Search Results - "YAO, Kozo"

Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells by Yuan, Bo, Kikuchi, Hidetomo, Li, Jingmei, Kawabata, Atsushi, Yao, Kozo, Takagi, Norio, Okazaki, Mari

“…To explore the molecular mechanisms of action underlying the antileukemia activities of darinaparsin, an organic arsenical approved for the treatment of…”
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Pharmacological, Pharmacokinetic, and Clinical Properties of Benidipine Hydrochloride, a Novel, Long-Acting Calcium Channel Blocker by Yao, Kozo, Nagashima, Ken, Miki, Hiroyuki

“…Benidipine is a dihydropyridine-derived calcium channel blocker developed in Japan, with several unique mechanisms of action, that is, triple calcium channels…”
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Effects of Benidipine, a Long-Lasting Dihydropyridine-Ca2+ Channel Blocker, on Cerebral Blood Flow Autoregulation in Spontaneously Hypertensive Rats by Ikeda, Jun-ichi, Yao, Kozo, Matsubara, Masahiro

“…Chronic hypertension shifts cerebral blood flow (CBF) autoregulation towards higher blood pressure. We examined whether or not benidipine, a long-lasting…”
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The dihydropyridine calcium channel blocker benidipine prevents lysophosphatidylcholine-induced endothelial dysfunction in rat aorta by Takayama, Makoto, Yao, Kozo, Wada, Michihito

“…Lysophosphatidylcholine (LPC), an atherogenic component of oxidized low-density lipoprotein, has been shown to induce the attenuation of endothelium-dependent…”
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Combined Effects of Benidipine and Diltiazem in a Rat Model of Experimental Angina by Yao, Kozo, Shirakura, Shiro

“…We examined the combined effects of the calcium channel blockers 1,4-dihydropyridine (benidipine) and benzothiazepine (diltiazem) on vasopressin-induced…”
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Comparison of the antiatherosclerotic effects of dihydropyridine calcium channel blocker and HMG-CoA reductase inhibitor on hypercholesterolemic rabbits by Takayama, Makoto, Matsubara, Masahiro, Arakawa, Emi, Takada, Chie, Ina, Yasuhiro, Hasegawa, Kazuhide, Yao, Kozo

“…Abstract The antiatherosclerotic effects of the dihydropyridine-type calcium channel blocker, benidipine hydrochloride (benidipine), and…”
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Combined Effects of Benidipine and Diltiazem on Cardiohemodynamics in Anesthetized Dogs by Yao, Kozo, Maeda, Hiroshi, Ina, Yasuhiro, Sato, Miwa, Fujita, Kazuhiro, Kuwabara, Takashi, Kobayashi, Hiroyuki, Shirakura, Shiro

“…We examined the combined effects of the calcium channel blockers 1,4-dihydropyridine (benidipine) and benzothiazepine (diltiazem) on cardiohemodynamics in…”
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Effects of Benidipine and Candesartan on Kidney and Vascular Function in Hypertensive Dahl Rats by YAO, Kozo, SATO, Hitoshi, SONODA, Rie, INA, Yasuhiro, SUZUKI, Kazuo, OHNO, Tetsuji

“…We examined the effect of the dihydropyridine calcium channel blocker (CCB) benidipine, the angiotensin II type 1 receptor blocker (ARB) candesartan, and the…”
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Antioxidant Effects of Calcium Antagonists in Rat Brain Homogenates by YAO, Kozo, INA, Yazuhiro, NAGASHIMA, Ken, OHMORI, Kenji, OHNO, Tetsuji

“…We studied the antioxidant activities of calcium antagonists against autoxidation in rat brain homogenates.The homogenates were incubated for 30 min at 37°C…”
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Renoprotective Effects of Benidipine in Combination with Angiotensin II Type 1 Receptor Blocker in Hypertensive Dahl Rats by YAO, Kozo, SATO, Hitoshi, INA, Yasuhiro, SUZUKI, Kazuo, OHNO, Tetsuji, SHIRAKURA, Shiro

