Search Results - "YAM, Lung T"

Biology and Clinical Significance of Tartrate-Resistant Acid Phosphatases: New Perspectives on an Old Enzyme by Janckila, Anthony J., Yam, Lung T.

“…Type 5 tartrate-resistant acid phosphatase (TRAP) has been a clinically relevant biomarker for about 50 years. It has always been a reliable and specific…”
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Significance of Serum TRACP in Rheumatoid Arthritis by Janckila, Anthony J, Neustadt, David H, Yam, Lung T

“…Human serum contains two related isoforms of TRACP: TRACP 5a and TRACP 5b. Serum TRACP 5a protein is increased in about one third of rheumatoid arthritis (RA)…”
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Tartrate-resistant acid phosphatase as an immunohistochemical marker for inflammatory macrophages by JANCKILA, Anthony J, SLONE, Stephen P, LEAR, Sheron C, MARTIN, Alvin, YAM, Lung T

“…Human serum contains 2 isoforms of type-5 tartrate-resistant acid phosphatase (TRACP): 5a and 5b. TRACP-5b is osteoclastic. Our goal was to determine if serum…”
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Properties and expression of human tartrate-resistant acid phosphatase isoform 5a by monocyte-derived cells by Janckila, Anthony J., Parthasarathy, Ranga N., Parthasarathy, Latha K., Seelan, Ratnam S., Hsueh, Yi‐Cheung, Rissanen, Jukka, Alatalo, Sari L., Halleen, Jussi M., Yam, Lung T.

“…Human serum tartrate‐resistant acid phosphatase exists as two enzyme isoforms (TRACP 5a and 5b), derived by differential, post‐translational processing of a…”
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Correlation between histomorphometric parameters of bone resorption and serum type 5b tartrate-resistant acid phosphatase in uremic patients on maintenance hemodialysis by Chu, Pauling, Chao, Tsu-Yi, Lin, Yuh-Feng, Janckila, Anthony J, Yam, Lung T

“…Serum tartrate-resistant acid phosphatase 5b (TRACP) is a new marker of potential clinical use to monitor osteoclastic activity and bone resorption rate. The…”
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Serum tartrate-resistant acid phosphatase 5b activity as a prognostic marker of survival in breast cancer with bone metastasis by Wu, Yi-Ying, Janckila, Anthony J, Ku, Chih-Hung, Yu, Cheng-Ping, Yu, Jyh-Cherng, Lee, Su-Hui, Liu, Hsin-Yi, Yam, Lung T, Chao, Tsu-Yi

“…Serum tartrate-resistant acid phosphatase 5b (TRACP 5b) activity is a marker of osteoclast number and is elevated in breast cancer (BC) patients with extensive…”
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Tartrate-Resistant Acid Phosphatase 5b is a Useful Serum Marker for Extensive Bone Metastasis in Breast Cancer Patients by CHAO, Tsu-Yi, YU, Jyh-Cherng, KU, Chih-Hung, CHEN, Mary M, LEE, Su-Huei, JANCKILA, Anthony J, YAM, Lung T

“…Purpose: Previous studies showed that serum tartrate-resistant acid phosphatase 5b (TRACP5b) activity was increased in 70% to 94% of breast cancer (BC)…”
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Naphthol‐ASBI Phosphate as a Preferred Substrate for Tartrate‐Resistant Acid Phosphatase Isoform 5b by Janckila, Anthony J., Takahashi, Karen, Sun, Susan Z., Yam, Lung T.

“…Tartrate‐resistant acid phosphatase (TRAP) isoform 5b is a potential serum marker for osteoclastic activity. Biochemical assays for serum TRAP activity with…”
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The Semiquantitative Bone Scintigraphy Index Correlates With Serum Tartrate-Resistant Acid Phosphatase Activity in Breast Cancer Patients With Bone Metastasis by Tsai, Shih-Hung, MD, Chen, Ching-Yuan, MD, Ku, Chih-Hung, PhD, Janckila, Anthony J., PhD, Yam, Lung T., MD, Yu, Jyh-Cherng, MD, Chuang, Kai-Wen, BSc, Chao, Tsu-Yi, MD, PhD

“…OBJECTIVE To determine if a correlation exists between the semiquantitative bone scintigraphy index (SQBSI) and serum tartrate-resistant acid phosphatase 5b…”
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Clinical Significance of Immunoassays for Type-5 Tartrate-resistant Acid Phosphatase by Nakasato, Yuri R, Janckila, Anthony J, Halleen, Jussi M, Vaananen, H. Kalervo, Walton, Stephanie P, Yam, Lung T

