Search Results - "Xu, Yong−Nan"
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1
Arp2/3 complex regulates asymmetric division and cytokinesis in mouse oocytes
Published in PloS one (08-04-2011)“…Mammalian oocyte meiotic maturation involves oocyte polarization and a unique asymmetric division, but until now, the underlying mechanisms have been poorly…”
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2
Dihydromyricetin supplementation during in vitro culture improves porcine oocyte developmental competence by regulating oxidative stress
Published in Journal of Reproduction and Development (2023)“…Dihydromyricetin (DHM), a dihydroflavonoid compound, exhibits a variety of biological activities, including antitumor activity. However, the effects of DHM on…”
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3
Insulin interacts with PPARγ agonists to promote bovine adipocyte differentiation
Published in Domestic animal endocrinology (01-07-2024)“…Insulin is a potent adipogenic hormone that triggers a series of transcription factors that regulate the differentiation of preadipocytes into mature…”
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4
Diosmetin Promotes Early Embryonic Development in Pigs by Alleviating Oxidative Stress
Published in Molecular reproduction and development (01-09-2024)“…ABSTRACT Diosmetin (DIOS), a natural flavonoid monomer derived from lemons and present in various plants such as spearmint and spider moss, exhibits…”
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5
Design, synthesis, and biological evaluation of novel 3-substituted imidazo[1,2-a]pyridine and quinazolin-4(3H)-one derivatives as PI3Kα inhibitors
Published in European journal of medicinal chemistry (20-10-2017)“…Phosphatidylinositol 3-kinase (PI3K) is a pivotal regulator of intracellular signaling pathways and considered as a promising target in the development of a…”
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6
Improving the developmental competences of porcine parthenogenetic embryos by Notoginsenoside R1‐induced enhancement of mitochondrial activity and alleviation of proapoptotic events
Published in Reproduction in domestic animals (01-11-2023)“…Abstract Notoginsenoside R1 (NGR1), derived from the Panax notoginseng root and rhizome, exhibits diverse pharmacological influences on the brain, neurons, and…”
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7
Mangiferin improves early porcine embryonic development by reducing oxidative stress
Published in Reproduction in domestic animals (01-04-2024)“…Mangiferin (MGN) is primarily found in the fruits, leaves, and bark of plants of the Anacardiaceae family, including mangoes. MGN exhibits various…”
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Oroxin A reduces oxidative stress, apoptosis, and autophagy and improves the developmental competence of porcine embryos in vitro
Published in Reproduction in domestic animals (01-10-2022)“…Oroxin A (OA) is a flavonoid isolated from Oroxylum indicum (L.) Kurz that has various biological activities, including antioxidant activities. This study…”
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9
Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents
Published in Bioorganic & medicinal chemistry (01-07-2017)“…New series of phthalimides were synthesized including the C7-alkyl chain as a key finding and structure-activity study with the inhibition of nitric oxide…”
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10
Melatonin Supplementation during In Vitro Maturation of Porcine Oocytes Alleviates Oxidative Stress and Endoplasmic Reticulum Stress Induced by Imidacloprid Exposure
Published in Animals (Basel) (11-08-2023)“…Imidacloprid (IMI) is an endogenous neonicotinoid insecticide widely used in agriculture and has attracted researchers’ attention because of its risks to the…”
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11
Wedelolactone facilitates the early development of parthenogenetically activated porcine embryos by reducing oxidative stress and inhibiting autophagy
Published in PeerJ (San Francisco, CA) (25-07-2022)“…Wedelolactone (WDL) is a coumaryl ether compound extracted from the traditional Chinese medicinal plant, L. It is a natural polyphenol that exhibits a variety…”
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12
Enhancing antioxidant levels and mitochondrial function in porcine oocyte maturation and embryonic development through notoginsenoside R1 supplementation
Published in Reproduction in domestic animals (01-06-2024)“…This study examines the impact of Notoginsenoside R1 (NGR1), a compound from Panax notoginseng, on the maturation of porcine oocytes and their embryonic…”
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13
JMY functions as actin nucleation-promoting factor and mediator for p53-mediated DNA damage in porcine oocytes
Published in PloS one (03-10-2014)“…Junction-mediating and regulatory protein(JMY) is a multifunctional protein with roles in the transcriptional co-activation of p53 and the regulation of actin…”
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14
BDE-47 Induces Mitochondrial Dysfunction and Endoplasmic Reticulum Stress to Inhibit Early Porcine Embryonic Development
Published in Animals (Basel) (13-07-2023)“…Widely used as a flame retardant, 2,2'4,4'-tetrabromodiphenyl ether (BDE-47) is a persistent environmental pollutant with toxicological effects, including…”
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15
Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells
Published in Stem cells international (29-09-2023)“…Brain organoids have been considered as an advanced platform for in vitro disease modeling and drug screening, but numerous roadblocks exist, such as lack of…”
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Supplementation with Eupatilin during In Vitro Maturation Improves Porcine Oocyte Developmental Competence by Regulating Oxidative Stress and Endoplasmic Reticulum Stress
Published in Animals (Basel) (01-01-2024)“…Eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone) is a flavonoid derived from plants that has beneficial biological activities, such as anti-apoptotic,…”
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17
The Rho-GTPase effector ROCK regulates meiotic maturation of the bovine oocyte via myosin light chain phosphorylation and cofilin phosphorylation
Published in Molecular reproduction and development (01-11-2015)“…SUMMARY Oocyte meiosis involves a unique asymmetric division involving spindle movement from the central cytoplasm to the cortex, followed by polar body…”
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18
Chrysoeriol Improves In Vitro Porcine Embryo Development by Reducing Oxidative Stress and Autophagy
Published in Veterinary sciences (01-02-2023)“…Chrysoeriol (CHE) is a flavonoid substance that exists in many plants. It has various physiological and pharmacological effects, including anti-inflammatory,…”
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Chrysoeriol Improves the Early Development Potential of Porcine Oocytes by Maintaining Lipid Homeostasis and Improving Mitochondrial Function
Published in Antioxidants (01-01-2024)“…Our previous study established that chrysoeriol (CHE) can reduce reactive oxygen species (ROS) accumulation, apoptosis, and autophagy in vitro culture (IVC) of…”
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Citrinin exposure affects oocyte maturation and embryo development by inducing oxidative stress-mediated apoptosis
Published in Oncotarget (23-05-2017)“…Citrinin is one of the mycotoxins and has been shown to have various toxic effects in animals and humans. Although previous study showed the toxic effects of…”
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