Search Results - "YAMADA, Yoshihisa"

Potential Efficacy of Proteasome Inhibitor, Delanzomib, for the Treatment of Renal Fibrosis by Sawa-Aihara, Ayano, Hattori, Katsuji, Nagao, Goshi, Yamada, Yoshihisa, Ishida, Tatsuhiro

“…Renal fibrosis is scarring and tissue hardening caused by the excess deposition of extracellular matrix proteins in response to chronic inflammation. Renal…”
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Mobilized Muse Cells After Acute Myocardial Infarction Predict Cardiac Function and Remodeling in the Chronic Phase by Tanaka, Toshiki, Nishigaki, Kazuhiko, Minatoguchi, Shingo, Nawa, Takahide, Yamada, Yoshihisa, Kanamori, Hiromitsu, Mikami, Atsushi, Ushikoshi, Hiroaki, Kawasaki, Masanori, Dezawa, Mari, Minatoguchi, Shinya

“…Background:Multilineage differentiating stress-enduring (Muse) cells are SSEA3+and CD105+double-positive pluripotent-like stem cells. We aimed to examine the…”
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S1P-S1PR2 Axis Mediates Homing of Muse Cells into Damaged Heart for Long Lasting Tissue Repair and Functional Recovery After Acute Myocardial Infarction by Yamada, Yoshihisa, Wakao, Shohei, Kushida, Yoshihiro, Minatoguchi, Shingo, Mikami, Atsushi, Higashi, Kenshi, Baba, Shinya, Shigemoto, Taeko, Kuroda, Yasumasa, Kanamori, Hiromitsu, Amin, Mohamad, Kawasaki, Masanori, Nishigaki, Kazuhiko, Taoka, Masato, Isobe, Toshiaki, Muramatsu, Chisako, Dezawa, Mari, Minatoguchi, Shinya

“…RATIONALE:Muse cells, pluripotent marker SSEA-3 cells, are non-tumorigenic endogenous pluripotent-like stem cells obtainable from various tissues including the…”
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Stem cell therapy for acute myocardial infarction - focusing on the comparison between Muse cells and mesenchymal stem cells by Yamada, Yoshihisa, Minatoguchi, Shingo, Kanamori, Hiromitsu, Mikami, Atsushi, Okura, Hiroyuki, Dezawa, Mari, Minatoguchi, Shinya

“…•Bone marrow mononuclear cells (BM-MNCs) and bone marrow mesenchymal stem cells (BM-MSCs) have been used in stem cell therapy for acute myocardial infarction…”
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Human Muse cells reduce myocardial infarct size and improve cardiac function without causing arrythmias in a swine model of acute myocardial infarction by Yamada, Yoshihisa, Minatoguchi, Shingo, Baba, Shinya, Shibata, Sanae, Takashima, Satoshi, Wakao, Shohei, Okura, Hiroyuki, Dezawa, Mari, Minatoguchi, Shinya

“…We recently reported that multilineage-differentiating stress enduring (Muse) cells intravenously administered after acute myocardial infarction (AMI),…”
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In vitro and in vivo pharmacological profile of OPC-61815, a water-soluble phosphate ester pro-drug of tolvaptan by Fujiki, Hiroyuki, Matsunaga, Masayuki, Furukawa, Masayuki, Yamashita, Tatsuya, Nakamura, Shigeki, Miyazaki, Toshiki, Mizuguchi, Hiroshi, Menjo, Yasuhiro, Matsuda, Takakuni, Yamada, Yoshihisa

“…Tolvaptan is an orally active vasopressin V2 receptor antagonist and used for the treatment of volume overload in some disease as an aquaretic. Tolvaptan…”
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Effects of progranulin on the pathological conditions in experimental myocardial infarction model by Sasaki, Takahiro, Shimazawa, Masamitsu, Kanamori, Hiromitsu, Yamada, Yoshihisa, Nishinaka, Anri, Kuse, Yoshiki, Suzuki, Genjiro, Masuda, Tomomi, Nakamura, Shinsuke, Hosokawa, Masato, Minatoguchi, Shinya, Hara, Hideaki

