Search Results - "Xuegong Fan"

Role of the intestinal microbiome in liver fibrosis development and new treatment strategies by Zhou, Rongrong, Fan, Xuegong, Schnabl, Bernd

“…Liver cirrhosis is a major cause of morbidity and mortality worldwide. The most common chronic liver diseases in western countries are alcohol-associated liver…”
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Research progress in use of traditional Chinese medicine for treatment of spinal cord injury by Lu, Yubao, Yang, Jingjing, Wang, Xuexi, Ma, Zhanjun, Li, Sheng, Liu, Zhaoyang, Fan, Xuegong

“…[Display omitted] Spinal cord injury (SCI) is a serious central nervous system disorder caused by trauma that has gradually become a major challenge in…”
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Systematic review and meta-analysis of detecting galactomannan in bronchoalveolar lavage fluid for diagnosing invasive aspergillosis by Zou, Mingxiang, Tang, Lanhua, Zhao, Shushan, Zhao, Zijin, Chen, Luyao, Chen, Peng, Huang, Zebing, Li, Jun, Chen, Lizhang, Fan, Xuegong

“…Bronchoalveolar lavage (BAL) galactomannan (GM) assay has been used for diagnosing invasive aspergillosis (IA). We aimed to derive a definitive estimate of the…”
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Tryptophan-sorbitol based carbon quantum dots for theranostics against hepatocellular carcinoma by Wang, Yang, Chen, Jun, Tian, Jiekang, Wang, Guanchen, Luo, Weikang, Huang, Zebing, Huang, Yan, Li, Ning, Guo, Mingming, Fan, Xuegong

“…Despite novel advances in screening, targeting and immunotherapies, early diagnosis and satisfactory treatments against hepatocellular carcinoma (HCC) remain…”
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Liver in infections: a single-cell and spatial transcriptomics perspective by Zou, Ju, Li, Jie, Zhong, Xiao, Tang, Daolin, Fan, Xuegong, Chen, Ruochan

“…The liver is an immune organ that plays a vital role in the detection, capture, and clearance of pathogens and foreign antigens that invade the human body…”
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PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells by Yin, Linglong, Liu, Youhong, Peng, Yuchong, Peng, Yongbo, Yu, Xiaohui, Gao, Yingxue, Yuan, Bowen, Zhu, Qianling, Cao, Tuoyu, He, Leye, Gong, Zhicheng, Sun, Lunquan, Fan, Xuegong, Li, Xiong

“…The poly ADP ribose polymerase (PARP) inhibitor olaparib has been approved for treating prostate cancer (PCa) with BRCA mutations, and veliparib, another PARP…”
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VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway by Pu, Zhangya, Duda, Dan G, Zhu, Yuanyuan, Pei, Siya, Wang, Xiaofang, Huang, Yan, Yi, Panpan, Huang, Zebing, Peng, Fang, Hu, Xingwang, Fan, Xuegong

“…Hepatocellular carcinoma (HCC) is the most common pathological type of liver cancer. Valosin-containing protein (VCP) is a member of the AAA-ATPase family…”
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Hepatic stellate cell‐released CXCL1 aggravates HCC malignant behaviors through the MIR4435‐2HG/miR‐506‐3p/TGFB1 axis by Li, Shaling, Hu, Xingwang, Yu, Songman, Yi, Panpan, Chen, Ruochan, Huang, Zebing, Huang, Yan, Huang, Yun, Zhou, Rongrong, Fan, Xuegong

“…Hepatic stellate cell (HSC) activation is a critical event in the development of hepatic fibrosis and hepatocellular carcinoma (HCC). By the release of soluble…”
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The FOXM1–ABCC5 axis contributes to paclitaxel resistance in nasopharyngeal carcinoma cells by Hou, Youxiang, Zhu, Qianling, Li, Zheng, Peng, Yongbo, Yu, Xiaohui, Yuan, Bowen, Liu, Yijun, Liu, Youhong, Yin, Linglong, Peng, Yuchong, Jiang, Zhenghua, Li, Jinping, Xie, Bowen, Duan, Yumei, Tan, Guolin, Gulina, Kurban, Gong, Zhicheng, Sun, Lunquan, Fan, Xuegong, Li, Xiong

“…Paclitaxel is clinically used as a first-line chemotherapeutic regimen for several cancer types, including head and neck cancers. However, acquired drug…”
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Sphingosine‐1‐phosphate receptor 1 mediates elevated IL‐6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease by Zhao, Shushan, Adebiyi, Morayo G., Zhang, Yujin, Couturier, Jacob P., Fan, Xuegong, Zhang, Hongqi, Kellems, Rodney E., Lewis, Dorothy E., Xia, Yang

