Search Results - "YARIM, Mine"

Cancer cell cytotoxicities of 1-(4-substitutedbenzoyl)-4-(4-chlorobenzhydryl)piperazine derivatives by Yarim, Mine, Koksal, Meric, Durmaz, Irem, Atalay, Rengul

“…A series of novel 1-(4-substitutedbenzoyl)-4-(4-chlorobenzhydryl)piperazine derivatives 5a-g was designed by a nucleophilic substitution reaction of…”
Get full text

Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives by Gurdal, Enise Ece, Buclulgan, Ebru, Durmaz, Irem, Cetin-Atalay, Rengul, Yarim, Mine

“…Synthesis, characterization and cytotoxic activities of ten benzothiazole-piperazine derivatives were reported. In vitro cytotoxic activities of compounds were…”
Get more information

Synthesis of Novel Benzothiazole-Piperazine Derivatives and Their Biological Evaluation as Acetylcholinesterase Inhibitors and Cytotoxic Agents by Gurdal, Enise Ece, Turgutalp, Bengisu, Gulcan, Hayrettin Ozan, Ercetin, Tugba, Sahin, Mustafa Fethi, Durmaz, Irem, Atalay, Rengul Cetin, Nguyen, Quoc Dat, Sippl, Wolfgang, Yarim, Mine

“…A new series of benzothiazole-piperazine derivatives was synthesized and a complete chemical characterization of the novel compounds was provided. In vitro…”
Get more information

Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents by AKKOÇ, MERİÇ KÖKSAL, YÜKSEL, MİNE YARIM, DURMAZ, İREM, ATALAY, RENGÜL ÇETİN

Get full text

Lead Optimization and Structure–Activity Relationship Studies on Myeloid Ecotropic Viral Integration Site 1 Inhibitor by Turgutalp, Bengisu, Uslu, Merve, Helvacioglu, Sinem, Charehsaz, Mohammad, Gurdal, Enise Ece, Sippl, Wolfgang, Kocabas, Fatih, Yarim, Mine

“…The pivotal role of the myeloid ecotropic viral integration site 1 (MEIS1) transcriptional factor was reported in cardiac regeneration and hematopoietic…”
Get full text

Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease by Turgutalp, Bengisu, Bhattarai, Prabesh, Ercetin, Tugba, Luise, Chiara, Reis, Rengin, Gurdal, Enise Ece, Isaak, Andreas, Biriken, Derya, Dinter, Elisabeth, Sipahi, Hande, Schepmann, Dirk, Junker, Anna, Wünsch, Bernhard, Sippl, Wolfgang, Gulcan, Hayrettin Ozan, Kizil, Caghan, Yarim, Mine

“…Drug development efforts that focused on single targets failed to provide effective treatment for Alzheimer’s disease (AD). Therefore, we designed…”
Get full text

Synthesis, Characterization, Molecular Docking, and Biological Activities of Some Natural and Synthetic Urolithin Analogs by Noshadi, Bahareh, Ercetin, Tugba, Luise, Chiara, Yuksel, Mine Yarim, Sippl, Wolfgang, Sahin, Mustafa Fethi, Gazi, Mustafa, Gulcan, Hayrettin Ozan

“…Urolithins (that is, hydroxy substituted benzo[c]chromen‐6‐one derivatives) are formed within the gastrointestinal tract following to the exposure to various…”
Get full text

Correction to “Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease” by Turgutalp, Bengisu, Bhattarai, Prabesh, Ercetin, Tugba, Luise, Chiara, Reis, Rengin, Gurdal, Enise Ece, Isaak, Andreas, Biriken, Derya, Dinter, Elisabeth, Sipahi, Hande, Schepmann, Dirk, Junker, Anna, Wünsch, Bernhard, Sippl, Wolfgang, Gulcan, Hayrettin Ozan, Kizil, Caghan, Yarim, Mine

Get full text

Comparison of separation performance of polysaccaride-based chiral stationary phases in enantioseparation of 1 by Gurdal, Enise Ece, Yarim, Mine

“…Analytical high-performance liquid chromatographic enantioseparation of 1-(4-chlorobenzhydryl)piperazine benzamide derivatives was accomplished on different…”
Get full text

