Search Results - "YAKKUNDI, Anita"

Challenges in the Practice of Sexual Medicine in the Time of COVID-19 in the United Kingdom by Jacob, Louis, Smith, Lee, Butler, Laurie, Barnett, Yvonne, Grabovac, Igor, McDermott, Daragh, Armstrong, Nicola, Yakkundi, Anita, Tully, Mark A.

“…On 23rd March 2020, the UK government released self-isolation/social distancing guidance to reduce the risk of transmission of SARS-CoV-2. The influence such…”
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Alcohol use and mental health during COVID-19 lockdown: A cross-sectional study in a sample of UK adults by Jacob, Louis, Smith, Lee, Armstrong, Nicola C., Yakkundi, Anita, Barnett, Yvonne, Butler, Laurie, McDermott, Daragh T., Koyanagi, Ai, Shin, Jae Il, Meyer, Jacob, Firth, Joseph, Remes, Olivia, López-Sánchez, Guillermo F., Tully, Mark A.

“…•More than one in six UK adults increased their alcohol consumption during lockdown.•Increased alcohol consumption was associated with poor overall mental…”
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The relationship between physical activity and mental health in a sample of the UK public: A cross-sectional study during the implementation of COVID-19 social distancing measures by Jacob, Louis, Tully, Mark A., Barnett, Yvonne, Lopez-Sanchez, Guillermo F., Butler, Laurie, Schuch, Felipe, López-Bueno, Rubén, McDermott, Daragh, Firth, Joseph, Grabovac, Igor, Yakkundi, Anita, Armstrong, Nicola, Young, Timothy, Smith, Lee

“…The aim of the present study was to investigate the cross-sectional association between physical activity levels with depressive symptoms, anxiety symptoms,…”
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The association between screen time and mental health during COVID-19: A cross sectional study by Smith, Lee, Jacob, Louis, Trott, Mike, Yakkundi, Anita, Butler, Laurie, Barnett, Yvonne, Armstrong, Nicola C, McDermott, Daragh, Schuch, Felipe, Meyer, Jacob, López-Bueno, Rubén, Sánchez, Guillermo F. López, Bradley, Declan, Tully, Mark A

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FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer by Annett, Stephanie, Moore, Gillian, Short, Amy, Marshall, Andrea, McCrudden, Cian, Yakkundi, Anita, Das, Sudipto, McCluggage, W. Glenn, Nelson, Laura, Harley, Ian, Moustafa, Nermeen, Kennedy, Catherine J., deFazio, Anna, Brand, Alison, Sharma, Raghwa, Brennan, Donal, O’Toole, Sharon, O’Leary, John, Bates, Mark, O’Riain, Ciarán, O’Connor, Darran, Furlong, Fiona, McCarthy, Helen, Kissenpfennig, Adrien, McClements, Lana, Robson, Tracy

“…Background ALM201 is a therapeutic peptide derived from FKBPL that has previously undergone preclinical and clinical development for oncology indications and…”
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FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4 by McClements, Lana, Annett, Stephanie, Yakkundi, Anita, O'Rourke, Martin, Valentine, Andrea, Moustafa, Nermeen, Alqudah, Abdelrahim, Simões, Bruno M, Furlong, Fiona, Short, Amy, McIntosh, Stuart A, McCarthy, Helen O, Clarke, Robert B, Robson, Tracy

“…Optimising breast cancer treatment remains a challenge. Resistance to therapy is a major problem in both ER- and ER+ breast cancer. Tumour recurrence after…”
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Prevalence and correlates of physical activity in a sample of UK adults observing social distancing during the COVID-19 pandemic by Smith, Lee, Jacob, Louis, Butler, Laurie, Schuch, Felipe, Barnett, Yvonne, Grabovac, Igor, Veronese, Nicola, Caperchione, Cristina, Lopez-Sanchez, Guillermo F, Meyer, Jacob, Abufaraj, Mohammad, Yakkundi, Anita, Armstrong, Nicola, Tully, Mark A

“…ObjectiveTo investigate the levels and correlates of physical activity during COVID-19 social distancing in a sample of the UK public.MethodsThis paper…”
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Heart rate variability biofeedback to reduce anxiety in autism spectrum disorder - a mini review by Coulter, Helen L, Donnelly, Mark P, Yakkundi, Anita, McAneney, Helen, Barr, Owen G, Kernohan, W George

“…There is a reported high prevalence of anxiety in people with autism spectrum disorder. This mini review appraises existing research investigating heart rate…”
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FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis by Yakkundi, Anita, Bennett, Rachel, Hernández-Negrete, Ivette, Delalande, Jean-Marie, Hanna, Mary, Lyubomska, Oksana, Arthur, Kenneth, Short, Amy, McKeen, Hayley, Nelson, Laura, McCrudden, Cian M, McNally, Ross, McClements, Lana, McCarthy, Helen O, Burns, Alan J, Bicknell, Roy, Kissenpfennig, Adrien, Robson, Tracy

“…The antitumor effects of FK506-binding protein like (FKBPL) and its extracellular role in angiogenesis are well characterized; however, its role in…”
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The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases by McClements, Lana, Annett, Stephanie, Yakkundi, Anita, Robson, Tracy

“…Peptidyl prolyl isomerases (PPIases) are proteins belonging to the immunophilin family and are characterised by their cis-trans isomerization activity at the…”
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The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway by Yakkundi, Anita, McCallum, Lynn, O'Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D, McClements, Lana, Elliott, Christopher, McCarthy, Helen O, Hirst, David G, Robson, Tracy

