Search Results - "YASUTOMO, Koji"

Genetics and animal models of familial pulmonary fibrosis by Yasutomo, Koji

“…Abstract Pulmonary fibrosis is caused by the interplay between genetic and environmental factors. Recent studies have revealed various genes associated with…”
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Dysregulation of immunoproteasomes in autoinflammatory syndromes by Yasutomo, Koji

“…Abstract Immunoproteasomes degrade ubiquitin-coupled proteins and play a role in creating peptides for presentation by MHC class I proteins. Studies of…”
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An inherited mutation in NLRC4 causes autoinflammation in human and mice by Kitamura, Akiko, Sasaki, Yuki, Abe, Takaya, Kano, Hirotsugu, Yasutomo, Koji

“…Autoinflammatory syndromes cause sterile inflammation in the absence of any signs of autoimmune responses. Familial cold autoinflammatory syndrome (FCAS) is…”
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Quantitative evaluation of SARS-CoV-2 inactivation using a deep ultraviolet light-emitting diode by Minamikawa, Takeo, Koma, Takaaki, Suzuki, Akihiro, Mizuno, Takahiko, Nagamatsu, Kentaro, Arimochi, Hideki, Tsuchiya, Koichiro, Matsuoka, Kaoru, Yasui, Takeshi, Yasutomo, Koji, Nomaguchi, Masako

“…Inactivation technology for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is certainly a critical measure to mitigate the spread of coronavirus…”
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Regulation of CD8 + T Cells and Antitumor Immunity by Notch Signaling by Tsukumo, Shin-Ichi, Yasutomo, Koji

“…Cancer immunosurveillance is critical for the elimination of neoplastic cells. In addition, recent advances in immunological checkpoint blockade drugs have…”
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Ultrasensitive detection of SARS-CoV-2 nucleocapsid protein using large gold nanoparticle-enhanced surface plasmon resonance by Yano, Taka-aki, Kajisa, Taira, Ono, Masayuki, Miyasaka, Yoshiya, Hasegawa, Yuichi, Saito, Atsushi, Otsuka, Kunihiro, Sakane, Ayuko, Sasaki, Takuya, Yasutomo, Koji, Hamajima, Rina, Kanai, Yuta, Kobayashi, Takeshi, Matsuura, Yoshiharu, Itonaga, Makoto, Yasui, Takeshi

“…The COVID-19 pandemic has created urgent demand for rapid detection of the SARS-CoV-2 coronavirus. Herein, we report highly sensitive detection of SARS-CoV-2…”
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A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans by Kitamura, Akiko, Maekawa, Yoichi, Uehara, Hisanori, Izumi, Keisuke, Kawachi, Izumi, Nishizawa, Masatoyo, Toyoshima, Yasuko, Takahashi, Hitoshi, Standley, Daron M, Tanaka, Keiji, Hamazaki, Jun, Murata, Shigeo, Obara, Koji, Toyoshima, Itaru, Yasutomo, Koji

“…Proteasomes are multisubunit proteases that play a critical role in maintaining cellular function through the selective degradation of ubiquitinated proteins…”
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Necroptosis protects against exacerbation of acute pancreatitis by Boonchan, Michittra, Arimochi, Hideki, Otsuka, Kunihiro, Kobayashi, Tomoko, Uehara, Hisanori, Jaroonwitchawan, Thiranut, Sasaki, Yuki, Tsukumo, Shin-ichi, Yasutomo, Koji

“…The sensing of various extrinsic stimuli triggers the receptor-interacting protein kinase-3 (RIPK3)-mediated signaling pathway, which leads to mixed-lineage…”
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Regulation of monocyte cell fate by blood vessels mediated by Notch signalling by Gamrekelashvili, Jaba, Giagnorio, Roberto, Jussofie, Jasmin, Soehnlein, Oliver, Duchene, Johan, Briseño, Carlos G., Ramasamy, Saravana K., Krishnasamy, Kashyap, Limbourg, Anne, Häger, Christine, Kapanadze, Tamar, Ishifune, Chieko, Hinkel, Rabea, Radtke, Freddy, Strobl, Lothar J., Zimber-Strobl, Ursula, Napp, L. Christian, Bauersachs, Johann, Haller, Hermann, Yasutomo, Koji, Kupatt, Christian, Murphy, Kenneth M., Adams, Ralf H., Weber, Christian, Limbourg, Florian P.

