Search Results - "Xu, Xiaochuan C"

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs by Lawson, William E, Cheng, Dong-Sheng, Degryse, Amber L, Tanjore, Harikrishna, Polosukhin, Vasiliy V, Xu, Xiaochuan C, Newcomb, Dawn C, Jones, Brittany R, Roldan, Juan, Lane, Kirk B, Morrisey, Edward E, Beers, Michael F, Yull, Fiona E, Blackwell, Timothy S

“…Evidence of endoplasmic reticulum (ER) stress has been found in lungs of patients with familial and sporadic idiopathic pulmonary fibrosis. We tested whether…”
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Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis by Tanjore, Harikrishna, Xu, Xiaochuan C, Polosukhin, Vasiliy V, Degryse, Amber L, Li, Bo, Han, Wei, Sherrill, Taylor P, Plieth, David, Neilson, Eric G, Blackwell, Timothy S, Lawson, William E

“…Lung fibroblasts are key mediators of fibrosis resulting in accumulation of excessive interstitial collagen and extracellular matrix, but their origins are not…”
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Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis by Degryse, Amber L, Tanjore, Harikrishna, Xu, Xiaochuan C, Polosukhin, Vasiliy V, Jones, Brittany R, McMahon, Frank B, Gleaves, Linda A, Blackwell, Timothy S, Lawson, William E

“…Single-dose intratracheal bleomycin has been instrumental for understanding fibrotic lung remodeling, but fails to recapitulate several features of idiopathic…”
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Protein Substrate Alters Cell Physiology in Primary Culture of Vocal Fold Epithelial Cells by Kimball, Emily E, Sayce, Lea, Xu, Xiaochuan C, Kruszka, Chase M, Rousseau, Bernard

“…The basement membrane interacts directly with the vocal fold epithelium. Signaling between the basement membrane and the epithelium modulates gene regulation,…”
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β-Catenin in the Alveolar Epithelium Protects from Lung Fibrosis after Intratracheal Bleomycin by TANJORE, Harikrishna, DEGRYSE, Amber L, MCMAHON, Frank B, GLEAVES, Linda A, BLACKWELL, Timothy S, LAWSON, William E, CROSSNO, Peter F, XU, Xiaochuan C, MCCONAHA, Melinda E, JONES, Brittany R, POLOSUKHIN, Vasiliy V, BRYANT, Andrew J, CHENG, Dong-Sheng, NEWCOMB, Dawn C

“…Alveolar epithelial cells (AECs) play central roles in the response to lung injury and the pathogenesis of pulmonary fibrosis. We aimed to determine the role…”
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TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment by Degryse, Amber L, Tanjore, Harikrishna, Xu, Xiaochuan C, Polosukhin, Vasiliy V, Jones, Brittany R, Boomershine, Chad S, Ortiz, Camila, Sherrill, Taylor P, McMahon, Frank B, Gleaves, Linda A, Blackwell, Timothy S, Lawson, William E

“…The response of alveolar epithelial cells (AECs) to lung injury plays a central role in the pathogenesis of pulmonary fibrosis, but the mechanisms by which…”
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Telomerase deficiency does not alter bleomycin-induced fibrosis in mice by Degryse, Amber L., Xu, Xiaochuan C., Newman, J. Luke, Mitchell, Daphne B., Tanjore, Harikrishna, Polosukhin, Vasiliy V., Jones, Brittany R., McMahon, Frank B., Gleaves, Linda A., Phillips, John A., Cogan, Joy D., Blackwell, Timothy S., Lawson, William E.

“…ABSTRACT Idiopathic pulmonary fibrosis (IPF) is characterized by interstitial lung infiltrates, dyspnea, and progressive respiratory failure. Reports linking…”
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[Beta]-Catenin in the Alveolar Epithelium Protects from Lung Fibrosis after Intratracheal Bleomycin by Tanjore, Harikrishna, Degryse, Amber L, Crossno, Peter F, Xu, Xiaochuan C, McConaha, Melinda E, Jones, Brittany R, Polosukhin, Vasiliy V, Bryant, Andrew J, Cheng, Dong-Sheng, Newcomb, Dawn C, McMahon, Frank B, Gleaves, Linda A, Blackwell, Timothy S, Lawson, William E

“…Alveolar epithelial cells (AECs) play central roles in the response to lung injury and the pathogenesis of pulmonary fibrosis. We aimed to determine the role…”
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