Search Results - "YAMASOBA, Tatsuya"

Dizziness and Imbalance in the Elderly: Age-related Decline in the Vestibular System by Iwasaki, Shinichi, Yamasoba, Tatsuya

“…Dizziness and imbalance are amongst the most common complaints in older people, and are a growing public health concern since they put older people at a…”
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Oxidative Stresses and Mitochondrial Dysfunction in Age-Related Hearing Loss by Fujimoto, Chisato, Yamasoba, Tatsuya

“…Age-related hearing loss (ARHL), the progressive loss of hearing associated with aging, is the most common sensory disorder in the elderly population. The…”
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Reactive Oxygen Species, Apoptosis, and Mitochondrial Dysfunction in Hearing Loss by Kamogashira, Teru, Yamasoba, Tatsuya, Fujimoto, Chisato

“…Reactive oxygen species (ROS) production is involved in several apoptotic and necrotic cell death pathways in auditory tissues. These pathways are the major…”
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Mitochondria-Targeted Antioxidants for Treatment of Hearing Loss: A Systematic Review by Fujimoto, Chisato, Yamasoba, Tatsuya

“…Mitochondrial dysfunction is associated with the etiologies of sensorineural hearing loss, such as age-related hearing loss, noise- and ototoxic drug-induced…”
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Age-Related Olfactory Dysfunction: Epidemiology, Pathophysiology, and Clinical Management by Kondo, Kenji, Kikuta, Shu, Ueha, Rumi, Suzukawa, Keigo, Yamasoba, Tatsuya

“…As other sensory systems, olfactory function deteriorates with age. Epidemiological studies have revealed that the incidence of olfactory dysfunction increases…”
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Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles by Baba, Miyuki, Itaka, Keiji, Kondo, Kenji, Yamasoba, Tatsuya, Kataoka, Kazunori

“…Sensory nerve disorders are difficult to cure completely considering poor nerve regeneration capacity and difficulties in accurately targeting neural tissues…”
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Current concepts in age-related hearing loss: Epidemiology and mechanistic pathways by Yamasoba, Tatsuya, Lin, Frank R., Someya, Shinichi, Kashio, Akinori, Sakamoto, Takashi, Kondo, Kenji

“…Age-related hearing loss (AHL), also known as presbycusis, is a universal feature of mammalian aging and is characterized by a decline of auditory function,…”
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Application of Machine Learning to Predict Hearing Outcomes of Tympanoplasty by Koyama, Hajime, Kashio, Akinori, Uranaka, Tsukasa, Matsumoto, Yu, Yamasoba, Tatsuya

“…Objective This retrospective study aimed to evaluate the performance of machine learning techniques in predicting air‐bone gap after tympanoplasty compared…”
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Translational Nanomedicine Boosts Anti-PD1 Therapy to Eradicate Orthotopic PTEN-Negative Glioblastoma by Kinoh, Hiroaki, Quader, Sabina, Shibasaki, Hitoshi, Liu, Xueying, Maity, Amit, Yamasoba, Tatsuya, Cabral, Horacio, Kataoka, Kazunori

“…Glioblastoma (GBM) is resistant to immune checkpoint inhibition due to its low mutation rate, phosphatase and tensin homologue (PTEN)-deficient…”
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Expression of ACE2 and TMPRSS2 Proteins in the Upper and Lower Aerodigestive Tracts of Rats: Implications on COVID 19 Infections by Sato, Taku, Ueha, Rumi, Goto, Takao, Yamauchi, Akihito, Kondo, Kenji, Yamasoba, Tatsuya

“…Objective Patients with coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), exhibit not only…”
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Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit by Kishimoto-Urata, Megumi, Urata, Shinji, Kagoya, Ryoji, Imamura, Fumiaki, Nagayama, Shin, Reyna, Rachel A., Maruyama, Junki, Yamasoba, Tatsuya, Kondo, Kenji, Hasegawa-Ishii, Sanae, Paessler, Slobodan

“…The impact of SARS-CoV-2 on the olfactory pathway was studied over several time points using Syrian golden hamsters. We found an incomplete recovery of the…”
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Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers by Ando, Mizuo, Saito, Yuki, Xu, Guorong, Bui, Nam Q., Medetgul-Ernar, Kate, Pu, Minya, Fisch, Kathleen, Ren, Shuling, Sakai, Akihiro, Fukusumi, Takahito, Liu, Chao, Haft, Sunny, Pang, John, Mark, Adam, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Yegnasubramanian, Srinivasan, Fertig, Elana J., Ha, Patrick, Tamayo, Pablo, Yamasoba, Tatsuya, Ideker, Trey, Messer, Karen, Califano, Joseph A.

