Search Results - "YAMANAKA, Kunitoshi"
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Inhibitory effects of Myricetin derivatives on curli-dependent biofilm formation in Escherichia coli
Published in Scientific reports (31-05-2018)“…Biofilms are well-organised communities of microbes embedded in a self-produced extracellular matrix (e.g., curli amyloid fibers) and are associated with…”
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Novel strategy for biofilm inhibition by using small molecules targeting molecular chaperone DnaK
Published in Antimicrobial agents and chemotherapy (01-01-2015)“…Biofilms are complex communities of microorganisms that attach to surfaces and are embedded in a self-produced extracellular matrix. Since these cells acquire…”
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Hierarchical Model for the Role of J-Domain Proteins in Distinct Cellular Functions
Published in Journal of molecular biology (05-02-2021)“…[Display omitted] •The specific role of JDPs in bacterial cellular functions is unclear.•DnaJ, one of the JDPs in E. coli, is essential for survival at high…”
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Functional characterization of UBXN-6, a C-terminal cofactor of CDC-48, in C. elegans
Published in Biochemical and biophysical research communications (05-02-2019)“…CDC-48 is a AAA (ATPases associated with diverse cellular activities) chaperone and participates in a wide range of cellular activities. Its functional…”
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Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans
Published in Biochemical and biophysical research communications (27-03-2015)“…CDC-48 (also called VCP or p97 in mammals and Cdc48p in yeast) is a AAA (ATPases associated with diverse cellular activities) chaperone and participates in a…”
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Positive Cooperativity of the p97 AAA ATPase Is Critical for Essential Functions
Published in The Journal of biological chemistry (06-05-2011)“…p97 is composed of two conserved AAA (ATPases associated with diverse cellular activities) domains, which form a tandem hexameric ring. We characterized the…”
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Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening
Published in Scientific reports (14-12-2018)“…Familial amyloid polyneuropathy is a hereditary systemic amyloidosis caused by a mutation in the transthyretin (TTR) gene. Amyloid deposits in tissues of…”
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AAA+ Chaperone ClpX Regulates Dynamics of Prokaryotic Cytoskeletal Protein FtsZ
Published in The Journal of biological chemistry (26-02-2010)“…AAA+ chaperone ClpX has been suggested to be a modulator of prokaryotic cytoskeletal protein FtsZ, but the details of recognition and remodeling of FtsZ by…”
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Multitasking of Hsp70 chaperone in the biogenesis of bacterial functional amyloids
Published in Communications biology (31-05-2018)“…Biofilms are intricate communities of microorganisms embedded in a self-produced matrix of extracellular polymer, which provides microbes survival advantages…”
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Mild electrical stimulation increases stress resistance and suppresses fat accumulation via activation of LKB1-AMPK signaling pathway in C. elegans
Published in PloS one (09-12-2014)“…Electrical current at physiological strength has been applied as a therapeutic approach for various diseases. Several of our works showed that mild electrical…”
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CDC-48/p97 is required for proper meiotic chromosome segregation via controlling AIR-2/Aurora B kinase localization in Caenorhabditis elegans
Published in Journal of structural biology (01-08-2012)“…CDC-48/p97 is a AAA (ATPases associated with diverse cellular activities) chaperone involved in protein conformational changes such as the disassembly of…”
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ER E3 ubiquitin ligase HRD‐1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in Caenorhabditis elegans
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-09-2007)“…p97 (also called VCP or Cdc48p) and E3 ubiquitin ligases are the key players in retrotranslocation and ubiquitination of substrates in the endoplasmic…”
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The CspA family in Escherichia coli : multiple gene duplication for stress adaptation
Published in Molecular microbiology (01-01-1998)“…CspA was originally found as the major cold‐shock protein in Escherichia coli, consisting of 70‐amino‐acid residues. It forms a β‐barrel structure with five…”
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Selective mRNA Degradation by Polynucleotide Phosphorylase in Cold Shock Adaptation in Escherichia coli
Published in Journal of Bacteriology (01-05-2001)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Conserved Pore Residues in the AAA Protease FtsH Are Important for Proteolysis and Its Coupling to ATP Hydrolysis
Published in The Journal of biological chemistry (12-12-2003)“…Like other AAA proteins, Escherichia coli FtsH, a membrane-bound AAA protease, contains highly conserved aromatic and glycine residues (Phe228 and Gly230) that…”
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p97 homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-08-2008)“…Polyglutamine (polyQ)-expanded proteins are associated with cytotoxicity in some neurodegenerative disorders such as Huntington's disease. We have reported…”
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Caenorhabditis elegans UBX cofactors for CDC-48/p97 control spermatogenesis
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-12-2010)“…UBX (ubiquitin regulatory X) domain-containing proteins act as cofactors for CDC-48/p97. CDC-48/p97 is essential for various cellular processes including…”
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Caenorhabditis elegans p97 controls germline-specific sex determination by controlling the TRA-1 level in a CUL-2-dependent manner
Published in Journal of cell science (15-10-2009)“…p97 (CDC-48 in Caenorhabditis elegans) is a ubiquitin-selective AAA (ATPases associated with diverse cellular activities) chaperone and its key function is to…”
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Successful leukocytapheresis therapy in a patient with rheumatoid arthritis on maintenance hemodialysis
Published in Modern rheumatology (01-01-2015)“…Abstract We report the case of a 44-year-old female undergoing maintenance hemodialysis in whom early-phase rheumatoid arthritis (RA) was successfully treated…”
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Single oral dose of geranylgeranylacetone induces heat-shock protein 72 and renders protection against ischemia/reperfusion injury in rat heart
Published in Circulation (New York, N.Y.) (09-10-2001)“…Induction of heat-shock proteins (HSPs) results in cardioprotection against ischemic insult. Geranylgeranylacetone (GGA), known as an antiulcer agent,…”
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