Search Results - "Xu, Zihui"

Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration by Xu, Zihui, Poidevin, Mickael, Li, Xuekun, Li, Yujing, Shu, Liqi, Nelson, David L., Li, He, Hales, Chadwick M., Gearing, Marla, Wingo, Thomas S., Jin, Peng

“…Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share phenotypic and pathologic overlap. Recently, an expansion of GGGGCC repeats in the…”
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Retinal Organoid Technology: Where Are We Now? by Zhang, Zuming, Xu, Zihui, Yuan, Fa, Jin, Kangxin, Xiang, Mengqing

“…It is difficult to regenerate mammalian retinal cells once the adult retina is damaged, and current clinical approaches to retinal damages are very limited…”
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Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus by Liu, Ji, Conde, Kristie, Zhang, Peng, Lilascharoen, Varoth, Xu, Zihui, Lim, Byung Kook, Seeley, Randy J., Zhu, J. Julius, Scott, Michael M., Pang, Zhiping P.

“…Glucagon-like Peptide 1 (GLP-1)-expressing neurons in the hindbrain send robust projections to the paraventricular nucleus of the hypothalamus (PVN), which is…”
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A Bridge-Linked Phosphorus-Containing Flame Retardant for Endowing Vinyl Ester Resin with Low Fire Hazard by Xu, Zihui, Zhan, Jing, Xu, Zhirong, Mao, Liangchen, Mu, Xiaowei, Tao, Ran

“…The high flammability of vinyl ester resin (VE) significantly limits its widespread application in the fields of electronics and aerospace. A new…”
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Stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 improves diabetic retinopathy by Deng, Lin, Jia, Jun, Yao, Jun, Xu, Zihui

“…Diabetes induced a serious of complications including diabetic retinopathy. Our study aimed to investigate the role of Stromal cell-derived factor 1 (SDF-1)…”
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Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38α MAPK During Insulin Resistance by YAJUAN QI, ZIHUI XU, QINGLEI ZHU, THOMAS, Candice, KUMAR, Rajesh, HAO FENG, DOSTAL, David E, WHITE, Morris F, BAKER, Kenneth M, SHAODONG GUO

“…Cardiac failure is a major cause of death in patients with type 2 diabetes, but the molecular mechanism that links diabetes to heart failure remains unclear…”
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Totally asymmetric simple exclusion process on a dynamic lattice with local inhomogeneity by Lin, Congping, Huang, Yuesong, Xu, Zihui, Zhang, Yiwei

“…In this manuscript, we introduce a totally asymmetric simple exclusion process on a dynamic lattice with inhomogeneity to model motor-based long-range…”
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Quercetin‐3‐O‐Glucuronide Alleviates Cognitive Deficit and Toxicity in Aβ1‐42‐Induced AD‐Like Mice and SH‐SY5Y Cells by Xu, Mengdai, Huang, Hao, Mo, Xiaoxing, Zhu, Yalun, Chen, Xi, Li, Xiaoqin, Peng, Xiaobo, Xu, Zihui, Chen, Liangkai, Rong, Shuang, Yang, Wei, Liu, Shuang, Liu, Liegang

“…Scope Alzheimer's disease (AD) is characterized by amyloid‐β (Aβ) related imbalance, Tau‐hyperphosphorylation, and neuroinflammation, in which Aβ and…”
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Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci by Forrest, Marc P., Zhang, Hanwen, Moy, Winton, McGowan, Heather, Leites, Catherine, Dionisio, Leonardo E., Xu, Zihui, Shi, Jianxin, Sanders, Alan R., Greenleaf, William J., Cowan, Chad A., Pang, Zhiping P., Gejman, Pablo V., Penzes, Peter, Duan, Jubao

“…Most disease variants lie within noncoding genomic regions, making their functional interpretation challenging. Because chromatin openness strongly influences…”
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Exploration of Weld Bead Forming Rule during Double-Pulsed GMAW Process Based on Grey Relational Analysis by Yao, Ping, Zhou, Kang, Lin, Hongyan, Xu, Zihui, Yue, Songchen

“…Weld bead forming rule is very important during double-pulsed gas metal arc welding (DP-GMAW) process, and this process has more advantages than that of…”
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Association between a high triglyceride–glucose index and chronic kidney disease in adult patients with latent autoimmune diabetes by Fu, Xiuli, Xu, Zihui, Tan, Qin, Wei, Wei, Wang, Zhongjing