“…Progranulin is a secreted growth factor associated with multiple physiological functions in ischemic pathophysiology. However, it is still not fully understood…”
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MicroRNA-145 repairs infarcted myocardium by accelerating cardiomyocyte autophagy by Higashi, Kenshi, Yamada, Yoshihisa, Minatoguchi, Shingo, Baba, Shinya, Iwasa, Masamitsu, Kanamori, Hiromitsu, Kawasaki, Masanori, Nishigaki, Kazuhiko, Takemura, Genzou, Kumazaki, Minami, Akao, Yukihiro, Minatoguchi, Shinya

“…We investigated whether microRNA-145 (miR-145) has a cardioprotective effect in a rabbit model of myocardial infarction (MI) and in H9c2 rat cardiomyoblasts…”
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International Society of Nephrology first consensus guidance for preclinical animal studies in translational nephrology by Nangaku, Masaomi, Kitching, A Richard, Boor, Peter, Fornoni, Alessia, Floege, Jürgen, Coates, P Toby, Himmelfarb, Jonathan, Lennon, Rachel, Anders, Hans-Joachim, Humphreys, Benjamin D, Caskey, Fergus J, Fogo, Agnes B

“…Preclinical tests in animal models are key steps in early drug development. Consequently, the International Society of Nephrology held a consensus meeting that…”
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Morphological characteristics in diabetic cardiomyopathy associated with autophagy by Kanamori, Hiromitsu, Naruse, Genki, Yoshida, Akihiro, Minatoguchi, Shingo, Watanabe, Takatomo, Kawaguchi, Tomonori, Tanaka, Toshiki, Yamada, Yoshihisa, Takasugi, Hironobu, Mikami, Atsushi, Minatoguchi, Shinya, Miyazaki, Tatsuhiko, Okura, Hiroyuki

“…•Diabetic cardiomyopathy develops in the absence of coronary artery disease or hypertension.•Morphological features provide new insight into the…”
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Evaluation of retinal blood flow before and after panretinal photocoagulation using pattern scan laser for diabetic retinopathy by Yamada, Yoshihisa, Suzuma, Kiyoshi, Onizuka, Naoko, Uematsu, Masafumi, Mohamed, Yasser Helmy, Kitaoka, Takashi

“…Purpose: Laser speckle flowgraphy (LSFG) can measure blood flow in the ocular fundus. We analyzed the relationship between retinal blood flow and panretinal…”
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High-salt intake accelerates functional and histological renal damage associated with renal tissue overexpression of (pro)renin receptors and AT1 receptors in spontaneously hypertensive rats by Hayakawa, Yuka, Komaki, Hisaaki, Minatoguchi, Shingo, Yamada, Yoshihisa, Kanamori, Hiromitsu, Nishigaki, Kazuhiko, Minatoguchi, Shinya

“…Objective This study aimed to investigate the effect of combination of high-salt intake and hypertension on renal functional and histological damage,…”
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Increased Plasma Adenosine Concentration in the Subacute Phase May Contribute to Attenuation of Left Ventricular Dilation in the Chronic Phase in Patients With Acute Myocardial Infarction by Hatasa, Masanori, Tanaka, Toshiki, Minatoguchi, Shingo, Yamada, Yoshihisa, Kanamori, Hiromitsu, Kawasaki, Masanori, Nishigaki, Kazuhiko, Esaka, Yukihiro, Uno, Bunji, Minatoguchi, Shinya

“…Background: Changes in the plasma adenosine concentration and the effects on left ventricular (LV) function and remodeling in patients with acute myocardial…”
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High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension by Hayakawa, Yuka, Aoyama, Takuma, Yokoyama, Chiharu, Okamoto, Chihiro, Komaki, Hisaaki, Minatoguchi, Shingo, Iwasa, Masamitsu, Yamada, Yoshihisa, Kawamura, Itta, Kawasaki, Masanori, Nishigaki, Kazuhiko, Mikami, Atsushi, Suzuki, Fumiaki, Minatoguchi, Shinya

