Search Results - "Xu, Zhiheng"
-
1
SARS-CoV-2 Viral Load in Clinical Samples from Critically Ill Patients
Published in American journal of respiratory and critical care medicine (01-06-2020)Get full text
Journal Article -
2
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation
Published in Cell (21-09-2017)“…An emerging family of innate lymphoid cells (termed ILCs) has an essential role in the initiation and regulation of inflammation. However, it is still unclear…”
Get full text
Journal Article -
3
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein
Published in Journal of neurochemistry (01-08-2012)“…J. Neurochem. (2012) 122, 650–658. Mutations in Leucine‐rich repeat kinase 2 (LRRK2) are the leading causes of genetically inherited Parkinson’s disease (PD)…”
Get full text
Journal Article -
4
Experimental study on the buffering effects of urban trees group in dike-break floods
Published in Scientific reports (10-10-2023)“…The process of dike-break flood propagation in typical urban street is highly complex. The presence of buildings and trees groups in urban street profoundly…”
Get full text
Journal Article -
5
Cytomegalovirus infection and outcome in immunocompetent patients in the intensive care unit: a systematic review and meta-analysis
Published in BMC infectious diseases (28-06-2018)“…Cytomegalovirus (CMV) infection is common in immunocompetent patients in intensive care units (ICUs). However, whether CMV infection or CMV reactivation…”
Get full text
Journal Article -
6
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly
Published in Science (American Association for the Advancement of Science) (17-11-2017)“…Zika virus (ZIKV) has evolved into a global health threat because of its unexpected causal link to microcephaly. Phylogenetic analysis reveals that…”
Get full text
Journal Article -
7
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model
Published in Immunity (Cambridge, Mass.) (21-03-2017)“…Zika virus (ZIKV) has become a public health threat due to its global transmission and link to severe congenital disorders. The host immune responses to ZIKV…”
Get full text
Journal Article -
8
Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice
Published in Nature communications (01-06-2016)“…Several genome- and proteome-wide studies have associated transcription and translation changes of CRMP2 (collapsing response mediator protein 2) with…”
Get full text
Journal Article -
9
Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance
Published in Nature communications (18-12-2014)“…Lysine-specific demethylase 1 (LSD1) is involved in gene regulation and development; however, its precise function, molecular targets and underlying mechanisms…”
Get full text
Journal Article -
10
Flat microliter membrane-based microbial fuel cell as “on-line sticker sensor” for self-supported in situ monitoring of wastewater shocks
Published in Bioresource technology (01-12-2015)“…[Display omitted] •Flat microliter MMFC was developed as “on line sticker sensor”.•Hydrophilic and microporous membrane shortened the acclimation…”
Get full text
Journal Article -
11
Targeting Hippo pathway by specific interruption of YAP‐TEAD interaction using cyclic YAP‐like peptides
Published in The FASEB journal (01-02-2015)“…ABSTRACT Hippo signaling pathway is emerging as a novel target for anticancer therapy because it plays key roles in organ size control and tumorigenesis. As…”
Get full text
Journal Article -
12
Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins
Published in Cell stem cell (07-09-2017)“…Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact…”
Get full text
Journal Article -
13
Sepsis and ARDS: The Dark Side of Histones
Published in Mediators of Inflammation (01-01-2015)“…Despite advances in management over the last several decades, sepsis and acute respiratory distress syndrome (ARDS) still remain major clinical challenges and…”
Get full text
Journal Article -
14
Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids
Published in Cell research (01-04-2019)“…The re-emergence of Zika virus (ZIKV) in the Western Hemisphere has resulted in global public health crisis since 2015. ZIKV preferentially infects and targets…”
Get full text
Journal Article -
15
Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms
Published in Scientific reports (13-02-2017)“…Heteroaryldihydropyrimidine (HAP) and sulfamoylbenzamide (SBA) are promising non-nucleos(t)ide HBV replication inhibitors. HAPs are known to promote core…”
Get full text
Journal Article -
16
Sh3rf2 Haploinsufficiency Leads to Unilateral Neuronal Development Deficits and Autistic-Like Behaviors in Mice
Published in Cell reports (Cambridge) (11-12-2018)“…Autism spectrum disorders (ASDs) include a variety of developmental brain disorders with clinical findings implicating the dysfunction of the left hemisphere…”
Get full text
Journal Article -
17
A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection
Published in Antimicrobial agents and chemotherapy (20-12-2019)“…Hepatitis B virus (HBV) is a major human pathogen, killing an estimated 887,000 people per year. Therefore, potentially curative therapies are of high…”
Get full text
Journal Article -
18
Methylation of Ribosomal Protein S10 by Protein-arginine Methyltransferase 5 Regulates Ribosome Biogenesis
Published in The Journal of biological chemistry (23-04-2010)“…Modulation of ribosomal assembly is a fine tuning mechanism for cell number and organ size control. Many ribosomal proteins undergo post-translational…”
Get full text
Journal Article -
19
Microcephaly-Associated Protein WDR62 Regulates Neurogenesis through JNK1 in the Developing Neocortex
Published in Cell reports (Cambridge) (01-01-2014)“…Mutations of WD40-repeat protein 62 (WDR62) have been identified recently to cause human MCPH (autosomal-recessive primary microcephaly), a neurodevelopmental…”
Get full text
Journal Article -
20
Neutron-irradiated effect on the thermoelectric properties of Bi2Te3-based thermoelectric leg
Published in Nuclear engineering and technology (01-08-2023)“…Thermoelectric (TE) materials working in radioisotope thermoelectric generators are irradiated by neutrons throughout its service; thus, investigating the…”
Get full text
Journal Article