“…Although promoter-associated CpG islands have been established as targets of DNA methylation changes in cancer, previous studies suggest that epigenetic…”
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Noisy galvanic vestibular stimulation induces a sustained improvement in body balance in elderly adults by Fujimoto, Chisato, Yamamoto, Yoshiharu, Kamogashira, Teru, Kinoshita, Makoto, Egami, Naoya, Uemura, Yukari, Togo, Fumiharu, Yamasoba, Tatsuya, Iwasaki, Shinichi

“…Vestibular dysfunction causes postural instability, which is prevalent in the elderly. We previously showed that an imperceptible level of noisy galvanic…”
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Usefulness of circulating tumor DNA by targeting human papilloma virus-derived sequences as a biomarker in p16-positive oropharyngeal cancer by Akashi, Ken, Sakai, Toshihiko, Fukuoka, Osamu, Saito, Yuki, Yoshida, Masafumi, Ando, Mizuo, Ito, Takeshi, Murakami, Yoshinori, Yamasoba, Tatsuya

“…In head and neck cancer, early detection of recurrence after treatment is important. The contemporary development of therapeutic agents have improved the…”
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Effects of pyrroloquinoline quinone on noise-induced and age-related hearing loss in mice by Gao, Ying, Kamogashira, Teru, Fujimoto, Chisato, Iwasaki, Shinichi, Yamasoba, Tatsuya

“…We investigated whether the oxidoreductase cofactor pyrroloquinoline quinone (PQQ) prevents noise-induced and age-related hearing loss (NIHL and ARHL) in mice…”
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Pure Skin Perforator Flaps: The Anatomical Vascularity of the Superthin Flap by Narushima, Mitsunaga, Yamasoba, Tatsuya, Iida, Takuya, Matsumoto, Yu, Yamamoto, Takumi, Yoshimatsu, Hidehiko, Timothy, Shim, Pafitanis, Georgios, Yamashita, Shuji, Koshima, Isao

“…Recently, a superthin "pure skin perforator" flap without any subcutaneous tissue was proposed, but the vascularity is still unclear. The authors therefore…”
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Role of Oxidative Stress and Antioxidants in Acquired Inner Ear Disorders by Kishimoto-Urata, Megumi, Urata, Shinji, Fujimoto, Chisato, Yamasoba, Tatsuya

“…Oxygen metabolism in the mitochondria is essential for biological activity, and reactive oxygen species (ROS) are produced simultaneously in the cell. Once an…”
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Activation of the PGE2–EP2 pathway as a potential drug target for treating eosinophilic rhinosinusitis by Horikiri, Kyohei, Taketomi, Yoshitaka, Kondo, Kenji, Yamasoba, Tatsuya, Murakami, Makoto

“…Current treatments of eosinophilic chronic rhinosinusitis (ECRS) involve corticosteroids with various adverse effects and costly therapies such as dupilumab,…”
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Complication rates after functional endoscopic sinus surgery: Analysis of 50,734 Japanese patients by Suzuki, Sayaka, Yasunaga, Hideo, Matsui, Hiroki, Fushimi, Kiyohide, Kondo, Kenji, Yamasoba, Tatsuya

“…Objective The complication rates associated with different types of functional endoscopic sinus surgery (FESS) remain to be fully examined. Study Design…”
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Zone-specific damage of the olfactory epithelium under protein restriction by Tuerdi, Ayinuer, Kikuta, Shu, Kinoshita, Makoto, Kamogashira, Teru, Kondo, Kenji, Yamasoba, Tatsuya

“…Oxidative stress causes tissue damage, affecting age-related pathologies. Protein restriction (PR) provides a powerful intervention strategy for reducing…”
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