“…It has not yet been fully elucidated whether cardiac tissue levels of prorenin, renin and (P)RR are activated in hypertension with a high salt intake. We…”
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Excessively low salt diet damages the heart through activation of cardiac (pro) renin receptor, renin-angiotensin-aldosterone, and sympatho-adrenal systems in spontaneously hypertensive rats by Okamoto, Chihiro, Hayakawa, Yuka, Aoyama, Takuma, Komaki, Hisaaki, Minatoguchi, Shingo, Iwasa, Masamitsu, Yamada, Yoshihisa, Kanamori, Hiromitsu, Kawasaki, Masanori, Nishigaki, Kazuhiko, Mikami, Atsushi, Minatoguchi, Shinya

“…A high salt intake causes hypertension and leads to cardiovascular disease. Therefore, a low salt diet is now recommended to prevent hypertension and…”
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Increased expression and activation of cathepsin K in human osteoarthritic cartilage and synovial tissues by Kozawa, Eiji, Cheng, Xian Wu, Urakawa, Hiroshi, Arai, Eisuke, Yamada, Yoshihisa, Kitamura, Shinji, Sato, Koji, Kuzuya, Masafumi, Ishiguro, Naoki, Nishida, Yoshihiro

“…ABSTRACT Few studies have analyzed Cathepsin K (CatK) expression in human osteoarthritic tissues. We investigated CatK expression and activation in human…”
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Azilsartan attenuates cardiac damage caused by high salt intake through the downregulation of the cardiac (pro)renin receptor and its downstream signals in spontaneously hypertensive rats by Komaki, Hisaaki, Iwasa, Masamitsu, Hayakawa, Yuka, Okamoto, Chihiro, Minatoguchi, Shingo, Yamada, Yoshihisa, Kanamori, Hiromitsu, Kawasaki, Masanori, Nishigaki, Kazuhiko, Minatoguchi, Shinya

“…We examined whether the stimulation of the angiotensin II AT1 receptor increases the expression of the cardiac (pro)renin receptor ((P)RR) and its downstream…”
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Endogenous Adenosine May Be Related to Left Ventricular Dysfunction, Dilation, and Wall Thinning in Patients With Heart Disease by Kinomura, Yujiro, Tanaka, Toshiki, Aoyama, Takuma, Hatasa, Masanori, Minatoguchi, Shingo, Iwasa, Masamitsu, Yamada, Yoshihisa, Nawa, Takahide, Kanamori, Hiromitsu, Kawasaki, Masanori, Esaka, Yukihiro, Uno, Bunji, Nishigaki, Kazuhiko, Minatoguchi, Shinya

“…Background:The role of endogenous adenosine in cardiac patients is still unclear, so we investigated the relationship between the plasma adenosine…”
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Clinical Outcome of Sacral Chordoma With Carbon Ion Radiotherapy Compared With Surgery by Nishida, Yoshihiro, M.D, Kamada, Tadashi, M.D, Imai, Reiko, M.D, Tsukushi, Satoshi, M.D, Yamada, Yoshihisa, M.D, Sugiura, Hideshi, M.D, Shido, Yoji, M.D, Wasa, Junji, M.D, Ishiguro, Naoki, M.D

“…Purpose To evaluate the efficacy, post-treatment function, toxicity, and complications of carbon ion radiotherapy (RT) for sacral chordoma compared with…”
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Salmon milt DNA as a template for the mass production of Ag nanoparticles by Takeshima, Tomomi, Sun, Ling, Wang, Yanqing, Yamada, Yoshihisa, Nishi, Norio, Yonezawa, Tetsu, Fugetsu, Bunshi

“…A wet-chemical approach using DNA extracted from salmon milt as a template to mass produce Ag nanoparticles was developed. Spherical Ag nanoparticles with a…”
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