Search Results - "YAKUSHIJI, Emi"

Atorvastatin Reduces Circulating S100A12 Levels in Patients with Carotid Atherosclerotic Plaques - A Link with Plaque Inflammation by Komatsu, Tomohiro, Ayaori, Makoto, Uto-Kondo, Harumi, Hayashi, Katsumi, Tamura, Katsumi, Sato, Hiroki, Sasaki, Makoto, Nishida, Takafumi, Takiguchi, Shunichi, Yakushiji, Emi, Nakaya, Kazuhiro, Ikewaki, Katsunori

“…Aims: Inflammation is involved in various processes of atherosclerosis development. Serum C-reactive protein (CRP) levels, a predictor for cardiovascular risk,…”
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Proteasomal Inhibition Promotes ATP-Binding Cassette Transporter A1 (ABCA1) and ABCG1 Expression and Cholesterol Efflux From Macrophages In Vitro and In Vivo by Ogura, Masatsune, Ayaori, Makoto, Terao, Yoshio, Hisada, Tetsuya, Iizuka, Maki, Takiguchi, Shunichi, Uto-Kondo, Harumi, Yakushiji, Emi, Nakaya, Kazuhiro, Sasaki, Makoto, Komatsu, Tomohiro, Ozasa, Hideki, Ohsuzu, Fumitaka, Ikewaki, Katsunori

“…OBJECTIVE—ATP-binding cassette transporter A1 (ABCA1) and ABCG1 are key molecules in an initial step of reverse cholesterol transport (RCT), a major…”
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Coffee Consumption Enhances High-Density Lipoprotein–Mediated Cholesterol Efflux in Macrophages by Uto-Kondo, Harumi, Ayaori, Makoto, Ogura, Masatsune, Nakaya, Kazuhiro, Ito, Mai, Suzuki, Atsushi, Takiguchi, Shun-ichi, Yakushiji, Emi, Terao, Yoshio, Ozasa, Hideki, Hisada, Tetsuya, Sasaki, Makoto, Ohsuzu, Fumitaka, Ikewaki, Katsunori

“…RATIONALE:Association of habitual coffee consumption with coronary heart disease morbidity and mortality has not been established. We hypothesized that coffee…”
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Dipeptidyl Peptidase‐4 Inhibitors Attenuate Endothelial Function as Evaluated by Flow‐Mediated Vasodilatation in Type 2 Diabetic Patients by Ayaori, Makoto, Iwakami, Naotsugu, Uto‐Kondo, Harumi, Sato, Hiroki, Sasaki, Makoto, Komatsu, Tomohiro, Iizuka, Maki, Takiguchi, Shunichi, Yakushiji, Emi, Nakaya, Kazuhiro, Yogo, Makiko, Ogura, Masatsune, Takase, Bonpei, Murakami, Takehiko, Ikewaki, Katsunori

“…Background Endothelial dysfunction is an independent predictor for cardiovascular events in patients with type 2 diabetes (T2DM). Glucagon like peptide‐1…”
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Probucol-Oxidized Products, Spiroquinone and Diphenoquinone, Promote Reverse Cholesterol Transport in Mice by Yakushiji, Emi, Ayaori, Makoto, Nishida, Takafumi, Shiotani, Kazusa, Takiguchi, Shunichi, Nakaya, Kazuhiro, Uto-Kondo, Harumi, Ogura, Masatsune, Sasaki, Makoto, Yogo, Makiko, Komatsu, Tomohiro, Lu, Rui, Yokoyama, Shinji, Ikewaki, Katsunori

“…OBJECTIVE—Oxidized products of probucol, spiroquinone and diphenoquinone, were shown to increase cell cholesterol release and plasma high-density lipoprotein…”
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Massive Hemoptysis due to Right Inferior Phrenic Artery-to-Right Pulmonary Artery Fistula in the Right Middle Lobe of the Lung by Yakushiji, Emi, Ota, Shinichiro, Komatsu, Tomohiro, Ayaori, Makoto, Ikewaki, Katsunori

“…Massive hemoptysis is a medical emergency and needs immediate treatment. It occurs in a wide variety of pulmonary diseases and typically originates from the…”
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Astaxanthin Enhances ATP-Binding Cassette Transporter A1/G1 Expressions and Cholesterol Efflux from Macrophages by IIZUKA, Maki, AYAORI, Makoto, UTO-KONDO, Harumi, YAKUSHIJI, Emi, TAKIGUCHI, Shunichi, NAKAYA, Kazuhiro, HISADA, Tetsuya, SASAKI, Makoto, KOMATSU, Tomohiro, YOGO, Makiko, KISHIMOTO, Yoshimi, KONDO, Kazuo, IKEWAKI, Katsunori

