Search Results - "Xynos, Ioannis"

Vismodegib in patients with advanced basal cell carcinoma (STEVIE): a pre-planned interim analysis of an international, open-label trial by Basset-Seguin, Nicole, Prof, Hauschild, Axel, Prof, Grob, Jean-Jacques, Prof, Kunstfeld, Rainer, Prof, Dréno, Brigitte, Prof, Mortier, Laurent, Prof, Ascierto, Paolo A, Prof, Licitra, Lisa, MD, Dutriaux, Caroline, MD, Thomas, Luc, Prof, Jouary, Thomas, MD, Meyer, Nicolas, MD, Guillot, Bernard, Prof, Dummer, Reinhard, Prof, Fife, Kate, MD, Ernst, D Scott, Prof, Williams, Sarah, MSc, Fittipaldo, Alberto, MD, Xynos, Ioannis, MD, Hansson, Johan, Prof

“…Summary Background The Hedgehog pathway inhibitor vismodegib has shown clinical benefit in patients with advanced basal cell carcinoma and is approved for…”
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Nivolumab (NIVO) plus ipilimumab (IPI) or NIVO plus chemotherapy (chemo) versus chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): First results of the CheckMate 648 study by Chau, Ian, Doki, Yuichiro, Ajani, Jaffer A., Xu, Jianming, Wyrwicz, Lucjan, Motoyama, Satoru, Ogata, Takashi, Kawakami, Hisato, Hsu, Chih-Hung, Adenis, Antoine, El Hajbi, Farid, Di Bartolomeo, Maria, Braghiroli, Maria Ignez Freitas Melro, Holtved, Eva, Xynos, Ioannis, Liu, Xuan, Lei, Ming, Kondo, Kaoru, Kato, Ken, Kitagawa, Yuko

“…Abstract only LBA4001 Background: NIVO demonstrated superior overall survival (OS) vs chemo in previously treated patients (pts) with ESCC (ATTRACTION-3). We…”
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Predictors of Survival in Stage IV Metastatic Colorectal Cancer by ZACHARAKIS, Michalis, XYNOS, Ioannis D, SYRIOS, John, ZOGRAFOS, George, PAPALAMBROS, Alexandros, TSAVARIS, Nikolas, LAZARIS, Andreas, SMARO, Tsaousi, KOSMAS, Christos, DOKOU, Anna, FELEKOURAS, Evangelos, ANTONIOU, Efstathios, POLYZOS, Aris, SARANTONIS, John

“…The aim of this study was to evaluate predictors of survival in stage IV metastatic colorectal cancer (CRC). A total of 541 patients with histologically proven…”
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Survival in patients with stage IV noncardia gastric cancer - the influence of DNA ploidy and Helicobacter pylori infection by Syrios, John, Sougioultzis, Stavros, Xynos, Ioannis D, Kavantzas, Nikolaos, Kosmas, Christos, Agrogiannis, George, Griniatsos, John, Karavokyros, Ioannis, Pikoulis, Emmanouil, Patsouris, Efstratios S, Tsavaris, Nikolas

“…Palliative surgery followed by postoperative chemotherapy is a challenging approach in the treatment of stage IV gastric cancer yet patients must be carefully…”
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Leishmaniasis, autoimmune rheumatic disease, and anti-tumor necrosis factor therapy, Europe by Xynos, Ioannis D, Tektonidou, Maria G, Pikazis, Dimitrios, Sipsas, Nikolaos V

“…We report 2 cases of leishmaniasis in patients with autoimmune rheumatic diseases in Greece. To assess trends in leishmaniasis reporting in this patient…”
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Pituitary Insufficiency after Infectious Meningitis: A Prospective Study by Tsiakalos, Aristotelis, Xynos, Ioannis D., Sipsas, Nikolaos V., Kaltsas, Gregory