“…A population of monocytes, known as Ly6C lo monocytes, patrol blood vessels by crawling along the vascular endothelium. Here we show that endothelial cells…”
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Publisher Correction: Quantitative evaluation of SARS-CoV-2 inactivation using a deep ultraviolet light-emitting diode by Minamikawa, Takeo, Koma, Takaaki, Suzuki, Akihiro, Mizuno, Takahiko, Nagamatsu, Kentaro, Arimochi, Hideki, Tsuchiya, Koichiro, Matsuoka, Kaoru, Yasui, Takeshi, Yasutomo, Koji, Nomaguchi, Masako

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Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells by Ikeda, Kayo, Kinoshita, Makoto, Kayama, Hisako, Nagamori, Shushi, Kongpracha, Pornparn, Umemoto, Eiji, Okumura, Ryu, Kurakawa, Takashi, Murakami, Mari, Mikami, Norihisa, Shintani, Yasunori, Ueno, Satoko, Andou, Ayatoshi, Ito, Morihiro, Tsumura, Hideki, Yasutomo, Koji, Ozono, Keiichi, Takashima, Seiji, Sakaguchi, Shimon, Kanai, Yoshikatsu, Takeda, Kiyoshi

“…Foxp3+ regulatory T (Treg) cells, which suppress immune responses, are highly proliferative in vivo. However, it remains unclear how the active replication of…”
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Notch signaling drives IL-22 secretion in CD4⁺ T cells by stimulating the aryl hydrocarbon receptor by Alam, Muhammad Shamsul, Maekawa, Yoichi, Kitamura, Akiko, Tanigaki, Kenji, Yoshimoto, Takayuki, Kishihara, Kenji, Yasutomo, Koji

“…CD4⁺ helper T (Th) cells differentiate toward distinct effector cell lineages characterized by their distinct cytokine expression patterns and functions…”
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Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation by Sasaki, Yuki, Otsuka, Kunihiro, Arimochi, Hideki, Tsukumo, Shin-Ichi, Yasutomo, Koji

“…The NLRC4 inflammasome assembles in response to detection of bacterial invasion, and NLRC4 activation leads to the production of IL-1β and IL-18 together with…”
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Inactivation of SARS-CoV-2 by deep ultraviolet light emitting diode: A review by Minamikawa, Takeo, Koma, Takaaki, Suzuki, Akihiro, Nagamatsu, Kentaro, Yasui, Takeshi, Yasutomo, Koji, Nomaguchi, Masako

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally to cause severe damage to public health and economics…”
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Stimulation of the farnesoid X receptor promotes M2 macrophage polarization by Jaroonwitchawan, Thiranut, Arimochi, Hideki, Sasaki, Yuki, Ishifune, Chieko, Kondo, Hiroyuki, Otsuka, Kunihiro, Tsukumo, Shin-Ichi, Yasutomo, Koji

“…FXR is a key molecule that modulates anti-inflammatory activity in the intestinal-liver axis. Although FXR has pleiotropic functions including regulation of…”
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Preventive effect of fermented brown rice and rice bran on spontaneous type 1 diabetes in NOD female mice by Kataoka, Keiko, Nemoto, Hideyuki, Sakurai, Akiko, Yasutomo, Koji, Shikanai, Masataka

“…[Display omitted] •Brown rice and rice bran fermented with A. oryzae (FBRA) is a processed food.•Dietary administration of 0.5% FBRA delayed the spontaneous…”
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Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates by Suzuki, Yuta, Miyazaki, Takayuki, Muto, Hiroki, Kubara, Kenji, Mukai, Yohei, Watari, Ryuji, Sato, Shinya, Kondo, Keita, Tsukumo, Shin-ichi, Yasutomo, Koji, Ito, Masashi, Tsukahara, Kappei

“…mRNA and lipid nanoparticles have emerged as powerful systems for the preparation of vaccines against severe acute respiratory syndrome coronavirus-2…”
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Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production by Yoshida, Shinya, Yasutomo, Koji, Watanabe, Toshiyuki

“…Atopic dermatitis (AD) is caused by both dysregulated immune responses and an impaired skin barrier. Although leukotriene B4 (LTB4) is involved in tissue…”
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Rapid, high-sensitivity detection of biomolecules using dual-comb biosensing by Miyamura, Shogo, Oe, Ryo, Nakahara, Takuya, Koresawa, Hidenori, Okada, Shota, Taue, Shuji, Tokizane, Yu, Minamikawa, Takeo, Yano, Taka-Aki, Otsuka, Kunihiro, Sakane, Ayuko, Sasaki, Takuya, Yasutomo, Koji, Kajisa, Taira, Yasui, Takeshi

“…Rapid, sensitive detection of biomolecules is important for biosensing of infectious pathogens as well as biomarkers and pollutants. For example, biosensing of…”
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Markers of Memory CD8 T Cells Depicting the Effect of the BNT162b2 mRNA COVID-19 Vaccine in Japan by Kondo, Hiroyuki, Kageyama, Takahiro, Tanaka, Shigeru, Otsuka, Kunihiro, Tsukumo, Shin-Ichi, Mashimo, Yoichi, Onouchi, Yoshihiro, Nakajima, Hiroshi, Yasutomo, Koji

“…BNT162b2, a nucleoside-modified mRNA vaccine for SARS-CoV-2 spike glycoprotein (S), provides approximately 95% efficacy for preventing COVID-19. However, it…”
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