Cytotoxic activities of some benzothiazole-piperazine derivatives by Gurdal, Enise Ece, Durmaz, Irem, Cetin-Atalay, Rengul, Yarim, Mine

“…Synthesis, characterization and cytotoxic activities of ten benzothiazole-piperazine derivatives were reported. In vitro cytotoxic activities of compounds were…”
Get more information

Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease by Shukur, Karar T., Ercetin, Tugba, Luise, Chiara, Sippl, Wolfgang, Sirkecioglu, Okan, Ulgen, Mert, Coskun, Goknil P., Yarim, Mine, Gazi, Mustafa, Gulcan, Hayrettin O.

“…A series of urolithin amide (i.e., URO‐4–URO‐10 and THU‐4–THU‐10) derivatives was designed and synthesized, and their chemical structures were confirmed with…”
Get full text

Crystal Structure of 4-(4-Bromophenyl)-1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione by CANDAN, M. Murat, KENDI, Engin, YARIM, Mine, SARAÇ, Selma, ERTAN, Mevlüt

Get full text

Synthesis and cytotoxicity studies of novel benzhydrylpiperazine carboxamide and thioamide derivatives by Gurdal, Enise Ece, Durmaz, Irem, Cetin-Atalay, Rengul, Yarim, Mine

“…Synthesis and cytotoxic activities of 32 benzhydrylpiperazine derivatives with carboxamide and thioamide moieties were reported. In vitro cytotoxic activities…”
Get more information

Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands by Yarim, Mine, Koksal, Meric, Schepmann, Dirk, Wünsch, Bernard

“…To investigate the molecular features involved in sigma (σ) receptors binding, a series of compounds based on indole scaffolds were synthesized and their…”
Get full text

Comparison of separation performance of polysaccaride-based chiral stationary phases in enantioseparation of 1-(4-chlorobenzhydryl)piperazine benzamide derivatives by HPLC by Gurdal, Enise Ece, Yarim, Mine

“…Analytical high-performance liquid chromatographic enantioseparation of 1-(4-chlorobenzhydryl) piperazine benzamide derivatives was accomplished on different…”
Get full text

Crystal Structure of 1,7,7-Trimethyl-4-(4-methylphenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione by CANDAN, M. Murat, KENDI, Engin, Yarim, Mine, SARAÇ, Selma, ERTAN, Mevlüt

Get full text

Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates by Yarim, Mine, Moro, Stefano, Huber, Robert, Meier, Peter J., Kaseda, Chosei, Kashima, Toru, Hagenbuch, Bruno, Folkers, Gerd

“…We used three-dimensional quantitative structure–activity relationship (3D-QSAR) techniques to obtain topological information on the substrate binding site of…”
Get full text

Primum non nocere: In silico prediction of adverse drug reactions of antidepressant drugs by Güneş, Serdar Sinan, Yeşil, Çağrı, Gurdal, Enise Ece, Korkmaz, Emin Erkan, Yarım, Mine, Aydın, Ahmet, Sipahi, Hande

“…[Display omitted] •Best performing attribute group was Chem + Biol.•Multilayer perceptron algorithm surpassed the others.•ADRs belonging to 5 SOCs were…”
Get full text

Studies on Synthesis, Chromatographic Resolution, and Antiinflammatory Activities of Some 2-Thioxo-1,2,3,4-tetrahydropyrimidines and Their Condensed Derivatives by Tozkoparan, Birsen, Yarim, Mine, Saraç, Selma, Ertan, Mevlüt, Kelicen, Pelin, Altinok, Gülçin, Demirdamar, Rümeysa

“…In this study, the synthesis of some new 2‐thioxo‐1,2,3,4‐tetrahydropyrimidines and their condensed derivatives, thiazolo[3,2‐α] pyrimidines, are described…”
Get full text

Crystal structure of 1,7,7-trimethyl-4-(4-methylphenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dion e by CANDAN, M. Murat, KENDI, Engin, YARIM, Mine, SARAC, Selma, ERTAN, Mevlüt

Get full text