Search Results - "Xue, Yingzi"

Regulation of the Germinal Center Response by MicroRNA-155 by Thai, To-Ha, Calado, Dinis Pedro, Casola, Stefano, Ansel, K. Mark, Xiao, Changchun, Xue, Yingzi, Murphy, Andrew, Frendewey, David, Valenzuela, David, Kutok, Jeffery L, Schmidt-Supprian, Marc, Rajewsky, Nikolaus, Yancopoulos, George, Rao, Anjana, Rajewsky, Klaus

“…MicroRNAs are small RNA species involved in biological control at multiple levels. Using genetic deletion and transgenic approaches, we show that the…”
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Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor by Anderson, Keith D, Pan, Li, Yang, Xiao-man, Hughes, Virginia C, Walls, Johnathon R, Dominguez, Melissa G, Simmons, Mary V, Burfeind, Patricia, Xue, Yingzi, Wei, Yi, Macdonald, Lynn E, Thurston, Gavin, Daly, Christopher, Lin, Hsin Chieh, Economides, Aris N, Valenzuela, David M, Murphy, Andrew J, Yancopoulos, George D, Gale, Nicholas W

“…The vasculature of the CNS is structurally and functionally distinct from that of other organ systems and is particularly prone to developmental abnormalities…”
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High-throughput engineering of the mouse genome coupled with high-resolution expression analysis by Yancopoulos, George D, Valenzuela, David M, Murphy, Andrew J, Frendewey, David, Gale, Nicholas W, Economides, Aris N, Auerbach, Wojtek, Poueymirou, William T, Adams, Niels C, Rojas, Jose, Yasenchak, Jason, Chernomorsky, Rostislav, Boucher, Marylene, Elsasser, Andrea L, Esau, Lakeisha, Zheng, Jenny, Griffiths, Jennifer A, Wang, Xiaorong, Su, Hong, Xue, Yingzi, Dominguez, Melissa G, Noguera, Irene, Torres, Richard, Macdonald, Lynn E, Stewart, A Francis, DeChiara, Thomas M

“…One of the most effective approaches for determining gene function involves engineering mice with mutations or deletions in endogenous genes of interest…”
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A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development by Hadland, Brandon K., Huppert, Stacey S., Kanungo, Jyotshnabala, Xue, Yingzi, Jiang, Rulang, Gridley, Thomas, Conlon, Ronald A., Cheng, Alec M., Kopan, Raphael, Longmore, Gregory D.

“…Notch1 is known to play a critical role in regulating fates in numerous cell types, including those of the hematopoietic lineage. Multiple defects exhibited by…”
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Notch signaling is essential for vascular morphogenesis in mice by Krebs, L T, Xue, Y, Norton, C R, Shutter, J R, Maguire, M, Sundberg, J P, Gallahan, D, Closson, V, Kitajewski, J, Callahan, R, Smith, G H, Stark, K L, Gridley, T

“…The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular signaling mechanism. To assess the…”
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Protein-tyrosine Phosphatase H1 Controls Growth Hormone Receptor Signaling and Systemic Growth by Pilecka, Iwona, Patrignani, Claudia, Pescini, Rosanna, Curchod, Marie-Laure, Perrin, Dominique, Xue, Yingzi, Yasenchak, Jason, Clark, Ann, Magnone, Maria Chiara, Zaratin, Paola, Valenzuela, David, Rommel, Christian, van Huijsduijnen, Rob Hooft

“…Several protein-tyrosine phosphatases (PTPs) have been implicated in the control of growth hormone receptor (GHR) signaling, but none have been shown to affect…”
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Genetic Analysis of the Myotubularin Family of Phosphatases in Caenorhabditis elegans by Xue, Yingzi, Fares, Hanna, Grant, Barth, Li, Zhai, Rose, Ann M., Clark, Scott G., Skolnik, Edward Y.

“…Myotubularins (MTMs) constitute a large family of lipid phosphatases that specifically dephosphorylate phosphatidylinositol (3)P. MTM1 and MTM2 are mutated in…”
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Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK) by Xue, Y, Wang, X, Li, Z, Gotoh, N, Chapman, D, Skolnik, E Y

“…We have previously shown that the Drosophila Ste20 kinase encoded by misshapen (msn) is an essential gene in Drosophila development. msn function is required…”
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C1ql1/Ctrp14 and C1ql4/Ctrp11 promote angiogenesis of endothelial cells through activation of ERK1/2 signal pathway by Liu, Fang, Tan, Anni, Yang, Renhao, Xue, Yingzi, Zhang, Ming, Chen, Lei, Xiao, Luanjuan, Yang, Xuesong, Yu, Yanhong

“…C1ql-like (C1QL)-1 and -4 proteins are encoded by homologous genes that are highly expressed in brain and adipose tissues. However, functional properties of…”
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Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation by Krebs, Luke T., Xue, Yingzi, Norton, Christine R., Sundberg, John P., Beatus, Paul, Lendahl, Urban, Joutel, Anne, Gridley, Thomas