“…ATP-binding cassette transporters (ABC) A1 and G1 are key molecules in cholesterol efflux from macrophages, which is an initial step of reverse cholesterol…”
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Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages by Ayaori, Makoto, Yakushiji, Emi, Ogura, Masatsune, Nakaya, Kazuhiro, Hisada, Tetsuya, Uto-Kondo, Harumi, Takiguchi, Shunichi, Terao, Yoshio, Sasaki, Makoto, Komatsu, Tomohiro, Iizuka, Maki, Yogo, Makiko, Uehara, Yoshinari, Kagechika, Hiroyuki, Nakanishi, Tsuyoshi, Ikewaki, Katsunori

“…ABC transporter G1 (ABCG1) plays a pivotal role in HDL-mediated cholesterol efflux and atherogenesis. We investigated whether, and how, retinoic acid receptors…”
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Telmisartan Enhances Cholesterol Efflux from THP-1 Macrophages by Activating PPARγ by Nakaya, Kazuhiro, Ayaori, Makoto, Hisada, Tetsuya, Sawada, Shojiro, Tanaka, Nobukiyo, Iwamoto, Noriyuki, Ogura, Masatsune, Yakushiji, Emi, Kusuhara, Masatoshi, Nakamura, Haruo, Ohsuzu, Fumitaka

“…Aim: The ATP binding cassette transporters A1 and G1 (ABCA1/G1) and scavenger receptor class B type I (SR-BI) are key molecules in cholesterol efflux and…”
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Citrulline increases cholesterol efflux from macrophages in vitro and ex vivo via ATP-binding cassette transporters by Uto-Kondo, Harumi, Ayaori, Makoto, Nakaya, Kazuhiro, Takiguchi, Shunichi, Yakushiji, Emi, Ogura, Masatsune, Terao, Yoshio, Ozasa, Hideki, Sasaki, Makoto, Komatsu, Tomohiro, Sotherden, Grace Megumi, Hosoai, Tamaki, Sakurada, Masami, Ikewaki, Katsunori

“…Reverse cholesterol transport (RCT) is a mechanism critical to the anti-atherogenic property of HDL. Although citrulline contributes to the amelioration of…”
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Effect of Sulfonylurea Agents on Reverse Cholesterol Transport in Vitro and Vivo by Terao, Yoshio, Ayaori, Makoto, Ogura, Masatsune, Yakushiji, Emi, Uto-Kondo, Harumi, Hisada, Tetsuya, Ozasa, Hideki, Takiguchi, Shunichi, Nakaya, Kazuhiro, Sasaki, Makoto, Komatsu, Tomohiro, Iizuka, Maki, Horii, Shunpei, Mochizuki, Seibu, Yoshimura, Michihiro, Ikewaki, Katsunori

“…Aim: Reverse cholesterol transport (RCT) is a critical mechanism for the anti-atherogenic property of HDL. The inhibitory effect of the sulfonylurea agent…”
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Hepatic Overexpression of Endothelial Lipase Lowers High-Density Lipoprotein but Maintains Reverse Cholesterol Transport in Mice: Role of Scavenger Receptor Class B Type I/ATP-Binding Cassette Transporter A1-Dependent Pathways by Takiguchi, Shunichi, Ayaori, Makoto, Yakushiji, Emi, Nishida, Takafumi, Nakaya, Kazuhiro, Sasaki, Makoto, Iizuka, Maki, Uto-Kondo, Harumi, Terao, Yoshio, Yogo, Makiko, Komatsu, Tomohiro, Ogura, Masatsune, Ikewaki, Katsunori

“…OBJECTIVE—Reverse cholesterol transport (RCT) is a major mechanism by which HDL (high-density lipoprotein) protects against atherosclerosis. Endothelial lipase…”
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TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis by Hsieh, Joanne, Koseki, Masahiro, Molusky, Matthew M., Yakushiji, Emi, Ichi, Ikuyo, Westerterp, Marit, Iqbal, Jahangir, Chan, Robin B., Abramowicz, Sandra, Tascau, Liana, Takiguchi, Shunichi, Yamashita, Shizuya, Welch, Carrie L., Di Paolo, Gilbert, Hussain, M. Mahmood, Lefkowitch, Jay H., Rader, Daniel J., Tall, Alan R.

