Search Results - "YANLING WU"

G-quadruplex stabilization via small-molecules as a potential anti-cancer strategy by Awadasseid, Annoor, Ma, Xudong, Wu, Yanling, Zhang, Wen

“…G-quadruplexes (G4) are secondary four-stranded DNA helical structures consisting of guanine-rich nucleic acids, which can be formed in the promoter regions of…”
Get full text

Seasonal predictability of the tropical Indian Ocean SST in the North American multimodel ensemble by Wu, Yanling, Tang, Youmin

“…In this study, we investigate the predictability of the tropical Indian Ocean (TIO) sea surface temperature anomalies (SSTA) using the recently released North…”
Get full text

Effective drugs used to combat SARS-CoV-2 infection and the current status of vaccines by Awadasseid, Annoor, Wu, Yanling, Tanaka, Yoshimasa, Zhang, Wen

“…[Display omitted] •Drug repurposing, depicting patented medicines as an effective technique to develop drugs.•Drug repurposing, compared to de novo drug…”
Get full text

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein by Xia, Shuai, Zhu, Yun, Liu, Meiqin, Lan, Qiaoshuai, Xu, Wei, Wu, Yanling, Ying, Tianlei, Liu, Shuwen, Shi, Zhengli, Jiang, Shibo, Lu, Lu

Get full text

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody by Tian, Xiaolong, Li, Cheng, Huang, Ailing, Xia, Shuai, Lu, Sicong, Shi, Zhengli, Lu, Lu, Jiang, Shibo, Yang, Zhenlin, Wu, Yanling, Ying, Tianlei

“…The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a…”
Get full text

Identification of Human Single-Domain Antibodies against SARS-CoV-2 by Wu, Yanling, Li, Cheng, Xia, Shuai, Tian, Xiaolong, Kong, Yu, Wang, Zhi, Gu, Chenjian, Zhang, Rong, Tu, Chao, Xie, Youhua, Yang, Zhenlin, Lu, Lu, Jiang, Shibo, Ying, Tianlei

“…The worldwide spread of COVID-19 highlights the need for an efficient approach to rapidly develop therapeutics and prophylactics against SARS-CoV-2. The…”
Get full text

A New Type of the Indian Ocean Dipole since the Mid-1970s by Du, Yan, Cai, Wenju, Wu, Yanling

“…The tropical Indian Ocean dipole/zonal mode (IOD) is phase locked with the austral winter and spring seasons. This study describes three types of the IOD in…”
Get full text

Probiotics improve polystyrene microplastics-induced male reproductive toxicity in mice by alleviating inflammatory response by Zhang, Yecui, Hou, Baolian, Liu, Tao, Wu, Yanling, Wang, Zhiping

“…As a new type of environmental pollutant, microplastics have been garnered increasing attention, especially in regard to their effects on the reproductive…”
Get full text

Single-Domain Antibodies As Therapeutics against Human Viral Diseases by Wu, Yanling, Jiang, Shibo, Ying, Tianlei

“…In full-size formats, monoclonal antibodies have been highly successful as therapeutics against cancer and immune diseases. However, their large size leads to…”
Get full text

Research and Application of Hydraulic Punching Pressure Relief Antireflection Mechanism in Deep “Three-Soft” Outburst Coal Seam by Gu, Beifang, Wu, Yanling

“…To solve the problems of gas predrainage in deep seams with “three softs” and low-air permeability, hydraulic punching pressure relief antireflection…”
Get full text

Potential protective role of the anti-PD-1 blockade against SARS-CoV-2 infection by Awadasseid, Annoor, Yin, Qiang, Wu, Yanling, Zhang, Wen

“…The outbreak of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, in December 2019, and its global dissemination became the…”
Get full text

A meta-analysis for the diagnostic accuracy of SelectMDx in prostate cancer by Wu, Hanting, Wu, Yanling, He, Peijie, Liang, Juan, Xu, Xiujuan, Ji, Conghua