“…Sphingosine‐1‐phosphate (S1P) is a biolipid involved in chronic inflammation in several inflammatory disorders. Recent studies revealed that elevated S1P…”
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CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression by Liu, Yi, Chen, Simin, Peng, Gang, Liao, Yiwei, Fan, Xuegong, Zhang, Zuping, Shen, Chenfu

“…Abstract Background An increasing number of studies have shown that circular RNAs (circRNAs) play important roles in the regulation of tumor progression…”
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Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response by Li, Jia, He, Jiang, Fu, Yongming, Hu, Xingwang, Sun, Lun-Quan, Huang, Yan, Fan, Xuegong

“…Chronic Hepatitis B virus (HBV) infection is a major risk of hepatocellular carcinoma (HCC) worldwide. Hepatitis B virus X protein (HBx) is encoded by one of…”
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Safety and Efficacy of Tenofovir Alafenamide Fumarate in Early-Middle Pregnancy for Mothers With Chronic Hepatitis B by Chen, Ruochan, Zou, Ju, Long, Liyuan, Huang, Haiyue, Zhang, Min, Fan, Xuegong, Huang, Yan

“…Tenofovir alafenamide fumarate has been used in late pregnancy; however, no data exist regarding its safety and effectiveness in early and middle pregnancy for…”
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A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation by Li, Wei, Zhu, Shu, Li, Jianhua, Huang, Yan, Zhou, Rongrong, Fan, Xuegong, Yang, Huan, Gong, Xing, Eissa, N Tony, Jahnen-Dechent, Willi, Wang, Ping, Tracey, Kevin J, Sama, Andrew E, Wang, Haichao

“…A liver-derived protein, fetuin-A, was first purified from calf fetal serum in 1944, but its potential role in lethal systemic inflammation was previously…”
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STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment by Pu, Zhangya, Liu, Jinghua, Liu, Zelong, Peng, Fang, Zhu, Yuanyuan, Wang, Xiaofang, He, Jiayan, Yi, Panpan, Hu, Xingwang, Fan, Xuegong, Chen, Jiang

“…Abstract Background Hepatocellular carcinoma (HCC) is one of the most malignant solid tumors worldwide. Recent evidence shows that the stimulator of interferon…”
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A tightly regulated IL-22 response maintains immune functions and homeostasis in systemic viral infection by Yi, Panpan, Liang, Yuejin, Yuan, Denley Ming Kee, Jie, Zuliang, Kwota, Zakari, Chen, Yan, Cong, Yingzi, Fan, Xuegong, Sun, Jiaren

“…Interleukin-22 (IL-22) plays an important role in host immunity and tissue homeostasis in infectious and inflammatory diseases. However, the function and…”
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Correction to: PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/. BRCA1 DNA damage repair complex in prostate cancer cells by Yin, Linglong, Liu, Youhong, Peng, Yuchong, Peng, Yongbo, Yu, Xiaohui, Gao, Yingxue, Yuan, Bowen, Zhu, Qianling, Cao, Tuoyu, He, Leye, Gong, Zhicheng, Sun, Lunquan, Fan, Xuegong, Li, Xiong

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Correction: Systematic Review and Meta-Analysis of Detecting Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosing Invasive Aspergillosis by Zou, Mingxiang, Tang, Lanhua, Zhao, Shushan, Zhao, Zijin, Chen, Luyao, Chen, Peng, Huang, Zebing, Li, Jun, Chen, Lizhang, Fan, Xuegong

“…[This corrects the article DOI: 10.1371/journal.pone.0043347.]…”
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Oral Phosphatidylcholine Improves Intestinal Barrier Function in Drug-Induced Liver Injury in Rats by Pan, Hongying, Yang, Danhong, Dai, Yining, Zhang, Jiajie, Zhou, Pengcheng, Huang, Haijun, Chen, Meijuan, Fan, Xue-Gong

“…Objective. Phosphatidylcholine (PC) is the major surface-active phospholipid and creates a hydrophobic nature to the surface. It has been reported to reverse…”
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Dynamic Alterations of the Gut Microbial Pyrimidine and Purine Metabolism in the Development of Liver Cirrhosis by Xiong, Yinghui, Wu, Li, Shao, Li, Wang, Yang, Huang, Zebing, Huang, Xun, Li, Chunhui, Wu, Anhua, Liu, Zhenguo, Fan, Xuegong, Zhou, Pengcheng

“…Liver cirrhosis is the common end-stage of liver disease which lacks effective treatment, thus studies to determine prevention targets are an urgent need. The…”
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