Search Results - "Xu, Xiaojiang"

scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells by Wang, Zhengpin, Xu, Xiaojiang

“…In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both high sequence…”
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Trace electrosprayed nanopolystyrene facilitated dispersion of multiwalled carbon nanotubes: Simultaneously strengthening and toughening epoxy by Gu, Hongbo, Zhang, Hongyuan, Ma, Chao, Xu, Xiaojiang, Wang, Yaqing, Wang, Zicheng, Wei, Renbo, Liu, Hu, Liu, Chuntai, Shao, Qian, Mai, Xianmin, Guo, Zhanhu

“…The search of multifunctional epoxy nanocomposites with both strength and toughness combined with smart features such as electrical conductivity is essential…”
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Polyaniline crystalline nanostructures dependent negative permittivity metamaterials by Xu, Xiaojiang, Fu, Qiangang, Gu, Hongbo, Guo, Ying, Zhou, Heng, Zhang, Jiaoxia, Pan, Duo, Wu, Shide, Dong, Mengyao, Guo, Zhanhu

“…Herein, we report the preparation of polyaniline (PANI) crystalline nanostructures and their dependent negative permittivity. By controlling the types of doped…”
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Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice by Wang, Zhengpin, Xu, Xiaojiang, Li, Jian-Liang, Palmer, Cameron, Maric, Dragan, Dean, Jurrien

“…Spermatogonial stem cells (SSCs) have the dual capacity to self-renew and differentiate into progenitor spermatogonia that develop into mature spermatozoa…”
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Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway by Shats, Igor, Williams, Jason G., Liu, Juan, Makarov, Mikhail V., Wu, Xiaoyue, Lih, Fred B., Deterding, Leesa J., Lim, Chaemin, Xu, Xiaojiang, Randall, Thomas A., Lee, Ethan, Li, Wenling, Fan, Wei, Li, Jian-Liang, Sokolsky, Marina, Kabanov, Alexander V., Li, Leping, Migaud, Marie E., Locasale, Jason W., Li, Xiaoling

“…Nicotinamide adenine dinucleotide (NAD), a cofactor for hundreds of metabolic reactions in all cell types, plays an essential role in metabolism, DNA repair,…”
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Estrogen Deficiency Promotes Hepatic Steatosis via a Glucocorticoid Receptor-Dependent Mechanism in Mice by Quinn, Matthew A., Xu, Xiaojiang, Ronfani, Melania, Cidlowski, John A.

“…Glucocorticoids (GCs) are master regulators of systemic metabolism. Intriguingly, Cushing’s syndrome, a disorder of excessive GCs, phenocopies several…”
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Development of interactive guidance for cold exposure using a thermoregulatory model by Xu, Xiaojiang, Rioux, Timothy, Friedl, Karl, Gonzalez, Julio, Castellani, John

“…For decades, the Wind Chill Temperature Index (WCT) and its various iterations have been used to assess the risk of frostbite on unclothed body parts. This…”
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Determination of the cooling capacity for body ventilation system by Xu, Xiaojiang, Gonzalez, Julio

“…Body ventilation systems (BVS) are effective in reducing heat strain, but the amount of heat that a BVS removes from a human body is unclear. The purpose of…”
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Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice by Oakley, Robert H, Cruz-Topete, Diana, He, Bo, Foley, Julie F, Myers, Page H, Xu, Xiaojiang, Gomez-Sanchez, Celso E, Chambon, Pierre, Willis, Monte S, Cidlowski, John A

“…Stress is increasingly associated with heart dysfunction and is linked to higher mortality rates in patients with cardiometabolic disease. Glucocorticoids are…”
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Global Gene Expression Analysis in Human Uterine Epithelial Cells Defines New Targets of Glucocorticoid and Estradiol Antagonism by WHIRLEDGE, Shannon, XIAOJIANG XU, CIDLOWSKI, John A

“…In preparation for embryo implantation and pregnancy, the uterine epithelium undergoes a genomic and biological transition that mediates adhesion and invasion…”
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Ebola Response: Modeling the Risk of Heat Stress from Personal Protective Clothing by Potter, Adam W, Gonzalez, Julio A, Xu, Xiaojiang

