P, Yatham, L N, Lam, R W

“…There is growing interest in glutamatergic agents in depression, particularly ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist. We aimed…”
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Neuropsychological functioning in euthymic bipolar disorder: a meta-analysis by Torres, I. J., Boudreau, V. G., Yatham, L. N.

“…Objective:  Although cognitive deficits are prominent in symptomatic patients with bipolar disorder, the extent and pattern of cognitive impairment in euthymic…”
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Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force by Miskowiak, KW, Burdick, KE, Martinez‐Aran, A, Bonnin, CM, Bowie, CR, Carvalho, AF, Gallagher, P, Lafer, B, López‐Jaramillo, C, Sumiyoshi, T, McIntyre, RS, Schaffer, A, Porter, RJ, Torres, IJ, Yatham, LN, Young, AH, Kessing, LV, Vieta, E

“…Objectives To aid the development of treatment for cognitive impairment in bipolar disorder, the International Society for Bipolar Disorders (ISBD) convened a…”
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Assessing and addressing cognitive impairment in bipolar disorder: the International Society for Bipolar Disorders Targeting Cognition Task Force recommendations for clinicians by Miskowiak, KW, Burdick, KE, Martinez‐Aran, A, Bonnin, CM, Bowie, CR, Carvalho, AF, Gallagher, P, Lafer, B, López‐Jaramillo, C, Sumiyoshi, T, McIntyre, RS, Schaffer, A, Porter, RJ, Purdon, S, Torres, IJ, Yatham, LN, Young, AH, Kessing, LV, Vieta, E

“…Objectives Cognition is a new treatment target to aid functional recovery and enhance quality of life for patients with bipolar disorder. The International…”
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Relationship between cognitive functioning and 6-month clinical and functional outcome in patients with first manic episode bipolar I disorder by Torres, I J, DeFreitas, C M, DeFreitas, V G, Bond, D J, Kunz, M, Honer, W G, Lam, R W, Yatham, L N

“…Although cognitive deficits in bipolar disorder have been associated with diminished functional outcome, this relationship has been studied primarily through…”
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Lower cognitive functioning as a predictor of weight gain in bipolar disorder: a 12‐month study by Bond, D. J., Torres, I. J., Lee, S. S., Kozicky, J.‐M., Silveira, L. E., Dhanoa, T., Lam, R. W., Yatham, L. N.

“…Objective In cross‐sectional studies, elevated body mass index (BMI) is associated with cognitive impairment in bipolar disorder (BD). We investigated the…”
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A systematic review of interventions in the early course of bipolar disorder I or II: a report of the International Society for Bipolar Disorders Taskforce on early intervention by Ratheesh, A., Hett, D., Ramain, J., Wong, E., Berk, L., Conus, P., Fristad, M. A., Goldstein, T., Hillegers, M., Jauhar, S., Kessing, L. V., Miklowitz, D. J., Murray, G., Scott, J., Tohen, M., Yatham, L. N., Young, A. H., Berk, M., Marwaha, S.

“…Background Given the likelihood of progressive illness in bipolar disorder (BD), it is important to understand the benefits and risks of interventions…”
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Decreased mRNA expression of uncoupling protein 2, a mitochondrial proton transporter, in post-mortem prefrontal cortex from patients with bipolar disorder and schizophrenia by Gigante, A.D., Andreazza, A.C., Lafer, B., Yatham, L.N., Beasley, C.L., Young, L.T.

“…► Oxidative stress is associated with bipolar disorder (BD) and schizophrenia (SCZ). ► Uncoupling protein 2 (UCP2) is a proton carrier located in the…”
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The impact of childhood trauma on cognitive functioning in patients recently recovered from a first manic episode: Data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM) by Bücker, J, Kozicky, J, Torres, I.J, Kauer-Sant’anna, M, Silveira, L.E, Bond, D.J, Lam, R.W, Yatham, L.N