“…The Notch signaling pathway is an evolutionarily conserved signaling mechanism and mutations in its components disrupt cell fate specification and embryonic…”
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Embryonic Lethality and Vascular Defects in Mice Lacking the Notch Ligand Jagged1 by Xue, Yingzi, Gao, Xiang, Lindsell, Claire E., Norton, Christine R., Chang, Bo, Hicks, Carol, Gendron-Maguire, Maureen, Rand, Elizabeth B., Weinmaster, Gerry, Gridley, Thomas

“…The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryonic development in mammals. Mutations in the…”
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Mutations in the Caenorhabditis elegans p-tubulin gene mec-7: effects on microtubule assembly and stability and on tubulin autoregulation by Savage, Cathy, Xue, Yingzi, Mitani, Shohei, Hall, David, Zakhary, Randa, Chalfie, Martin

“…ABSTRACT We have sequenced 45 mutations in mec-7, a β-tubulin gene required for the production of 15-protofilament microtubules in the nematode Caenorhabditis…”
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The loss-of-allele assay for ES cell screening and mouse genotyping by Frendewey, David, Chernomorsky, Rostislav, Esau, Lakeisha, Om, Jinsop, Xue, Yingzi, Murphy, Andrew J, Yancopoulos, George D, Valenzuela, David M

“…Targeting vectors used to create directed mutations in mouse embryonic stem (ES) cells consist, in their simplest form, of a gene for drug selection flanked by…”
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Lentiviral vector-mediated RNA interference of mouse epididymis-specific meClps gene lowers mouse sperm mobility by Lian, Zizhen, Cao, Zuowu, Chen, Ran, Chen, Lei, Xue, Yingzi, Qin, Junwen, Qi, Xufeng, Zhang, Chunxue, Yu, Yanhong

“…To analyze the effect of small interfering RNA (siRNA) targeting mouse epididymis-specific colipase-like (meClps) gene on mouse sperm mobility. The eukaryotic…”
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Mutations in the Caenorhabditis elegans beta-tubulin gene mec-7: effects on microtubule assembly and stability and on tubulin autoregulation by Savage, C, Xue, Y, Mitani, S, Hall, D, Zakhary, R, Chalfie, M

“…We have sequenced 45 mutations in mec-7, a beta-tubulin gene required for the production of 15-protofilament microtubules in the nematode Caenorhabditis…”
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Functional analysis of Notch signaling in mice by Xue, Yingzi

“…The Notch signaling pathway is a well conserved pathway which defines a fundamental mechanism controlling cell fate. Disruption of Notch signaling leads to a…”
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Erratum: High-throughput engineering of the mouse genome coupled with high-resolution expression analysis by Valenzuela, David M, Murphy, Andrew J, Frendewey, David, Gale, Nicholas W, Economides, Aris N, Auerbach, Wojtek, Poueymirou, William T, Adams, Niels C, Rojas, Jose, Yasenchak, Jason, Chernomorski, Rostislav, Boucher, Marylene, Elsasser, Andrea L, Esau, Lakeisha, Zheng, Jenny, Griffiths, Jennifer, Wang, Xiaorong, Su, Hong, Xue, Yingzi, Dominguez, Melissa G, Noguera, Irene, Torres, Richard, Macdonald, Lynn E, Stewart, A Francis, DeChiara, Thomas M, Yancopoulos, George D

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High-throughput engineering of the mouse genome coupled with high-resolution expression analysis by Valenzuela, David M, Murphy, Andrew J, Frendewey, David, Gale, Nicholas W, Economides, Aris N, Auerbach, Wojtek, Poueymirou, William T, Adams, Niels C, Rojas, Jose, Yasenchak, Jason, Chernomorski, Rostislav, Boucher, Marylene, Elsasser, Andrea L, Esau, Lakeisha, Zheng, Jenny, Griffiths, Jennifer, Wang, Xiaorong, Su, Hong, Xue, Yingzi, Dominguez, Melissa G, Noguera, Irene, Torres, Richard, Macdonald, Lynn E, Stewart, A Francis, DeChiara, Thomas M, Yancopoulos, George D

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mbryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1 by Xue, Yingzi, Gao, Xiang, Lindsell, Claire E, Norton, Christine R, Chang, Bo, Hicks, Carol, Gendron-Maguire, Maureen, Rand, Elizabeth B, Weinmaster, Gerry, Gridley, Thomas

“…The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryonic development in mammals. Mutations in the…”
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Embryonic lethality and vascular defects in mice lacking the Notch Ligand Jagged by YINGZI XUE, XIANG GAO, LINDSELL, C. E, NORTON, C. R, BO CHANG, HICKS, C, GENDRON-MAGUIRE, M, RAND, E. B, WEINMASTER, G, GRIDLEY, T

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