Search Results - "YAMAZAKI, Naomi"
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Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression
Published in The Journal of neuroscience (21-09-2016)“…Intraneuronal calcium stimulates the calpain-dependent conversion of p35 to p25, a CDK5 activator. It is widely believed that amyloid β peptide (Aβ) induces…”
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Electron Mobility in a Mercury-mediated Duplex of Triazole-linked DNA (TLDNA)
Published in Chemistry letters (05-03-2011)“…A metal-ion-mediated duplex of triazole-linked DNA (TLDNA) was synthesized via thymine–mercury(II)–thymine (T–Hg–T) base pairing. The electron-transport…”
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Synthesis of Triazole-linked Analogues of RNA (TLRNA)
Published in Chemistry letters (2012)“…A triazole-linked analogue of RNA (TLRNA) has been developed. Monomeric ribonucleoside analogues bearing natural nucleobases were prepared from D-xylose to…”
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Triazole-Linked DNA as a Primer Surrogate in the Synthesis of First-Strand cDNA
Published in Chemistry, an Asian journal (04-11-2011)“…A phosphate‐eliminated nonnatural oligonucleotide serves as a primer surrogate in reverse transcription reaction of mRNA. Despite of the nonnatural triazole…”
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Antioxidant Activity of Hydroxyflavonoids
Published in Journal of Health Science (2005)“…The antioxidant activity of 28 natural and synthetic hydroxyflavonoids was estimated through the 1,1-diphenyl-2-picrylhyrazyl (DPPH) radical, superoxide…”
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Triazole-linked analogue of deoxyribonucleic acid ((TL)DNA): design, synthesis, and double-strand formation with natural DNA
Published in Organic letters (04-09-2008)“…A new triazole-linked analogue of DNA ((TL)DNA) has been designed and synthesized using click chemistry. The chain elongation reaction using copper-catalyzed…”
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Triazole-Linked Analogue of Deoxyribonucleic Acid (TLDNA): Design, Synthesis, and Double-Strand Formation with Natural DNA
Published in Organic letters (04-09-2008)“…A new triazole-linked analogue of DNA (TLDNA) has been designed and synthesized using click chemistry. The chain elongation reaction using copper-catalyzed…”
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Convergent synthesis of oligomers of triazole-linked DNA analogue ( super(TL)DNA) in solution phase
Published in Tetrahedron letters (15-07-2009)“…A convergent route for the solution-phase synthesis of oligomeric triazole-linked analogues of DNA ( super(TL)DNA) has been developed. A one-pot procedure for…”
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Convergent synthesis of oligomers of triazole-linked DNA analogue ( TLDNA) in solution phase
Published in Tetrahedron letters (15-07-2009)“…A convergent route for the solution-phase synthesis of oligomeric triazole-linked analogues of DNA ( TLDNA) has been developed. A one-pot procedure for…”
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Efficient and improved synthesis of triazole-linked DNA (TLDNA) oligomers
Published in Tetrahedron letters (15-02-2012)“…A method for the synthesis of triazole-linked DNA oligomers has been revisited to incorporate a reliable protective group and linker for solid-phase synthesis…”
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P1-113: Accecelerated Aβ plaque formation by low level expression of presenilin-1 with R278I mutation in knock-in mouse
Published in Alzheimer's & dementia (01-07-2008)Get full text
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Chemical and Chemotaxonomical Studies of Filices. XLVII. Chemical Studies on the Constituents of Arachniodes nigrospinosa (CHING) CHING, A. festina (HANCE) CHING and A. mutica OHWI
Published in Chemical & pharmaceutical bulletin (1984)“…Two new compounds, II and III, were isolated, together with 4-hydroxynicotinamide, from the fronds of both Arachniodes nigrospinosa and A. festina. The…”
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New sublines of Chinese hamster CHL stably expressing human NAT1 or NAT2 N-acetyltransferases of Salmonella typhimurium O-acetyltransferase : comparison of the sensitivities to nitroarenes and aromatic amines using the in vitro micronucleus test
Published in Cancer research (Chicago, Ill.) (01-04-1994)“…New sublines of Chinese hamster CHL cells stably expressing human NAT1 or NAT2 N-acetyltransferases or O-acetyltransferase of Salmonella typhimurium were…”
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Immunological Study of Late Cerebral Vasospasm in Subarachnoid Hemorrhage
Published in Neurologia medico-chirurgica (1982)“…Using immunological studies, it was investigated whether any vasoactive substances were produced in the subarachnoid space and whether these substances…”
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Immunological Investigation of Brain Tumor Patients
Published in Neurologia medico-chirurgica (1976)“…Patients with malignant tumor have immunological reaction to the tumor cells, but the reaction is suppresed with the growth of the tumor. For the clinical…”
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