Search Results - "YAN ZHONG"
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1
Enantioselective radical conjugate additions driven by a photoactive intramolecular iminium-ion-based EDA complex
Published in Nature communications (16-08-2018)“…The photochemical activity of electron donor–acceptor (EDA) complexes provides a way to generate radicals under mild conditions. This strategy has found…”
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2
Development of Synthetic Methodologies via Catalytic Enantioselective Synthesis of 3,3-Disubstituted Oxindoles
Published in Accounts of chemical research (19-06-2018)“…Conspectus 3,3-Disubstituted oxindoles are widely distributed in natural products, drugs, and pharmaceutically active compounds. The absolute configuration and…”
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3
Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters
Published in Chemical reviews (22-06-2016)“…This Review summarizes the advances in the construction of all-carbon quaternary stereocenters via catalytic enantioselective desymmetrization of prochiral and…”
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4
Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities
Published in Cell death and differentiation (01-02-2021)“…Neurodegenerative diseases are characterised by progressive damage to the nervous system including the selective loss of vulnerable populations of neurons…”
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5
Atomically Thin Arsenene and Antimonene: Semimetal-Semiconductor and Indirect-Direct Band-Gap Transitions
Published in Angewandte Chemie International Edition (02-03-2015)“…The typical two‐dimensional (2D) semiconductors MoS2, MoSe2, WS2, WSe2 and black phosphorus have garnered tremendous interest for their unique electronic,…”
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6
Visible‐Light Photocatalysis of Asymmetric [2+2] Cycloaddition in Cage‐Confined Nanospace Merging Chirality with Triplet‐State Photosensitization
Published in Angewandte Chemie International Edition (25-05-2020)“…Although the photodimerization of acenaphthylene (ACE) has been known for 100 years, the asymmetric cycloaddition of its 1‐substituted derivatives is unknown…”
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7
Ferroptosis‐Enhanced Cancer Immunity by a Ferrocene‐Appended Iridium(III) Diphosphine Complex
Published in Angewandte Chemie International Edition (11-04-2022)“…Ferroptosis is a programmed cell death pathway discovered in recent years, and ferroptosis‐inducing agents have great potential as new antitumor candidates…”
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8
Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters
Published in ACS catalysis (01-03-2019)“…The catalytic enantioselective assembly of spirocyclic molecules featuring a spiro quaternary carbon stereocenter is currently of great interest because such…”
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9
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
Published in Cell death & disease (05-05-2021)“…Ischaemic stroke is becoming the most common cerebral disease in aging populations, but the underlying molecular mechanism of the disease has not yet been…”
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10
Copper‐Catalyzed Remote Direct Thiocyanation of Alkyl C(sp3)−H Bonds
Published in Advanced synthesis & catalysis (21-09-2020)“…A method for site‐selective intermolecular C(sp3)−H thiocyanation of aliphatic sulfonamides is developed using cheap trimethylsilyl isothiocyanate (TMSNCS) as…”
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11
Highly Stereoselective Gold‐Catalyzed Coupling of Diazo Reagents and Fluorinated Enol Silyl Ethers to Tetrasubstituted Alkenes
Published in Angewandte Chemie International Edition (20-02-2017)“…We report a highly stereoselective synthesis of all‐carbon or fluorinated tetrasubstituted alkenes from diazo reagents and fluorinated enol silyl ethers, using…”
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12
2D materials via liquid exfoliation: a review on fabrication and applications
Published in Science bulletin (Beijing) (01-12-2015)“…Since graphene was discovered, the study of two-dimensional (2D) materials with atomic thickness has become a hot spot. To prepare different 2D materials,…”
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13
Physical exercise: An inducer of positive oxidative stress in skeletal muscle aging
Published in Life sciences (1973) (01-07-2020)“…Oxidative stress is the core of most pathological situations, and its attribution toward disease conversion is not yet well established. The adaptive capacity…”
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14
Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones
Published in Nature communications (20-11-2017)“…Optically active spirocyclic compounds play an important role in drug discovery, and new synthetic strategies for the efficient generation of spiro…”
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15
Regio‐ and Enantioselective Photodimerization within the Confined Space of a Homochiral Ruthenium/Palladium Heterometallic Coordination Cage
Published in Angewandte Chemie International Edition (27-03-2017)“…The photoinduced regio‐ and enantioselective coupling of naphthols and derivatives thereof is achieved in the confined chiral coordination space of a RuII…”
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16
Activating Pronucleophiles with High pKa Values: Chiral Organo‐Superbases
Published in Angewandte Chemie International Edition (18-05-2020)“…Direct deprotonation represents an extremely simple, straightforward, and atom‐economic strategy to activate pronucleophiles bearing an acidic proton. However,…”
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17
Highly stereoselective olefin cyclopropanation of diazooxindoles catalyzed by a C2-symmetric spiroketal bisphosphine/Au(I) complex
Published in Journal of the American Chemical Society (05-06-2013)“…A spiroketal bisphosphine (SKP) derived chiral digold complex is identified as a powerful catalyst for the highly diastereo- and enantioselective synthesis of…”
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18
Dearomative 1,4-difunctionalization of naphthalenes via palladium-catalyzed tandem Heck/Suzuki coupling reaction
Published in Nature communications (01-09-2020)“…Dearomative functionalization reactions represent an important strategy for the synthesis of valuable three-dimensional molecules from simple planar aromatics…”
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19
Recent Advances in Developing Radical Methods for the Synthesis of Aliphatic Sulfonyl Fluorides
Published in European journal of organic chemistry (17-06-2024)“…Sulfonyl fluorides have widespread applications in many fields, including organic synthesis, chemical biology, drug discovery and materials science. In…”
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20
Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice
Published in ACS nano (22-05-2018)“…Excess iron deposition in the brain often causes oxidative stress-related damage and necrosis of dopaminergic neurons in the substantia nigra and has been…”
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