“…To overview the diagnostic accuracy of SelectMDx for the detection of clinically significant prostate cancer and to review sources of methodologic variability…”
Get full text

Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection by Wan, Jinkai, Xing, Shenghui, Ding, Longfei, Wang, Yongheng, Gu, Chenjian, Wu, Yanling, Rong, Bowen, Li, Cheng, Wang, Siqing, Chen, Kun, He, Chenxi, Zhu, Dandan, Yuan, Songhua, Qiu, Chengli, Zhao, Chen, Nie, Lei, Gao, Zhangzhao, Jiao, Jingyu, Zhang, Xiaoyan, Wang, Xiangxi, Ying, Tianlei, Wang, Haibin, Xie, Youhua, Lu, Yanan, Xu, Jianqing, Lan, Fei

“…Coronavirus disease 2019 (COVID-19) has become a worldwide threat to humans, and neutralizing antibodies have therapeutic potential. We have purified more than…”
Get full text

Corrigendum to “G-quadruplex stabilization via small-molecules as a potential anti-cancer strategy” [Biomed. Pharmacother. 139 (2021) 111550] by Awadasseid, Annoor, Ma, Xudong, Wu, Yanling, Zhang, Wen

Get full text

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion by Vergari, Elisa, Knudsen, Jakob G., Ramracheya, Reshma, Salehi, Albert, Zhang, Quan, Adam, Julie, Asterholm, Ingrid Wernstedt, Benrick, Anna, Briant, Linford J. B., Chibalina, Margarita V., Gribble, Fiona M., Hamilton, Alexander, Hastoy, Benoit, Reimann, Frank, Rorsman, Nils J. G., Spiliotis, Ioannis I., Tarasov, Andrei, Wu, Yanling, Ashcroft, Frances M., Rorsman, Patrik

“…Hypoglycaemia (low plasma glucose) is a serious and potentially fatal complication of insulin-treated diabetes. In healthy individuals, hypoglycaemia triggers…”
Get full text

Single-Domain Antibodies as Therapeutics for Respiratory RNA Virus Infections by Huang, Keke, Ying, Tianlei, Wu, Yanling

“…Over the years, infectious diseases with high morbidity and mortality disrupted human healthcare systems and devastated economies globally. Respiratory…”
Get full text

Author Correction: Pretrainable geometric graph neural network for antibody affinity maturation by Cai, Huiyu, Zhang, Zuobai, Wang, Mingkai, Zhong, Bozitao, Li, Quanxiao, Zhong, Yuxuan, Wu, Yanling, Ying, Tianlei, Tang, Jian

Get full text

A Transfer-Learning-Based Deep Convolutional Neural Network for Predicting Leukemia-Related Phosphorylation Sites from Protein Primary Sequences by He, Jian, Wu, Yanling, Pu, Xuemei, Li, Menglong, Guo, Yanzhi

“…As one of the most important post-translational modifications (PTMs), phosphorylation refers to the binding of a phosphate group with amino acid residues like…”
Get full text

Pretrainable geometric graph neural network for antibody affinity maturation by Cai, Huiyu, Zhang, Zuobai, Wang, Mingkai, Zhong, Bozitao, Li, Quanxiao, Zhong, Yuxuan, Wu, Yanling, Ying, Tianlei, Tang, Jian

“…Increasing the binding affinity of an antibody to its target antigen is a crucial task in antibody therapeutics development. This paper presents a pretrainable…”
Get full text

Adiponectin protects against development of metabolic disturbances in a PCOS mouse model by Benrick, Anna, Chanclón, Belén, Micallef, Peter, Wu, Yanling, Hadi, Laila, Shelton, John M., Stener-Victorin, Elisabet, Asterholm, Ingrid Wernstedt

“…Adiponectin, together with adipocyte size, is the strongest factor associated with insulin resistance in women with polycystic ovary syndrome (PCOS). This…”
Get full text