“…Abstract Background: Both bipolar disorder (BD) and childhood trauma are associated with cognitive impairment. People with BD have high rates of childhood…”
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Childhood maltreatment and corpus callosum volume in recently diagnosed patients with bipolar I disorder: Data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM) by Bücker, J, Muralidharan, K, Torres, I.J, Su, W, Kozicky, J, Silveira, L.E, Bond, D.J, Honer, W.G, Kauer-Sant'Anna, M, Lam, R.W, Yatham, L.N

“…Abstract Childhood trauma (CT) has been associated with abnormalities in the corpus callosum (CC). Decreased CC volumes have been reported in children and…”
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Three‐year longitudinal cognitive functioning in patients recently diagnosed with bipolar disorder by Torres, I. J., Qian, H., Basivireddy, J., Chakrabarty, T., Wong, H., Lam, R. W., Yatham, L. N.

“…Objective The longitudinal course of neuropsychological functioning after the first manic episode in bipolar disorder is unknown. The present study evaluated…”
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Acute and maintenance treatment of bipolar mania: the role of atypical antipsychotics by Yatham, Lakshmi N

“…:  Bipolar disorder is a complex condition including depression, mania, and in many cases associated with comorbid anxiety symptoms and substance abuse. Mood…”
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Psychometric properties of the well-being index (WHO-5) spanish version in a sample of euthymic patients with bipolar disorder by Bonnín, C.M., Yatham, L.N., Michalak, E.E., Martínez-Arán, A., Dhanoa, T., Torres, I., Santos-Pascual, C., Valls, E., Carvalho, A.F., Sánchez-Moreno, J., Valentí, M., Grande, I., Hidalgo-Mazzei, D., Vieta, E., Reinares, M.

“…The concept of well-being which focuses on positive emotions has received increased research attention. However, a consensus definition of this term is…”
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Optimal duration of risperidone or olanzapine adjunctive therapy to mood stabilizer following remission of a manic episode: A CANMAT randomized double-blind trial by Yatham, L N, Beaulieu, S, Schaffer, A, Kauer-Sant'Anna, M, Kapczinski, F, Lafer, B, Sharma, V, Parikh, S V, Daigneault, A, Qian, H, Bond, D J, Silverstone, P H, Walji, N, Milev, R, Baruch, P, da Cunha, A, Quevedo, J, Dias, R, Kunz, M, Young, L T, Lam, R W, Wong, H

“…Atypical antipsychotic adjunctive therapy to lithium or valproate is effective in treating acute mania. Although continuation of atypical antipsychotic…”
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An open study of lamotrigine in refractory bipolar depression by Kusumakar, Vivek, Yatham, Lakshmi N

“…Bipolar depressed patients ( n=22) who were refractory to treatment with a combination of divalproex sodium (DVP) and another mood stabilizer or DVP and an…”
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Lamotrigine treatment of rapid cycling bipolar disorder by Kusumakar, V, Yatham, L N

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Brain-derived neurotrophic factor and inflammatory markers in school-aged children with early trauma by Bücker, J., Fries, G. R., Kapczinski, F., Post, R. M., Yatham, L. N., Vianna, P., Bogo Chies, J. A., Gama, C. S., Magalhães, P. V., Aguiar, B. W., Pfaffenseller, B., Kauer-Sant'Anna, M.

“…Objective The impact of childhood trauma (CT) on brain‐derived neurotrophic factor (BDNF) and cytokines levels remains unclear. We investigated the association…”
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Bipolaroids: functional imaging in bipolar disorder by Malhi, G. S., Lagopoulos, J., Owen, A. M., Yatham, L. N.

“…Objective:  To evaluate the literature pertaining to the use of functional magnetic resonance imaging (fMRI) in bipolar disorder research. Method:  A search…”
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Comparative efficacy of Typical and atypical antipsychotics as add-on therapy to mood stabilizers in the treatment of acute mania by MILLER, Debra S, YATHAM, Lakshmi N, LAM, Raymond W

“…Typical antipsychotics are commonly used in combination with mood stabilizers for acute mania. Although typical antipsychotics are effective, they have…”
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Neuroendocrine probes of serotonergic function: a critical review by Yatham, L N, Steiner, M

“…Neuroendocrine probes of serotonergic function are based on the premise that serotonin (5-HT) exhibits an excitory influence on the release of certain anterior…”
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