Search Results - "Xu, Zaicheng"
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LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity
Published in Circulation (New York, N.Y.) (21-10-2014)“…BACKGROUND—Long noncoding RNAs (lncRNAs) have recently been implicated in many biological processes and diseases. Atherosclerosis is a major risk factor for…”
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Ecological spatial network optimization of carbon sink patches for enhanced carbon sink in Wuhan Metropolitan Area, China
Published in Ecological indicators (01-08-2024)“…•Carbon sink patches in WMA exhibit dense in center and fragmented at periphery.•Steppingstones can improve the robustness of carbon sink networks.•Carbon sink…”
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Research on monitoring and stability evaluation of ground subsidence in gypsum mine goaf
Published in Frontiers in environmental science (04-01-2023)“…The geological disasters caused by the ground deformation of the goaf have brought huge security risks to the ecological environment and society. Therefore, it…”
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Gastrin mediates cardioprotection through angiogenesis after myocardial infarction by activating the HIF-1α/VEGF signalling pathway
Published in Scientific reports (04-08-2021)“…Acute myocardial infarction (MI) is one of the leading causes of death in humans. Our previous studies showed that gastrin alleviated acute myocardial…”
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Liposomal sodium clodronate mitigates radiation-induced lung injury through macrophage depletion
Published in Translational oncology (01-09-2024)“…•M1 macrophage infiltration increased in the lung tissue of RILI mice.•The LC-treated mice showed a reduction in the secretion of pro-inflammatory factors and…”
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Regulation of Cholesterol Homeostasis by a Novel Long Non-coding RNA LASER
Published in Scientific reports (22-05-2019)“…Genome-wide association studies (GWAS) have identified many genetic variants in genes related to lipid metabolism. However, how these variations affect lipid…”
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Genomic features and its potential implication in bone oligometastatic NSCLC
Published in BMC pulmonary medicine (08-02-2023)“…Emerging evidence have demonstrated that oligometastatic non-small cell lung cancer (NSCLC) can achieve clinical benefit from local consolidative therapy. Bone…”
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Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction
Published in EBioMedicine (01-08-2022)“…While the adult mammalian heart undergoes only modest renewal through cardiomyocyte proliferation, boosting this process is considered a promising therapeutic…”
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Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2017)“…Nox4-based NADPH oxidase is a major reactive oxygen species-generating enzyme in the vasculature, but its role in atherosclerosis remains controversial. Our…”
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Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase
Published in Journal of molecular and cellular cardiology (01-03-2016)“…Abstract Nox4-based NADPH oxidase is a major reactive oxygen species-generating enzyme in the vasculature, but its role in atherosclerosis remains…”
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Genetic variants of GRK4 influence circadian rhythm of blood pressure and response to candesartan in hypertensive patients
Published in Clinical and experimental hypertension (1993) (03-10-2021)“…Background: Genetic variants of coding genes related to blood pressure regulation participate in the pathogenesis of hypertension and determines the response…”
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Genomic Characteristics and the Potential Clinical Implications in Oligometastatic Non-Small Cell Lung Cancer
Published in Cancer research and treatment (01-07-2023)“…Oligometastatic non-small cell lung cancer (NSCLC) patients have been increasingly regarded as a distinct group that could benefit from local treatment to…”
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LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis
Published in Biomolecules & biomedicine (01-09-2022)“…The regenerative potential of cardiomyocytes in adult mammals is limited. Previous studies reported that cardiomyocyte proliferation is suppressed by…”
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GW27-e0665 Role of heart-specific long non-coding RNA ANP-AS recruitments p300/CBP in cardiac hypertrophy and the mechanism
Published in Journal of the American College of Cardiology (18-10-2016)“…Methods A microarray was performed to analyze mice heart LncRNAs and mRNAs in response to sham surgery or transverse aortic constriction (TAC) 1 week or 2…”
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Down-regulation of AMPK/PPARδ signalling promotes endoplasmic reticulum stress-induced endothelial dysfunction in adult rat offspring exposed to maternal diabetes
Published in Cardiovascular research (27-07-2022)“…Abstract Aims Exposure to maternal diabetes is associated with increased prevalence of hypertension in the offspring. The mechanisms underlying the prenatal…”
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Prenatal Lipopolysaccharides Exposure Induces Transgenerational Inheritance of Hypertension
Published in Circulation (New York, N.Y.) (04-10-2022)“…Adverse environmental exposure during the prenatal period can lead to diseases in the offspring, including hypertension. Whether or not the hypertensive…”
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Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation
Published in The Journal of clinical investigation (15-12-2021)“…Circular RNAs (circRNAs) have been recently recognized as playing a role in the pathogenesis of vascular remodeling-related diseases by modulating the…”
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LncRNA PSR Regulates Vascular Remodeling Through Encoding a Novel Protein Arteridin
Published in Circulation research (14-10-2022)“…Vascular smooth muscle cells (VSMCs) phenotype switch from contractile to proliferative phenotype is a pathological hallmark in various cardiovascular…”
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BDNF is a prognostic biomarker involved in immune infiltration of lung adenocarcinoma and is associated with brain metastasis
Published in Immunology (01-02-2023)“…Non‐small cell lung cancer (NSCLC) is one of the leading causes of death worldwide. Brain metastases are a common complication of a wide range of human…”
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