“…FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in…”
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People with Disabilities Leading the Design of Serious Games and Virtual Worlds by Politis, Yurgos, Robb, Nigel, Yakkundi, Anita, Dillenburger, Karola, Herbertson, Nicola, Charlesworth, Beth, Goodman, Lizbeth

“…Games and virtual worlds have many potential benefits for people with intellectual disabilities (ID) and autism spectrum disorder (ASD), in terms of training,…”
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Correlates of symptoms of anxiety and depression and mental wellbeing associated with COVID-19: a cross-sectional study of UK-based respondents by Smith, Lee, Jacob, Louis, Yakkundi, Anita, McDermott, Daragh, Armstrong, Nicola C, Barnett, Yvonne, López-Sánchez, Guillermo F., Martin, Suzanne, Butler, Laurie, Tully, Mark A

“…•932 UK participants during COVID-19 self-isolation were included.•The prevalence of poor mental health was 36.8% in the population.•Females, younger age,…”
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RALA-mediated delivery of FKBPL nucleic acid therapeutics by Bennett, Rachel, Yakkundi, Anita, McKeen, Hayley D, McClements, Lana, McKeogh, Thomas J, McCrudden, Cian M, Arthur, Kenneth, Robson, Tracy, McCarthy, Helen O

“…RALA is a novel 30 mer bioinspired amphipathic peptide that is showing promise for gene delivery. Here, we used RALA to deliver the FK506-binding protein like…”
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Changes in dietary fat intake and associations with mental health in a UK public sample during the COVID-19 pandemic by Wilson, Jason J, McMullan, Ilona, Blackburn, Nicole E, Klempel, Natalie, Yakkundi, Anita, Armstrong, Nicola C, Brolly, Colette, Butler, Laurie T, Barnett, Yvonne, Jacob, Louis, Koyanagi, Ai, Smith, Lee, Tully, Mark A

“…ABSTRACT Background Consumption of unhealthy foods may have changed during the COVID-19 pandemic. This study explored how dietary fat intake was impacted in a…”
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User Centered Reading Intervention for Individuals with Autism and Intellectual Disability by Yakkundi, Anita, Dillenburger, Karola, Goodman, Lizbeth, Dounavi, Katerina

“…Individuals with autism and intellectual disability (ID) have complex learning needs and often have difficulty in acquiring reading comprehension skills using…”
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Targeting Treatment-Resistant Breast Cancer Stem Cells with FKBPL and Its Peptide Derivative, AD-01, via the CD44 Pathway by MCCLEMENTS, Lana, YAKKUNDI, Anita, MCINTOSH, Stuart, MCCARTHY, Helen O, O'NEILL, Eric, CLARKE, Robert B, ROBSON, Tracy, PAPASPYROPOULOS, Angelos, HARRISON, Hannah, ABLETT, Matthew P, JITHESH, Puthen V, MCKEEN, Hayley D, BENNETT, Rachel, DONLEY, Christopher, KISSENPFENNIG, Adrien

“…FK506-binding protein like (FKBPL) and its peptide derivative, AD-01, have already shown tumor growth inhibition and CD44-dependent antiangiogenic activity…”
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Changes in Health-Related Behaviours and Mental Health in a UK Public Sample during the First Set of COVID-19 Public Health Restrictions by Wilson, Jason J, Smith, Lee, Yakkundi, Anita, Jacob, Louis, Martin, Suzanne, Grabovac, Igor, McDermott, Daragh T, López-Bueno, Rubén, Barnett, Yvonne, Butler, Laurie T, Schuch, Felipe B, Armstrong, Nicola C, Tully, Mark A

“…Public health restrictions, in response to the COVID-19 pandemic, have had potentially wide-ranging, unintended effects on health-related behaviours such as…”
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Abstract LB-054: FKBPL as a novel therapeutic target and prognostic biomarker in high grade serous ovarian cancer by Annett, Stephanie, Moore, Gillian, Short, Amy, Moustafa, Neermeen, Das, Sudipto, O'Connor, Darran, McCrudden, Cian, Kissenpfenning, Adrien, Nelson, Laura, Harley, Ian, Arthur, Ken, Yakkundi, Anita, McCluggage, Glen, Marshall, Andrea, Furlong, Fiona, McCarthy, Helen O., Cotton, Graham, Harrison, Timothy, McClements, Lana, Robson, Tracy

“…Abstract FKBPL is a secreted protein with well-established anti-angiogenic and anti-cancer stem cell activity. A novel therapeutic peptide, ALM201, derived…”
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FKBPL and Peptide Derivatives: Novel Biological Agents that Inhibit Angiogenesis by a CD44-Dependent Mechanism by VALENTINE, Andrea, O'ROURKE, Martin, MCKEEN, Hayley, WAUGH, David J. J, ROBERTS, Jennifer, MCGREGOR, Joanne, COTTON, Graham, JAMES, Lain, HARRISON, Timothy, HIRST, David G, ROBSON, Tracy, YAKKUNDI, Anita, WORTHINGTON, Jenny, HOOKHAM, Michelle, BICKNELL, Roy, MCCARTHY, Helen O, MCCLELLAND, Keeva, MCCALLUM, Lynn, DYER, Hayder

“…Antiangiogenic therapies can be an important adjunct to the management of many malignancies. Here we investigated a novel protein, FKBPL, and peptide…”
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