“…In mice, deficiency in the high-density lipoprotein gene T39 stabilizes liver X receptor (LXR), reducing both atherosclerosis and steatohepatitis, suggesting…”
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Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: Findings from in vitro and ex vivo studies by Ozasa, Hideki, Ayaori, Makoto, Iizuka, Maki, Terao, Yoshio, Uto-Kondo, Harumi, Yakushiji, Emi, Takiguchi, Shunichi, Nakaya, Kazuhiro, Hisada, Tetsuya, Uehara, Yoshinari, Ogura, Masatsune, Sasaki, Makoto, Komatsu, Tomohiro, Horii, Shunpei, Mochizuki, Seibu, Yoshimura, Michihiro, Ikewaki, Katsunori

“…Abstract Objective Pioglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, reportedly reduces cardiovascular events in diabetic patients…”
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Atorvastatin Reduces Circulating S100A12 Levels in Patients with Carotid Atherosclerotic Plaques - A Link with Plaque Inflammation by Komatsu, Tomohiro, Ayaori, Makoto, Uto-Kondo, Harumi, Hayashi, Katsumi, Tamura, Katsumi, Sato, Hiroki, Sasaki, Makoto, Nishida, Takafumi, Takiguchi, Shunichi, Yakushiji, Emi, Nakaya, Kazuhiro, Ikewaki, Katsunori

“…Aims: Inflammation is involved in various processes of atherosclerosis development. Serum C-reactive protein (CRP) levels, a predictor for cardiovascular risk,…”
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Hepatic Overexpression of Idol Increases Circulating Protein Convertase Subtilisin/Kexin Type 9 in Mice and Hamsters via Dual Mechanisms: Sterol Regulatory Element–Binding Protein 2 and Low-Density Lipoprotein Receptor–Dependent Pathways by Sasaki, Makoto, Terao, Yoshio, Ayaori, Makoto, Uto-Kondo, Harumi, Iizuka, Maki, Yogo, Makiko, Hagisawa, Kosuke, Takiguchi, Shunichi, Yakushiji, Emi, Nakaya, Kazuhiro, Ogura, Masatsune, Komatsu, Tomohiro, Ikewaki, Katsunori

“…OBJECTIVE—Low-density lipoprotein receptor (LDLR) is degraded by inducible degrader of LDLR (Idol) and protein convertase subtilisin/kexin type 9 (PCSK9),…”
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Ezetimibe enhances macrophage reverse cholesterol transport in hamsters: Contribution of hepato–biliary pathway by Uto-Kondo, Harumi, Ayaori, Makoto, Sotherden, Grace Megumi, Nakaya, Kazuhiro, Sasaki, Makoto, Yogo, Makiko, Komatsu, Tomohiro, Takiguchi, Shunichi, Yakushiji, Emi, Ogura, Masatsune, Nishida, Takafumi, Endo, Yasuhiro, Ikewaki, Katsunori

“…Reverse cholesterol transport (RCT) is pivotal in the return of excess cholesterol from peripheral tissues to the liver for excretion in bile and eventually…”
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Statin inhibits hypoxia-induced endothelin-1 via accelerated degradation of HIF-1α in vascular smooth muscle cells by Hisada, Tetsuya, Ayaori, Makoto, Ohrui, Nobuhiro, Nakashima, Hiroshi, Nakaya, Kazuhiro, Uto-Kondo, Harumi, Yakushiji, Emi, Takiguchi, Shunichi, Terao, Yoshio, Miyamoto, Yoshinori, Adachi, Takeshi, Nakamura, Haruo, Ohsuzu, Fumitaka, Ikewaki, Katsunori, Sakurai, Yutaka

“…Endothelin-1 (ET-1) contributes to the pathogenesis of cardiovascular diseases with multiple properties such as vasoconstriction. Human ET-1 gene expression is…”
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The role of TTC39B in atherosclerosis and non-alcoholic steatohepatitis by Koseki, Masahiro, Hsieh, Joanne, Molusky, Matthew, Yakushiji, Emi, Westerterp, Marit, Ichi, Ikuyo, Abramowicz, Sandra, Tascau, Liana, Welch, Carrie, Takiguchi, Shunichi, Iqbal, Jahangir, Sakata, Yasushi, Yamashita, Shizuya, Hussain, Mahmood, Rader, Daniel, Tall, Alan

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Abstract 20416: Ttc39b Deficiency Has a Beneficial Role on Cholesterol and Triglyceride Absorption in Enterocytes by Koseki, Masahiro, Hsieh, Joanne, Yakushiji, Emi, Welch, Carrie, Iqbal, Jahangir, Hussain, Mahmood M, Tall, Alan R, Sakata, Yasushi, Yamashita, Shizuya

“…Abstract only Background: TTC39B , encoding tetratricopeptide repeat domain 39B, was identified in genome wide association studies (GWAS) as a novel gene…”
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