Search Results - "YANG, Yimu"

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis by Schmidt, Eric P, Yang, Yimu, Janssen, William J, Gandjeva, Aneta, Perez, Mario J, Barthel, Lea, Zemans, Rachel L, Bowman, Joel C, Koyanagi, Dan E, Yunt, Zulma X, Smith, Lynelle P, Cheng, Sara S, Overdier, Katherine H, Thompson, Kathy R, Geraci, Mark W, Douglas, Ivor S, Pearse, David B, Tuder, Rubin M

“…The glycocalyx is a layer of proteoglycans and complex carbohydrates that lines the endothelial cell surface in blood vessels. Schmidt et al . show that in…”
Get full text

Heparan Sulfate in the Developing, Healthy, and Injured Lung by Haeger, Sarah M, Yang, Yimu, Schmidt, Eric P

“…Remarkable progress has been achieved in understanding the regulation of gene expression and protein translation, and how aberrancies in these template-driven…”
Get full text

Urinary Glycosaminoglycans Predict Outcomes in Septic Shock and Acute Respiratory Distress Syndrome by Schmidt, Eric P, Overdier, Katherine H, Sun, Xiaojun, Lin, Lei, Liu, Xinyue, Yang, Yimu, Ammons, Lee Anne, Hiller, Terra D, Suflita, Matt A, Yu, Yanlei, Chen, Yin, Zhang, Fuming, Cothren Burlew, Clay, Edelstein, Charles L, Douglas, Ivor S, Linhardt, Robert J

“…Degradation of the endothelial glycocalyx, a glycosaminoglycan (GAG)-rich layer lining the vascular lumen, is associated with the onset of kidney injury in…”
Get full text

Circulating heparan sulfate fragments mediate septic cognitive dysfunction by Hippensteel, Joseph A, Anderson, Brian J, Orfila, James E, McMurtry, Sarah A, Dietz, Robert M, Su, Guowei, Ford, Joshay A, Oshima, Kaori, Yang, Yimu, Zhang, Fuming, Han, Xiaorui, Yu, Yanlei, Liu, Jian, Linhardt, Robert J, Meyer, Nuala J, Herson, Paco S, Schmidt, Eric P

“…Septic patients frequently develop cognitive impairment that persists beyond hospital discharge. The impact of sepsis on electrophysiological and molecular…”
Get full text

The Circulating Glycosaminoglycan Signature of Respiratory Failure in Critically Ill Adults by Schmidt, Eric P., Li, Guoyun, Li, Lingyun, Fu, Li, Yang, Yimu, Overdier, Katherine H., Douglas, Ivor S., Linhardt, Robert J.

“…Systemic inflammatory illnesses (such as sepsis) are marked by degradation of the endothelial glycocalyx, a layer of glycosaminoglycans (including heparan…”
Get full text

Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE by Li, Miaomiao, Ong, Chih Yean, Langouët-Astrié, Christophe J, Tan, Lisi, Verma, Ashwni, Yang, Yimu, Zhang, Xiaoxiao, Shah, Dhaval K, Schmidt, Eric P, Xu, Ding

“…RAGE, a druggable inflammatory receptor, is known to function as an oligomer but the exact oligomerization mechanism remains poorly understood. Previously we…”
Get full text

Aquaporins in avian kidneys: function and perspectives by Nishimura, Hiroko, Yang, Yimu

“…For terrestrial vertebrates, water economy is a prerequisite for survival, and the kidney is their major osmoregulatory organ. Birds are the only vertebrates…”
Get more information

Fibroblast Growth Factor Signaling Mediates Pulmonary Endothelial Glycocalyx Reconstitution by Yang, Yimu, Haeger, Sarah M, Suflita, Matthew A, Zhang, Fuming, Dailey, Kyrie L, Colbert, James F, Ford, Joshay A, Picon, Mario A, Stearman, Robert S, Lin, Lei, Liu, Xinyue, Han, Xiaorui, Linhardt, Robert J, Schmidt, Eric P

“…The endothelial glycocalyx is a heparan sulfate (HS)-rich endovascular structure critical to endothelial function. Accordingly, endothelial glycocalyx…”
Get full text

Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-α antibodies by Bhargava, Rhea, Altmann, Christopher J, Andres-Hernando, Ana, Webb, Ryan G, Okamura, Kayo, Yang, Yimu, Falk, Sandor, Schmidt, Eric P, Faubel, Sarah

“…Acute kidney injury (AKI) and acute lung injury (ALI) are serious complications of sepsis. AKI is often viewed as a late complication of sepsis. Notably, the…”
Get full text

