Search Results - "Xu, Zhenru"
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Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy
Published in Applied microbiology and biotechnology (01-01-2020)“…Autophagy is a highly conserved catabolic process and participates in a variety of cellular biological activities. The phosphoinositide 3-kinase (PI3K)/protein…”
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2
High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignancies
Published in Journal of hematology and oncology (13-07-2020)“…High mobility group box 1 (HMGB1) is a nonhistone chromatin-associated protein that has been widely reported to play a pivotal role in the pathogenesis of…”
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3
Analysis of ceRNA networks and identification of potential drug targets for drug-resistant leukemia cell K562/ADR
Published in PeerJ (San Francisco, CA) (25-05-2021)“…Drug resistance is the main obstacle in the treatment of leukemia. As a member of the competitive endogenous RNA (ceRNA) mechanism, underlying roles of lncRNA…”
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4
The miR‐15a/16 gene cluster in human cancer: A systematic review
Published in Journal of cellular physiology (01-05-2019)“…MicroRNAs (miRNAs) are an important class of endogenous small noncoding single‐stranded RNAs that suppress the expression of their target genes through…”
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5
Mechanical and electromagnetic shielding properties of colored Si3N4 ceramics
Published in Ceramics international (01-09-2024)“…The inherent brittleness and uniform coloration of Si3N4 materials have traditionally limited their applicability. In this study, colored Si3N4 ceramics were…”
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Comprehensive study on the mechanical properties of Ti-doped Si3N4 ceramics: Experimental analysis, DFT calculations, and machine learning
Published in Ceramics international (01-05-2024)“…This study involved the synthesis of Si3N4 ceramics, focusing on adjusting TiN content and sintering temperatures to enhance mechanical properties. Utilizing…”
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7
Introduction of long non-coding RNAs to regulate autophagy-associated therapy resistance in cancer
Published in Molecular biology reports (01-11-2022)“…Autophagy is a lysosomal degradation pathway that depends on various evolutionarily conserved autophagy-related genes (ATGs). Dysregulation of autophagy plays…”
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p19INK4d inhibits proliferation and enhances imatinib efficacy through BCR-ABL signaling pathway in chronic myeloid leukemia
Published in Blood cells, molecules, & diseases (01-11-2020)“…Chronic myeloid leukemia (CML) is a kind of myeloproliferative disorder caused by a constitutively active BCR-ABL tyrosine kinase. Tyrosine kinase inhibitors…”
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9
p19 INK4d inhibits proliferation and enhances imatinib efficacy through BCR-ABL signaling pathway in chronic myeloid leukemia
Published in Blood cells, molecules, & diseases (01-11-2020)“…Chronic myeloid leukemia (CML) is a kind of myeloproliferative disorder caused by a constitutively active BCR-ABL tyrosine kinase. Tyrosine kinase inhibitors…”
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