Search Results - "Xu, Zekuan"

Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway by Zhang, Xing, Wang, Sen, Wang, Haixiao, Cao, Jiacheng, Huang, Xiaoxu, Chen, Zheng, Xu, Penghui, Sun, Guangli, Xu, Jianghao, Lv, Jialun, Xu, Zekuan

“…CircRNA has emerged as a new non-coding RNA that plays crucial roles in tumour initiation and development. 'MiRNA sponge' is the most reported role played by…”
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Exosomal miR-21-5p derived from gastric cancer promotes peritoneal metastasis via mesothelial-to-mesenchymal transition by Li, Qiang, Li, Bowen, Li, Qing, Wei, Song, He, Zhongyuan, Huang, Xiaoxu, Wang, Lu, Xia, Yiwen, Xu, Zhipeng, Li, Zheng, Wang, Weizhi, Yang, Li, Zhang, Diancai, Xu, Zekuan

“…Peritoneal metastasis is a primary metastatic route for gastric cancers, and the mechanisms underlying this process are still unclear. Peritoneal mesothelial…”
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Chronic stress promotes gastric cancer progression and metastasis: an essential role for ADRB2 by Zhang, Xuan, Zhang, Yi, He, Zhongyuan, Yin, Kai, Li, Bowen, Zhang, Lu, Xu, Zekuan

“…An increasing number of studies indicate that adrenergic signalling plays a fundamental role in chronic stress-induced tumour progression and metastasis…”
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Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression by Huang, Xiaoxu, Li, Zheng, Zhang, Qiang, Wang, Weizhi, Li, Bowen, Wang, Lu, Xu, Zhipeng, Zeng, Ailiang, Zhang, Xing, Zhang, Xuan, He, Zhongyuan, Li, Qiang, Sun, Guangli, Wang, Sen, Li, Qing, Wang, Linjun, Zhang, Lu, Xu, Hao, Xu, Zekuan

“…Cisplatin (CDDP) treatment is one of the most predominant chemotherapeutic strategies for patients with gastric cancer (GC). A better understanding of the…”
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A novel protein encoded by circMAPK1 inhibits progression of gastric cancer by suppressing activation of MAPK signaling by Jiang, Tianlu, Xia, Yiwen, Lv, Jialun, Li, Bowen, Li, Ying, Wang, Sen, Xuan, Zhe, Xie, Li, Qiu, Shengkui, He, Zhongyuan, Wang, Linjun, Xu, Zekuan

“…A novel type of noncoding RNA, circRNA has been reported to participate in the occurrence and development of diseases through many mechanisms. The MAPK pathway…”
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Circular RNA UBE2Q2 promotes malignant progression of gastric cancer by regulating signal transducer and activator of transcription 3-mediated autophagy and glycolysis by Yang, Jing, Zhang, Xing, Cao, Jiacheng, Xu, Penghui, Chen, Zetian, Wang, Sen, Li, Bowen, Zhang, Lu, Xie, Li, Fang, Lang, Xu, Zekuan

“…Gastric cancer remains the third leading cause of cancer-related mortality worldwide. Emerging evidence has shown that circular RNAs (circRNAs) play a critical…”
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Gastric cancer: Epidemiology, risk factors and prevention strategies by Yang, Lei, Ying, Xiangji, Liu, Shuo, Lyu, Guoqing, Xu, Zekuan, Zhang, Xi, Li, Huichao, Li, Qingyu, Wang, Ning, Ji, Jiafu

“…Gastric cancer (GC) is a global health problem, with more than 1 million people newly diagnosed with GC worldwide each year. GC is more prevalent in less…”
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SRPK1/2 and PP1α exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma by Liu, Hongda, Gong, Zheng, Li, Kangshuai, Zhang, Qun, Xu, Zekuan, Xu, Yunfei

“…The Mnk2 kinase, encoded by MKNK2 gene, plays critical roles in MAPK signaling and was involved in oncogenesis. Human MKNK2 pre-mRNA can be alternatively…”
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Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis by Qiu, Shengkui, Xie, Li, Lu, Chen, Gu, Chao, Xia, Yiwen, Lv, Jialun, Xuan, Zhe, Fang, Lang, Yang, Jing, Zhang, Lu, Li, Zheng, Wang, Weizhi, Xu, Hao, Li, Bowen, Xu, Zekuan

“…Abstract Background Liver metastasis (LM) is a major obstacle to the prognosis of gastric cancer (GC) patients, but the molecular mechanism underlying gastric…”
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Adrenergic modulation of AMPK‑dependent autophagy by chronic stress enhances cell proliferation and survival in gastric cancer by Zhi, Xiaofei, Li, Bowen, Li, Zheng, Zhang, Jiaxuan, Yu, Junbo, Zhang, Lu, Xu, Zekuan

