Search Results - "Xue, Emily"
-
1
Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism
Published in Science translational medicine (05-07-2017)“…Breast cancer cells disseminate through TIE2/MENA /MENA -dependent cancer cell intravasation sites, called tumor microenvironment of metastasis (TMEM), which…”
Get more information
Journal Article -
2
Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination
Published in Nature communications (15-12-2021)“…Cancer stem cells (CSCs) play an important role during metastasis, but the dynamic behavior and induction mechanisms of CSCs are not well understood. Here, we…”
Get full text
Journal Article -
3
Hematogenous Dissemination of Breast Cancer Cells From Lymph Nodes Is Mediated by Tumor MicroEnvironment of Metastasis Doorways
Published in Frontiers in oncology (26-10-2020)“…In primary breast tumors, cancer cells hematogenously disseminate through doorways in the vasculature composed of three-cell complexes (known as Tumor…”
Get full text
Journal Article -
4
Abstract 372: Macrophage contact-dependent stemness induction and progressive CSC enrichment during metastatic dissemination in breast cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: Cancer stem cells (CSCs) play an important role during metastatic progression of breast cancer. However, little is known, at the single…”
Get full text
Journal Article -
5
Abstract 972: Direct observation in living tumors shows macrophage-dependent induction and dissemination of cancer stem cells in breast cancer
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Cancer stem cells (CSCs) play an important role during metastatic progression of breast cancer. However, the in vivo properties and dynamic behavior…”
Get full text
Journal Article -
6
Abstract 3963: Neoadjuvant chemotherapy promotes prometastatic changes in the primary breast tumor microenvironment in mice and humans
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Chemotherapy induces influx of bone marrow-derived proangiogenic Tie2hi monocytes in primary tumors. Tie2hi perivascular macrophages specifically…”
Get full text
Journal Article -
7
Selection of individual VH genes occurs at the pro-B to pre-B cell transition
Published in The Journal of immunology (1950) (15-08-2011)“…B cells are subjected to selection at multiple checkpoints during their development. The selection of Ab H chains is difficult to study because of the large…”
Get full text
Journal Article -
8
Selection of individual V$_H$ genes occurs at the pro-B to pre-B cell transition
Published in The Journal of immunology (1950) (15-08-2011)“…B cells are subjected to selection at multiple checkpoints during their development. The selection of Ab H chains is difficult to study because of the large…”
Get full text
Journal Article -
9
B-Cell Tolerance Defects in the B6.Aec1/2 Mouse Model of Sjögren’s Syndrome
Published in Journal of clinical immunology (01-06-2012)“…Purpose Primary Sjögren’s syndrome (SjS) is an autoimmune disorder characterized by lymphocytic infiltration of the salivary and lacrimal glands, B-cell clonal…”
Get full text
Journal Article -
10
BEDS-Bench: Behavior of EHR-models under Distributional Shift--A Benchmark
Published 17-07-2021“…Machine learning has recently demonstrated impressive progress in predictive accuracy across a wide array of tasks. Most ML approaches focus on generalization…”
Get full text
Journal Article