“…We examined the effects of the angiotensin II type 1 receptor blocker candesartan, the calcium channel blockers benidipine and amlodipine, hydralazine, and the…”
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Effects of Benidipine in a Rat Model of Experimental Angina by IKEDA, Jun-ichi, MATSUBARA, Masahiro, YAO, Kozo

“…To compare the antianginal effects of 1,4-dihydropyridine-type calcium-channel blockers, we evaluated the effects of benidipine, amlodipine, nifedipine, and…”
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Protective effects of benidipine on hydrogen peroxide-induced injury in rat isolated hearts by Yao, Kozo, Ina, Yasuhiro, Sonoda, Rie, Nagashima, Ken, Ohmori, Kenji, Ohno, Tetsuji

“…ABSTRACT We investigated the effects of benidipine (hydrochloride), a calcium antagonist, on hydrogen peroxide (H2O2)‐induced injury in Langendorff‐perfused…”
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Paclitaxel-induced peripheral neuropathy in male rats attenuated by calmangafodipir, a superoxide dismutase mimetic by Kawashiri, Takehiro, Mori, Kohei, Ishida, Haruna, Ueda, Mami, Yao, Kozo, Nagahama, Fumiko, Mine, Keisuke, Mori, Yusuke, Koura, Yusuke, Fujita, Shunsuke, Shimazoe, Takao, Kobayashi, Daisuke

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Benidipine, a Dihydropyridine-Ca2+ Channel Blocker, Increases the Endothelial Differentiation of Endothelial Progenitor Cells In Vitro by ANDO, Hiroshi, NAKANISHI, Kosuke, SHIBATA, Mami, HASEGAWA, Kazuhide, YAO, Kozo, MIYAJI, Hiromasa

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Studies of Cardiotonic Agents. 8. Synthesis and Biological Activities of Optically Active 6-(4-(Benzylamino)-7-quinazolinyl)-4,5-dihydro-5-methyl- 3(2H)-pyridazinone (KF15232) by Nomoto, Yuji, Takai, Haruki, Ohno, Tetsuji, Nagashima, Ken, Yao, Kozo, Yamada, Koji, Kubo, Kazuhiro, Ichimura, Michio, Mihara, Akira, Kase, Hiroshi

“…We previously reported that (±)-6-(4-(benzylamino)-7-quinazolinyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone ((±)-1, KF15232) showed potent cardiotonic activity…”
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Benidipine Inhibits Apoptosis During Ischaemic Acute Renal Failure in Rats by YAO, KOZO, SATO, HITOSHI, INA, YASUHIRO, NAGASHIMA, KEN, NISHIKAWA, SATOSHI, OHMORI, KENJI, OHNO, TETSUJI

“…We have investigated the effects of benidipine (hydrochloride), a calcium antagonist, against ischaemic acute renal failure in rats. Using histological…”
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Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R by Akizuki, Osamu, Inayoshi, Atsushi, Kitayama, Tetsuya, Yao, Kozo, Shirakura, Shiro, Sasaki, Katsutoshi, Kusaka, Hideaki, Matsubara, Masahiro

“…Benidipine, a long-lasting dihydropyridine calcium channel blocker, is used for treatment of hypertension and angina. Benidipine exerts pleiotropic…”
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Protective Effects of Benidipine against Myocardial Damage Following Ischemia and Reperfusion in the Isolated Perfused Rat Heart by YAO, Kozo, KARASAWA, Akira

“…We investigated the possible protective effects of benidipine (Coniel[○!R]), a calcium antagonist, on mechanical dysfunction, metabolic damage and changes in…”
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Benidipine, a dihydropyridine-calcium channel blocker, inhibits lysophosphatidylcholine-induced endothelial injury via stimulation of nitric oxide release by Matsubara, Masahiro, Yao, Kozo, Hasegawa, Kazuhide

“…Benidipine hydrochloride (benidipine), which is a long-lasting dihydropyridine calcium channel blocker, exerts antihypertensive action via inhibition of Ca 2+…”
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近位尿細管へのgentamicin蓄積に対する選択的アデノシンA1受容体拮抗薬KW-3902の作用 by 矢尾, 幸三

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