“…Tartrate-resistant acid phosphatase (TRAP; EC 3.1.3.2) is a product of osteoclasts and a biochemical marker of bone resorption rate. However, erythrocytes and…”
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Effects of calcitriol on type 5b tartrate-resistant acid phosphatase and interleukin-6 in secondary hyperparathyroidism by Lu, Kuo-Cheng, Tseng, Chin-Feng, Wu, Chia-Chao, Yeung, Lai-King, Chen, Jin-Shuen, Chao, Tsu-Yi, Janckila, Anthony J, Yam, Lung T, Chu, Pauling

“…Secondary hyperparathyroidism (SHP) is characterized by high bone turnover and elevated serum bone remodeling markers. Elevation of serum interleukin-6 (IL-6)…”
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Serum tartrate-resistant acid phosphatase isoform 5a (TRACP5a) as a potential risk marker in cardiovascular disease by Janckila, Anthony J., Lin, Hseun-Fu, Wu, Yi-Ying, Ku, Chih-Hung, Yang, Shih-Ping, Lin, Wei-Shiang, Lee, Su-Huei, Yam, Lung T., Chao, Tsu-Yi

“…This study was undertaken to determine the association between serum tartrate-resistant acid phosphatase 5a (TRACP5a) and cardiovascular disease (CVD) risk…”
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Tartrate-resistant acid phosphatase 5b as a serum marker of bone metastasis in breast cancer patients by Chao, Tsu-Yi, Ho, Ching-Liang, Lee, Su-Huei, Chen, Mary Mei-Ju, Janckila, Anthony, Yam, Lung T

“…Diagnosis and follow-up of bone metastases in breast cancer patients usually rely on symptoms and imaging studies. Tartrate-resistant acid phosphatase 5b…”
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Electrophoretic study of tartrate-resistant acid phosphatase isoforms in endstage renal disease and rheumatoid arthritis by Takahashi, Karen, Janckila, Anthony J., Sun, Susan Z., Lederer, Eleanor D., Ray, Prasun C., Yam, Lung T.

“…The objective of this study was to identify the isoform, type-5a or type-5b, responsible for increased tartrate-resistant acid phosphatase (TRAP) activity in…”
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Tartrate-resistant Acid Phosphatase Isoform 5b as Serum Marker for Osteoclastic Activity by Janckila, Anthony J, Takahashi, Karen, Sun, Susan Z, Yam, Lung T

“…Tartrate-resistant acid phosphatase (AcP) 5b is a marker of osteoclastic activity and bone resorption. Immunoassays for serum TRAcP may lack sensitivity and…”
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Applications and performance of monoclonal antibodies to human tartrate resistant acid phosphatase by Pradella, Silvia D. Potenziani, Slone, Stephen P., Wu, Yi-Ying, Chao, Tsu-Yi, Parthasarathy, Ranga N., Yam, Lung T., Janckila, Anthony J.

“…Tartrate-resistant acid phosphatase (TRACP) is an enzyme common to cells of the mononuclear phagocyte system and a clinically relevant biomarker for…”
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Serum tartrate-resistant acid phosphatase isoforms in rheumatoid arthritis by Janckila, Anthony J., Neustadt, David H., Nakasato, Yuri R., Halleen, Jussi M., Hentunen, Teuvo, Yam, Lung T.

“…Objectives: Our objective was to evaluate the significance and source of serum tartrate-resistant acid phosphatase (TRACP) in patients with rheumatoid…”
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Tartrate‐Resistant Acid Phosphatase (TRACP): A Personal Perspective by Yam, Lung T, Janckila, Anthony J

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Disease‐Specific Expression of Tartrate‐Resistant Acid Phosphatase Isoforms by Janckila, Anthony J, Nakasato, Yuri R, Neustadt, David H, Yam, Lung T

“…The association between elevated serum type 5 TRACP activity and metabolic bone diseases has been recognized for many years. However, serum type 5 TRACP exists…”
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Development of immunoassays for serum tartrate-resistant acid phosphatase isoform 5a by Chao, Tsu-Yi, Lee, Su-Huei, Chen, Mary M., Neustadt, David H., Chaudhry, Uzma A., Yam, Lung T., Janckila, Anthony J.

“…Serum tartrate-resistant acid phosphatase (TRACP) consists of 2 structurally related isoforms, TRACP 5a and 5b. TRACP 5b is from bone-resorbing osteoclasts…”
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