“…Epidemiological data show that chronic stress has adverse effects on the incidence and progression of cancer. As a critical target organ for stress hormones,…”
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CircTHBS1 drives gastric cancer progression by increasing INHBA mRNA expression and stability in a ceRNA- and RBP-dependent manner by Qiu, Shengkui, Li, Bowen, Xia, Yiwen, Xuan, Zhe, Li, Zheng, Xie, Li, Gu, Chao, Lv, Jialun, Lu, Chen, Jiang, Tianlu, Fang, Lang, Xu, Penghui, Yang, Jing, Li, Ying, Chen, Zetian, Zhang, Lu, Wang, Linjun, Zhang, Diancai, Xu, Hao, Wang, Weizhi, Xu, Zekuan

“…Circular RNAs (circRNAs) play vital regulatory roles in the progression of multiple cancers. In our study, transcriptome analysis and self-organizing maps…”
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LncRNA H19 functions as a competing endogenous RNA to regulate AQP3 expression by sponging miR‐874 in the intestinal barrier by Su, Zhaoran, Zhi, Xiaofei, Zhang, Qun, Yang, Li, Xu, Hao, Xu, Zekuan

“…Intestinal barrier dysfunction is a significant clinical problem, which develops in a variety of acute or chronic pathological conditions. In a previous study,…”
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Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis by Zhang, Xing, Li, Zheng, Xuan, Zhe, Xu, Penghui, Wang, Weizhi, Chen, Zheng, Wang, Sen, Sun, Guangli, Xu, Jianghao, Xu, Zekuan

“…Autophagy plays a crucial role in sustaining the homeostasis in various malignant diseases. It has also been reported to promote tumor development in multiple…”
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Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance by Xiao, Jian, Lin, Linling, Luo, Dakui, Shi, Liang, Chen, Wangwang, Fan, Hao, Li, Zengliang, Ma, Xiang, Ni, Peidong, Yang, Li, Xu, Zekuan

“…Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and are frequently dysregulated in cancers. Here, we identify a critical…”
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Circular RNA TMEM87A promotes cell proliferation and metastasis of gastric cancer by elevating ULK1 via sponging miR-142-5p by Wang, Haixiao, Sun, Guangli, Xu, Penghui, Lv, Jialun, Zhang, Xing, Zhang, Lu, Wang, Sen, Cao, Jiacheng, Xia, Yiwen, Xuan, Zhe, Li, Bowen, Huang, Xiaoxu, Jiang, Tianlu, Fang, Lang, Xu, Zekuan

“…Background Circular RNAs (circRNAs) act as vital regulators of gene expression in a variety of cancers. However, the role of circRNAs in gastric cancer (GC)…”
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Long non-coding RNA CCDC144NL-AS1 sponges miR-143-3p and regulates MAP3K7 by acting as a competing endogenous RNA in gastric cancer by Fan, Hao, Ge, Yugang, Ma, Xiang, Li, Zengliang, Shi, Liang, Lin, Linling, Xiao, Jian, Chen, Wangwang, Ni, Peidong, Yang, Li, Xu, Zekuan

“…Gastric cancer (GC) has been one of the most leading cause of cancer-death worldwide. Long non-coding RNAs (lncRNAs) have been found to be related with the…”
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miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer by Jiang, Baofei, Li, Zengliang, Zhang, Wenjie, Wang, Haixiao, Zhi, Xiaofei, Feng, Jin, Chen, Zheng, Zhu, Yi, Yang, Li, Xu, Hao, Xu, Zekuan

“…Background Aquaporin-3 (AQP3) is a water transporting protein which plays an oncogenic role in several malignant tumors. However, its regulatory mechanism…”
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miR-151a-3p-rich small extracellular vesicles derived from gastric cancer accelerate liver metastasis via initiating a hepatic stemness-enhancing niche by Li, Bowen, Xia, Yiwen, Lv, Jialun, Wang, Weizhi, Xuan, Zhe, Chen, Cen, Jiang, Tianlu, Fang, Lang, Wang, Linjun, Li, Zheng, He, Zhongyuan, Li, Qingya, Xie, Li, Qiu, Shengkui, Zhang, Lu, Zhang, Diancai, Xu, Hao, Xu, Zekuan

“…Liver metastasis (LM) severely affects gastric cancer (GC) patients’ prognosis. Small extracellular vesicles (sEVs) play key roles in intercellular…”
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Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress‐independent growth inhibition of pancreatic cancer cells through G2/M cell‐cycle arrest and apoptosis by Li, Wei, Xie, Li, Chen, Zheng, Zhu, Yi, Sun, Yujie, Miao, Yi, Xu, Zekuan, Han, Xiao

“…Cantharidin is an active constituent of mylabris, a traditional Chinese medicine. It is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that…”
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Usefulness of three-dimensional printing of superior mesenteric vessels in right hemicolon cancer surgery by Chen, Yigang, Bian, Linjie, Zhou, Hong, Wu, Danping, Xu, Jie, Gu, Chen, Fan, Xinqi, Liu, Zhequn, Zou, Junyi, Xia, Jiazeng, Xu, Zekuan

“…The anatomy of the superior mesenteric vessels is complex, yet important, for right-sided colorectal surgery. The usefulness of three-dimensional (3D) printing…”
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