Search Results - "Xu, Zhong‐Gao"
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The common risk factors for progression and mortality in COVID-19 patients: a meta-analysis
Published in Archives of virology (01-08-2021)“…Coronavirus disease 2019 (COVID-19), defined by the World Health Organization (WHO), has affected more than 50 million patients worldwide and caused a global…”
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Roles of Krüppel‐like factor 5 in kidney disease
Published in Journal of cellular and molecular medicine (01-03-2021)“…Transcription factor Krüppel‐like factor 5 (KLF5) is a member of the Krüppel‐like factors’ (KLFs) family. KLF5 regulates a number of cellular functions, such…”
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3
Arginase-1-dependent promotion of TH17 differentiation and disease progression by MDSCs in systemic lupus erythematosus
Published in Science translational medicine (23-03-2016)“…Expansion of myeloid-derived suppressor cells (MDSCs) has been documented in some murine models and patients with autoimmune diseases, but the exact role of…”
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Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes
Published in The FASEB journal (01-10-2007)“…Diabetic nephropathy (DN) remains a major complication in both type 1 and type 2 diabetes. Systemic administration of antitransforming growth factor-β (TGF-β)…”
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The Role of Circulating RBP4 in the Type 2 Diabetes Patients with Kidney Diseases: A Systematic Review and Meta-Analysis
Published in Disease markers (2020)“…Background. Diabetic nephropathy is a common and serious complication of diabetes mellitus (DM) and is one of the leading causes of end-stage renal disease…”
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The Intestinal Microbiota Composition in Early and Late Stages of Diabetic Kidney Disease
Published in Microbiology spectrum (17-08-2023)“…Many studies have suggested that gut microbiota dysbiosis may be one of the pathogenesis factors of diabetes mellitus (DM), while it is not clear whether it is…”
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Renal Protective Effect of Sirtuin 1
Published in Journal of diabetes research (01-01-2014)“…Silent information regulator 2 (Sir2) is a nicotinamide adenine dinucleotide- (NAD+-) dependent deacetylase. The homology of SIRT1 and Sir2 has been…”
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Effect of peritoneal dialysis versus hemodialysis on renal anemia in renal in end-stage disease patients: a meta-analysis
Published in Renal failure (01-11-2017)“…The aim of this meta-analysis was to evaluate the effect of peritoneal dialysis (PD) and hemodialysis (HD) on renal anemia (RA) in renal disease patients by a…”
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Key Role of Src Kinase in S100B-induced Activation of the Receptor for Advanced Glycation End Products in Vascular Smooth Muscle Cells
Published in The Journal of biological chemistry (12-05-2006)“…The receptor for advanced glycation end products (RAGE) and its ligands have been implicated in the activation of oxidant stress and inflammatory pathways in…”
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12-Lipoxygenase Inhibition on Microalbuminuria in Type-1 and Type-2 Diabetes Is Associated with Changes of Glomerular Angiotensin II Type 1 Receptor Related to Insulin Resistance
Published in International journal of molecular sciences (06-05-2016)“…(1) BACKGROUND: 12-lipoxygenase (12-LO) is involved in the development of diabetic nephropathy (DN). In the present study, we investigated whether 12-LO…”
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Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes
Published in American journal of physiology. Renal physiology (01-08-2008)“…We previously showed that the 12/15-lipoxygenase (12/15-LO) pathway of arachidonate acid metabolism is involved in multiple events related to diabetic…”
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Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli
Published in Nephrology, dialysis, transplantation (01-06-2009)“…Background. Angiotensin II type 1 receptor (AT1) plays an important role in the development of diabetic nephropathy (DN). However, the roles played by…”
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Role of AT-1 receptor in regulation of vascular MCP-1, IL-6, PAI-1, MAP kinase, and matrix expressions in obesity
Published in Kidney international (01-12-2005)“…Role of AT-1 receptor in regulation of vascular MCP-1, IL-6, PAI-1, MAP kinase, and matrix expressions in obesity. Metabolic syndrome has emerged as the major…”
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Products of 12/15-Lipoxygenase Upregulate the Angiotensin II Receptor
Published in Journal of the American Society of Nephrology (01-03-2008)“…Angiotensin II and its type 1 receptor (AT1R) play important roles in the pathogenesis of renal disease and diabetic nephropathy. The 12/15-lipoxygenase…”
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Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic Nephropathy
Published in Antioxidants & redox signaling (01-03-2016)“…Epigenetic mechanisms, including histone post-translational modifications and DNA methylation, are implicated in the pathogenesis of diabetic nephropathy (DN),…”
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High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells
Published in Kidney international (01-03-2003)“…High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells. Peritoneal fibrosis is a serious complication in long-term…”
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Novel interactions between TGF-β1 actions and the 12/15-Lipoxygenase pathway in mesangial cells
Published in Journal of the American Society of Nephrology (01-02-2005)Get full text
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Endothelin receptor antagonists for the treatment of diabetic nephropathy: A meta-analysis and systematic review
Published in World journal of diabetes (15-11-2020)“…Diabetic nephropathy (DN) is the main cause of chronic kidney disease and end-stage renal disease worldwide. Although available clinical trials have shown that…”
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Roles of 12-Lipoxygenase and Its Interaction with Angiotensin II on p21 and p27 Expression in Diabetic Nephropathy
Published in Nephron (2015) (01-01-2019)“…12-Lipoxygenase (12-LO) and angiotensin II (Ang II) are involved in the development of diabetic renal hypertrophy, in which cyclin-kinase inhibitors, p21 and…”
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Meta-analysis of the efficacy and safety of nucleotide/nucleoside analog monotherapy for hepatitis B virus-associated glomerulonephritis
Published in Clinical nephrology (01-01-2016)“…Antiviral monotherapy is recommended for hepatitis B virus-associated glomerulonephritis (HBV-GN) treatment. Although considered superior to interferon-α in…”
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