Search Results - "YAPICI, Engin"

Lanthanide-Based Imaging of Protein–Protein Interactions in Live Cells by Rajendran, Megha, Yapici, Engin, Miller, Lawrence W

“…In order to deduce the molecular mechanisms of biological function, it is necessary to monitor changes in the subcellular location, activation, and interaction…”
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Evaluation and discrimination of simvastatin-induced structural alterations in proteins of different rat tissues by FTIR spectroscopy and neural network analysis by Garip, Sebnem, Yapici, Engin, Ozek, Nihal Simsek, Severcan, Mete, Severcan, Feride

“…Statins are commonly used to control hypercholesterolemia and to prevent cardiovascular diseases. Among the statins, Simvastatin is one of the most frequently…”
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Automated Design of Macrocycles for Therapeutic Applications: From Small Molecules to Peptides and Proteins by Sindhikara, Dan, Wagner, Michael, Gkeka, Paraskevi, Güssregen, Stefan, Tiwari, Garima, Hessler, Gerhard, Yapici, Engin, Li, Ziyu, Evers, Andreas

“…Macrocycles and cyclic peptides are increasingly attractive therapeutic modalities as they often have improved affinity, are able to bind to extended protein…”
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Abstract 1338: Discovery of novel, potent USP7 inhibitors that upregulate p53 leading to anti-proliferative effects in cancer cells by Futran, Alan, Lu, Tao, Amberg-Johnson, Katherine, Yang, Xiaoxiao, He, Saidi, Bell, Jeffrey, Boyce, Sarah, Dahlgren, Markus, Dingley, Karen, Fang, Liping, Koldsoe, Heidi, Konst, Zef, Lin, Fang-Yu, Pelleltier, Robert, Qian, Heng, Svensson, Mats, Trzoss, Michael, Xu, Jie, Xu, Shuping, Xu, Zhaowu, Yapici, Engin, Zhang, Yan, Xing, Li, Suzuki, Takao, Huang, Xianhai, Xu, Jiayi, Wright, Hamish, Jensen, Kristian, Tang, Wayne, Guo, Tao, Akinsanya, Karen, Madge, David

“…Abstract Introduction: Ubiquitin-specific protease 7 (USP7) is a deubiquitinase that regulates several proteins involved in cell cycle, DNA repair, genomic…”
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Cover Picture: An Adaptable Luminescence Resonance Energy Transfer Assay for Measuring and Screening Protein-Protein Interactions and their Inhibition. (ChemBioChem 4/2012) by Yapici, Engin, Reddy, D. Rajasekhar, Miller, Lawrence W.

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An Adaptable Luminescence Resonance Energy Transfer Assay for Measuring and Screening Protein-Protein Interactions and their Inhibition by Yapici, Engin, Reddy, D. Rajasekhar, Miller, Lawrence W.

“…Protein–protein interactions (PPIs) are central to biological processes and represent an important class of therapeutic targets. Here we show that the…”
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Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions by Yapici, Engin

“…High throughput screening (HTS) assays are a key component of the drug discovery processes. They are designed to identify biologically active molecules that…”
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Local or Spinal Anesthesia in Subinguinal Varicocelectomy: A Prospective Randomized Trial by Kadihasanoglu, Mustafa, Karaguzel, Ersagun, Kacar, Cem Kivilcim, Arıkan, Mehmet Salih, Yapıcı, Mustafa Engin, Türkmen, Nihat

“…Objective To determine whether local anesthesia (LA) is an acceptable alternative to spinal anesthesia (SA) for varicocelectomy. Methods A total of 60 men with…”
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Sezaryenlerde spinal veya kombine spinal epidural anestezi öncesi uygulanan hipertonik sodyum klorür, hidroksietil nişasta ve ringer laktat solüsyonlarının hipotansiyon üzerine etkileri by GÜLHAŞ, Nurçin, ERDİL, Feray, KÖROĞLU, Ahmet, YAPICI, Engin, BUT, A. Kadir, ERSOY, M. Özcan

“…Amaç: Çalışmamızda spinal veya kombine spinal epidural anestezi (KSEA) sırasında gelişebilecek maternal hipotansiyonun önlenmesinde farklı hidrasyon…”
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Sezaryenlerde bupivakain ve ropivakainin hemodinami üzerine etkileri by GÜLHAŞ, Nurçin, BEGEÇ, Zekine, BUT, Abdulkadir, YAPICI, Engin, ÖZTÜRK, Erdoğan, DOĞAN, Zafer, ERSOY, Mehmet Özcan

“…Giriş: Spinal anestezide lokal anestezikler, yaptıkları duyusal-motor blok nedeniyle hasta ve cerrah için konforlu bir anestezi sağlarken gelişen sempatik blok…”
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