Search Results - "YANAI, Ayako"
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Constitutive NF-κB Activation in Colorectal Carcinoma Plays a Key Role in Angiogenesis, Promoting Tumor Growth
Published in Clinical cancer research (01-04-2009)“…Purpose: Nuclear factor κB (NF-κB) is an important transcription factor in various biological processes. Constitutive NF-κB activation has been noted in many…”
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A survey of antimicrobial resistance in Escherichia coli isolated from wild sika deer (Cervus nippon) in Japan
Published in Journal of Veterinary Medical Science (2021)“…We examined the antimicrobial susceptibility of 848 Escherichia coli isolates from 237 feces samples of wild sika deer (Cervus nippon) captured between 2016…”
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Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2008)“…Background & Aims: Acetaminophen (APAP) overdose is the most frequent cause of drug-induced liver failure. C-jun N-terminal kinase (JNK) is thought to play a…”
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Risk factors and early signs of pancreatic cancer in diabetes: screening strategy based on diabetes onset age
Published in Journal of gastroenterology (01-02-2013)“…Background Diabetes mellitus (DM) has long been recognized as a risk factor for pancreatic cancer (PaC) and recently has attracted attention as a manifestation…”
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Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer
Published in International journal of oncology (01-05-2018)“…Triple-negative breast cancer (TNBC), defined as breast cancer lacking estrogen- and progesterone-receptor expression and human epidermal growth factor…”
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C-Jun NH2-Terminal Kinase 1 Is a Critical Regulator for the Development of Gastric Cancer in Mice
Published in Cancer research (Chicago, Ill.) (01-07-2008)“…c-Jun NH(2)-terminal kinase (JNK) links several cellular processes, including proliferation and survival, and is believed to be involved in carcinogenesis…”
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Duplication of blaCTX-M-1 and a class 1 integron on the chromosome enhances antimicrobial resistance in Escherichia coli isolated from racehorses in Japan
Published in Journal of global antimicrobial resistance. (01-12-2021)“…•Two extended-spectrum β-lactamase-producing Escherichia coli strains were isolated from diseased horses in Japan.•An antimicrobial resistance (AMR) gene…”
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Essential roles of high-mobility group box 1 in the development of murine colitis and colitis-associated cancer
Published in Biochemical and biophysical research communications (24-08-2007)“…High-mobility group box 1 (HMGB1) is a nuclear factor released extracellularly as a proinflammatory cytokine. We measured the HMGB1 concentration in the sera…”
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Prognostic significance of geminin expression levels in Ki67-high subset of estrogen receptor-positive and HER2-negative breast cancers
Published in Breast cancer (Tokyo, Japan) (01-03-2016)“…Background Indication for chemotherapy in estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancers is…”
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Impact of biomarker changes during neoadjuvant chemotherapy for clinical response in patients with residual breast cancers
Published in International journal of clinical oncology (01-04-2016)“…Background Residual cancer burden or Ki67 expression levels in residual tumors reportedly provided significant prognostic information for a non-pathological…”
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The Effect of Helicobacter pylori Eradication on Reducing the Incidence of Gastric Cancer
Published in Journal of clinical gastroenterology (01-03-2008)“…Epidemiologically, the association between chronic Helicobacter pylori infection and development of gastric cancer is well established. Although the…”
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Different patterns of change in bone turnover markers during treatment with bone-modifying agents for breast cancer patients with bone metastases
Published in Breast cancer (Tokyo, Japan) (01-03-2017)“…Background Bone-modifying agents are effective for treatment of breast cancer patients with bone metastases. Since their action is mediated through suppression…”
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Effectiveness of IκB kinase inhibitors in murine colitis-associated tumorigenesis
Published in Journal of gastroenterology (01-09-2009)“…Purpose Nuclear factor κB (NF-κB) activation is involved in various inflammatory illnesses, for example inflammatory bowel disease, and is thought to be a key…”
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Sitafloxacin resistance in Helicobacter pylori isolates and sitafloxacin-based triple therapy as a third-line regimen in Japan
Published in International journal of antimicrobial agents (01-04-2012)“…Abstract The third-line treatment regimen for Helicobacter pylori after failure of clarithromycin- and metronidazole-based therapies is not yet established…”
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Gastric cancer diagnosed after Helicobacter pylori eradication in diabetes mellitus patients
Published in BMC gastroenterology (21-10-2015)“…Helicobacter pylori infection is the most important risk factor for gastric cancer, for which eradication therapy is commonly performed. However, gastric…”
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Nationwide analysis of antimicrobial resistance in pathogenic Escherichia coli strains isolated from diseased swine over 29 years in Japan
Published in Frontiers in microbiology (17-03-2023)“…Pathogenic strains are important causes of several swine diseases that result in significant economic losses worldwide. In Japan, the use of antimicrobials in…”
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Effects of adiponectin on growth and differentiation of human keratinocytes—Implication of impaired wound healing in diabetes
Published in Biochemical and biophysical research communications (19-09-2008)“…Impaired wound healing is one of the most common complications associated with diabetes. Adiponectin is an abundant circulating adipocyte-derived cytokine that…”
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Prognostic significance of preoperative 18F-FDG PET/CT for breast cancer subtypes
Published in Breast (Edinburgh) (01-12-2016)“…Adjuvant treatments for operable breast cancers are determined according to subtypes defined based on estrogen receptor (ER) and human epidermal growth factor…”
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Identification of a Recently Dominant Sublineage in Salmonella 4,[5],12:i:- Sequence Type 34 Isolated From Food Animals in Japan
Published in Frontiers in microbiology (01-07-2021)“…Salmonella enterica subsp. enterica serovar Typhimurium sequence type 34 (ST34) and its monophasic variant ( Salmonella 4,[5],12:i:-) are among the most…”
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Influence of Helicobacter pylori eradication on the management of type 2 diabetes
Published in Hepato-gastroenterology (01-03-2012)“…H. pylori eradication therapy has been widely performed. In addition, the number of patients with type 2 diabetes is increasing worldwide. The aim of this…”
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