“…Context: Data from previous retrospective studies and case reports have suggested that infectious diseases of the central nervous system could cause pituitary…”
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Modulation of peripheral immune responses by paclitaxel–ifosfamide–cisplatin chemotherapy in advanced non-small-cell lung cancer by Koufos, Nikolaos, Michailidou, Despina, Xynos, Ioannis D., Tomos, Periclis, Athanasiadou, Kalliopi, Kosmas, Christos, Tsavaris, Nikolaos

“…Purpose The aim of this study was to assess systemic immunological responses in non-small-cell lung cancer (NSCLC) patients with stage III/IV disease during…”
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Prior exposure to chemotherapy: a marker of sensitivity and selection for antiangiogenic therapy in breast cancer? by Xynos, Ioannis D, Tanna, Nikhil, Patten, Darren K, Palmieri, Carlo

“…The identification of patients who are more likely to derive benefit from antiangiogenic therapy is a key to refine patient selection and so maximize clinical…”
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Chemotherapy ± cetuximab modulates peripheral immune responses in metastatic colorectal cancer by Xynos, Ioannis D, Karadima, Maria L, Voutsas, Ioannis F, Amptoulach, Sousana, Skopelitis, Elias, Kosmas, Christos, Gritzapis, Angelos D, Tsavaris, Nikolas

“…To identify changes in peripheral immune responses in patients with metastatic colorectal cancer (mCRC) treated with irinotecan/5-fluorouracil/leucovorin (IFL)…”
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Pancreatic adenocarcinoma-associated polymyositis treated with corticosteroids along with cancer specific treatment: case report by Syrios, John, Kechagias, Georgios, Xynos, Ioannis D, Gamaletsou, Maria N, Papageorgiou, Aristea, Agrogiannis, George, Tsavaris, Nicolas

“…Adenocarcinoma of the pancreas only rarely is associated with inflammatory myopathy. In this setting, polymyositis may be treated with glucocorticoids in…”
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Evaluation of DNA ploidy in relation with established prognostic factors in patients with locally advanced (unresectable) or metastatic pancreatic adenocarcinoma: a retrospective analysis by Tsavaris, Nikolas, Kavantzas, Nicolaos, Tsigritis, Kostantinos, Xynos, Ioannis D, Papadoniou, Nikitas, Lazaris, Andreas, Kosmas, Christos, Agrogiannis, George, Dokou, Anna, Felekouras, Evangelos, Antoniou, Efstathios, Polyzos, Aris, Sarantonis, John, Tsipras, Heracles, Karatzas, Gavrilos, Papalambros, Alexandros, Patsouris, Efstratios S

“…Most patients with ductal pancreatic adenocarcinoma are diagnosed with locally advanced (unresectable) or metastatic disease. The aim of this study was to…”
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Ionic Products of Bioactive Glass Dissolution Increase Proliferation of Human Osteoblasts and Induce Insulin-like Growth Factor II mRNA Expression and Protein Synthesis by Xynos, Ioannis D., Edgar, Alasdair J., Buttery, Lee D.K., Hench, Larry L., Polak, Julia M.

“…Bioglass 45S5 is an osteoproductive material, which resorbs by releasing its constitutive ions into solution. Treatment with the ionic products of Bioglass…”
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Distinct patterns of angiogenic factor expression as a predictive factor of response to chemotherapy in stage IIIA non-small-cell lung cancer patients by Koufos, Nikolaos, Syrios, John, Michailidou, Despina, Xynos, Ioannis D, Lazaris, Andreas, Kavantzas, Nicolaos, Tomos, Periclis, Kakaris, Stamatis, Kosmas, Christos, Tsavaris, Nikolas

“…The expression of various angiogenic factors was assessed in tumour samples of patients with stage III non-small-cell lung cancer (NSCLC) and further evaluated…”
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DNA ploidy: a prognostic factor of response to chemotherapy and survival in metastatic gastric adenocarcinoma by Syrios, John, Kechagias, Georgios, Agrogiannis, George, Xynos, Ioannis D, Kavantzas, Nikolaos, Lazaris, Andreas C, Amptoulach, Suzanna, Mourati, Aikaterini, Sougioultzis, Stavros, Patsouris, Efstratios S, Tsavaris, Nikolas