“…A significant number of healthcare workers have responded to aid in the relief and containment of the 2013 Ebola virus disease (EVD) outbreak in West Africa…”
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Multi-omics analysis reveals the molecular basis of flavonoid accumulation in fructus of Gardenia (Gardenia jasminoides Ellis) by Chen, Jianrong, Tang, Weizhuo, Li, Chunyan, Kuang, Ding, Xu, Xiaojiang, Gong, Yuan, Liu, Fang, Gao, Song

“…Abstract Background The fruits of Gardenia are rich in flavonoids and geniposides, which have various pharmacological effects such as antioxidant,…”
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Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response by Wang, Yu, Liang, Yiyi, Xu, Haiyan, Zhang, Xiao, Mao, Tiebo, Cui, Jiujie, Yao, Jiayu, Wang, Yongchao, Jiao, Feng, Xiao, Xiuying, Hu, Jiong, Xia, Qing, Zhang, Xiaofei, Wang, Xujun, Sun, Yongwei, Fu, Deliang, Shen, Lei, Xu, Xiaojiang, Xue, Jing, Wang, Liwei

“…The current pathological and molecular classification of pancreatic ductal adenocarcinoma (PDAC) provides limited guidance for treatment options, especially…”
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RDense: A Protein-RNA Binding Prediction Model Based on Bidirectional Recurrent Neural Network and Densely Connected Convolutional Networks by Li, Zhong, Zhu, Jiapeng, Xu, Xiaojiang, Yao, Yuhua

“…Complexes formed by proteins binding to RNAs are essential in biological processes, and can also be useful for identifying causal disease variants, gene…”
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Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye by Kadmiel, Mahita, Janoshazi, Agnes, Xu, Xiaojiang, Cidlowski, John A.

“…Glucocorticoids play diverse roles in almost all physiological systems of the body, including both anti-inflammatory and immunosuppressive roles. Synthetic…”
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Reproductive toxicity of low level bisphenol A exposures in a two-generation zebrafish assay: Evidence of male-specific effects by Chen, Jiangfei, Xiao, Yanyan, Gai, Zengxin, Li, Rong, Zhu, Zixu, Bai, Chenglian, Tanguay, Robert L., Xu, Xiaojiang, Huang, Changjiang, Dong, Qiaoxiang

“…•We used the zebrafish model to assess reproductive toxicity of chronic low level BPA exposure.•BPA exposure resulted in female-biased sex ratio, decreased…”
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Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression by Xu, Xiaojiang, Hoang, Stephen, Mayo, Marty W, Bekiranov, Stefan

“…In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form…”
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Correction: Iguratimod attenuated fbrosis in systemic sclerosis via targeting early growth response 1 expression by Shen, Lichong, Yin, Hanlin, Sun, Li, Zhang, Zhiliang, Jin, Yuyang, Cao, Shan, Fu, Qiong, Fan, Chaofan, Bao, Chunde, Lu, Liangjing, Zhan, Yifan, Xu, Xiaojiang, Chen, Xiaoxiang, Yan, Qingran

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Iguratimod attenuated fibrosis in systemic sclerosis via targeting early growth response 1 expression by Shen, Lichong, Yin, Hanlin, Sun, Li, Zhang, Zhiliang, Jin, Yuyang, Cao, Shan, Fu, Qiong, Fan, Chaofan, Bao, Chunde, Lu, Liangjing, Zhan, Yifan, Xu, Xiaojiang, Chen, Xiaoxiang, Yan, Qingran

“…The early growth response 1 (EGR1) is a central transcription factor involved in systemic sclerosis (SSc) pathogenesis. Iguratimod is a synthesized…”
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SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B by Fan, Wei, Tang, Shuang, Fan, Xiaojuan, Fang, Yi, Xu, Xiaojiang, Li, Leping, Xu, Jian, Li, Jian-Liang, Wang, Zefeng, Li, Xiaoling

“…Sphingolipids are important structural components of cell membranes and prominent signaling molecules controlling cell growth, differentiation, and apoptosis…”
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