“…Abstract Background Insulin resistance (IR) is one of the risk factors for chronic kidney disease (CKD) and diabetes. The triglyceride–glucose (TyG) index is…”
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Metformin increases hepatic leptin receptor and decreases steatosis in mice by Tang, Xuemei, Li, Jingwen, Xiang, Wei, Cui, Ye, Xie, Bin, Wang, Xiaodong, Xu, Zihui, Gan, Lixia

“…In addition to the ascertained efficacy as antidiabetic drug, metformin is increasingly being used as weight-loss agent in obesity, and as insulin sensitizer…”
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China’s Stem Cell Research and Knowledge Levels of Medical Practitioners and Students by Luo, Deng, Xu, Zihui, Wang, Zhongjing, Ran, Wenzhuo

“…Over the last few decades, China has greatly expanded its scope of stem cell research, generating various scientific advances and medical applications…”
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miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells by Shi, Xiaoyan, Xiao, Lan, Mao, Xiaolu, He, Jinrong, Ding, Yu, Huang, Jin, Peng, Caixia, Xu, Zihui

“…Cisplatin resistance is a major cause of treatment failure in advanced ovarian cancer. The limited evidence shows the paradoxical regulation of miR-205 on…”
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Effect of synbiotic supplementation on immune parameters and gut microbiota in healthy adults: a double-blind randomized controlled trial by Li, Xiaoqin, Hu, Shan, Yin, Jiawei, Peng, Xiaobo, King, Lei, Li, Linyan, Xu, Zihui, Zhou, Li, Peng, Zhao, Ze, Xiaolei, Zhang, Xuguang, Hou, Qiangchuan, Shan, Zhilei, Liu, Liegang

“…Synbiotics are increasingly used by the general population to boost immunity. However, there is limited evidence concerning the immunomodulatory effects of…”
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DNA Adjuvant Hydrogel‐Optimized Enzymatic Cascade Reaction for Tumor Chemodynamic‐Immunotherapy by Zhao, Yan, Du, Jiangnan, Xu, Zihui, Wang, Lihua, Ma, Lan, Sun, Lele

“…Chemodynamic therapy (CDT) shows immense potential in cancer treatment as it not only directly kills tumor cells but also induces anti‐tumor immune responses…”
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Long-Term Over-Expression of Neuropeptide Y in Hypothalamic Paraventricular Nucleus Contributes to Adipose Tissue Insulin Resistance Partly via the Y5 Receptor by Long, Min, Zhou, Jiyin, Li, Dandan, Zheng, Lu, Xu, Zihui, Zhou, Shiwen

“…Intracerebroventricular injection and overexpression of Neuropeptide Y (NPY) in the paraventricular nucleus (PVN) has been shown to induce obesity and glucose…”
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Hyperglycemia and Correlated High Levels of Inflammation Have a Positive Relationship with the Severity of Coronavirus Disease 2019 by Zhang, Wen, Li, Chuanwei, Xu, Yu, He, Binfeng, Hu, Mingdong, Cao, Guoqiang, Li, Li, Wu, Shuang, Wang, Xia, Zhang, Chun, Zhao, Jianping, Xie, Jungang, Xu, Zihui, Li, Qi, Wang, Guansong

“…Objective. Coronavirus disease 2019 (COVID-19) is a considerable global public health threat. This study sought to investigate whether blood glucose (BG)…”
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Mibefradil reduces hepatic glucose output in HepG2 cells via Ca2+/calmodulin-dependent protein kinase II-dependent Akt/forkhead box O1signaling by Ying, Dai, Mengya, Shan, Peilin, Li, Lingong, Zhao, huan, Ma, Jing, Xu, Le, Zhang, Kebin, Zhang, Bin, Chen, Jun, Yan, Shaodong, Guo, Zihui, Xu

“…The effects and underlying mechanisms of mibefradil on gluconeogenesis and glycogenesis were investigated using insulin-resistant HepG2 human hepatocellular…”
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Influence of Inclination of Welding Torch on Weld Bead during Pulsed-GMAW Process by Yao, Ping, Tang, Heqing, Zhou, Kang, Lin, Hongyan, Xu, Zihui, Du, Xiongzi

“…This work is about the influence rule of inclination of welding torch on the formation and characteristics of weld bead during the pulsed-gas metal arc welding…”
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