“…Metastatic gastric adenocarcinoma confers a dismal prognosis. Several prognostic factors are needed to distinguish patients that will benefit from…”
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Hypercalcemia in a patient with cholangiocarcinoma: a case report by Xynos, Ioannis D, Sougioultzis, Stavros, Zilos, Athanasios, Evangelou, Konstantinos, Hatzis, Gregorios S

“…Humoral hypercalcemia of malignancy is rarely associated with cholangiocarcinoma (CC). A 77-year-old man was admitted with confusion. Computer tomography…”
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Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis by Kontoangelos, Konstantinos A., Kouzoupis, Anastasios V., Ferentinos, Panagiotis P., Xynos, Ioannis D., Sipsas, Nikolaos V., Papadimitriou, George N.

“…Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a…”
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Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial by Kato, Ken, Cho, Byoung Chul, Takahashi, Masanobu, Okada, Morihito, Lin, Chen-Yuan, Chin, Keisho, Kadowaki, Shigenori, Ahn, Myung-Ju, Hamamoto, Yasuo, Doki, Yuichiro, Yen, Chueh-Chuan, Kubota, Yutaro, Kim, Sung-Bae, Hsu, Chih-Hung, Holtved, Eva, Xynos, Ioannis, Kodani, Mamoru, Kitagawa, Yuko

“…Chemotherapy for patients with advanced oesophageal squamous cell carcinoma offers poor long-term survival prospects. We report the final analysis from our…”
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Factors Influencing Survival in Stage IV Colorectal Cancer: The Influence of DNA Ploidy by Xynos, Ioannis D., Kavantzas, Nicolaos, Tsaousi, Smaro, Zacharakis, Michalis, Agrogiannis, George, Kosmas, Christos, Lazaris, Andreas, Sarantonis, John, Sougioultzis, Stavros, Tzivras, Dimitrios, Polyzos, Aris, Patsouris, Efstratios S., Tsavaris, Nikolas

“…Objective. To evaluate the prognostic significance of microscopically assessed DNA ploidy and other clinical and laboratory parameters in stage IV colorectal…”
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Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma by Doki, Yuichiro, Ajani, Jaffer A, Kato, Ken, Xu, Jianming, Wyrwicz, Lucjan, Motoyama, Satoru, Ogata, Takashi, Kawakami, Hisato, Hsu, Chih-Hung, Adenis, Antoine, El Hajbi, Farid, Di Bartolomeo, Maria, Braghiroli, Maria I, Holtved, Eva, Ostoich, Sandra A, Kim, Hye R, Ueno, Masaki, Mansoor, Wasat, Yang, Wen-Chi, Liu, Tianshu, Bridgewater, John, Makino, Tomoki, Xynos, Ioannis, Liu, Xuan, Lei, Ming, Kondo, Kaoru, Patel, Apurva, Gricar, Joseph, Chau, Ian, Kitagawa, Yuko

“…Previously untreated patients with advanced esophageal cancer were randomly assigned to receive chemotherapy alone, chemotherapy plus nivolumab, or nivolumab…”
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Three-Year Follow-Up and Response-Survival Relationship of Nivolumab in Previously Treated Patients with Advanced Esophageal Squamous Cell Carcinoma (ATTRACTION-3) by Okada, Morihito, Kato, Ken, Cho, Byoung Chul, Takahashi, Masanobu, Lin, Chen-Yuan, Chin, Keisho, Kadowaki, Shigenori, Ahn, Myung-Ju, Hamamoto, Yasuo, Doki, Yuichiro, Yen, Chueh-Chuan, Kubota, Yutaro, Kim, Sung-Bae, Hsu, Chih-Hung, Holtved, Eva, Xynos, Ioannis, Matsumura, Yasuhiro, Takazawa, Akira, Kitagawa, Yuko

“…Limited long-term data are available on immune checkpoint inhibitor use in patients with advanced esophageal squamous cell carcinoma (ESCC). We report 3-year…”
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