A model-specific role of microRNA-223 as a mediator of kidney injury during experimental sepsis by Colbert, James F, Ford, Joshay A, Haeger, Sarah M, Yang, Yimu, Dailey, Kyrie L, Allison, Kristen C, Neudecker, Viola, Evans, Christopher M, Richardson, Vanessa L, Brodsky, Kelley S, Faubel, Sarah, Eltzschig, Holger K, Schmidt, Eric P, Ginde, Adit A

“…Sepsis outcomes are heavily dependent on the development of septic organ injury, but no interventions exist to interrupt or reverse this process. microRNA-223…”
Get more information

Circulating Heparan Sulfate Fragments Attenuate Histone-Induced Lung Injury Independently of Histone Binding by Zhang, Yanlin, Haeger, Sarah M, Yang, Yimu, Dailey, Kyrie L, Ford, Joshay A, Schmidt, Eric P

“…ABSTRACTExtracellular histones are cationic damage-associated molecular pattern molecules capable of directly inducing cellular injury via charge-mediated…”
Get full text

In vivo measurement of the mouse pulmonary endothelial surface layer by Yang, Yimu, Yang, Gaoqing, Schmidt, Eric P

“…The endothelial glycocalyx is a layer of proteoglycans and associated glycosaminoglycans lining the vascular lumen. In vivo, the glycocalyx is highly hydrated,…”
Get full text

Two distinct aquaporin-4 cDNAs isolated from medullary cone of quail kidney by Yang, Yimu, Cui, Yujun, Fan, Zheng, Cook, George A., Nishimura, Hiroko

“…Water deprivation or arginine vasotocin upregulates aquaporin-2 (AQP2) expression in apical and subapical regions of medullary collecting duct (CD) cells of…”
Get full text

PAPR suppressing matrix transform and dual layered phase sequencing design for a chaos-based multi-carrier CDMA VLC system by Feng, Yan, Yang, Yimu, Li, Diyang, Zhang, Lin

“…In this paper, we propose a chaos-based visible light communication system, wherein multiple users can access the network via the multi-carrier code division…”
Get full text

Direct acoustic communication between underwater and airborne nodes by Yang, Shaojian, Yang, Yimu, Tu, Xingbin, Lu, Xuesong, Yan, Wei, Qu, Fengzhong

“…Direct acoustic communication between underwater and airborne nodes has always been considered unfeasible due to the energy loss caused by the strong surface…”
Get full text

Immunocytochemical analysis of sex differences in calcitonin gene-related peptide in the rat dorsal root ganglion, with special reference to estrogen and its receptor by Yang, Yimu, Ozawa, Hitoshi, Lu, Haiping, Yuri, Kazunari, Hayashi, Shinji, Nihonyanagi, Kenji, Kawata, Mitsuhiro

“…Previous studies have shown that the calcitonin gene-related peptide (CGRP) immunoreactivity in the central nervous system (CNS) of adult rats is sexually…”
Get full text

Engineered CRISPR RNA improves the RNA cleavage efficiency of hfCas13X by Liu, Zehui, Zhang, Wenxia, Wang, Haili, Shangguan, Pingping, Pan, Tong, Yang, Yimu, Zhang, Yi, Mao, Xi, Liu, Yingle, Zhang, Qi

“…As the most compact variant in the Cas13 family, CRISPR‐Cas13X holds considerable promise for gene therapy applications. The development of high‐fidelity…”
Get full text

Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions by Zhang, Xing, Han, Xiaorui, Xia, Ke, Xu, Yongmei, Yang, Yimu, Oshima, Kaori, Haeger, Sarah M., Perez, Mario J., McMurtry, Sarah A., Hippensteel, Joseph A., Ford, Joshay A., Herson, Paco S., Liu, Jian, Schmidt, Eric P., Linhardt, Robert J.

“…Sepsis induces heparanase-mediated degradation of the endothelial glycocalyx, a heparan sulfate-enriched endovascular layer critical to vascular homeostasis,…”
Get full text

Heparanase contributes to idiopathic pulmonary fibrosis via regulation of A20/TNFAIP3 expression by Yang, Yimu, Lara, Abigail, Rutebemberwa, Alleluiah, Schmidt, Eric

“…Abstract only We have previously demonstrated that heparanase, a mammalian endoglycosidase that cleaves the extracellular glycosaminoglycan heparan sulfate…”
Get full text

The endothelial glycocalyx: An important regulator of the pulmonary vascular barrier by Yang, Yimu, Schmidt, Eric P.

“…Once thought to be a structure of small size and uncertain significance, the endothelial glycocalyx is now known to be an important regulator of endothelial…”
Get full text