Search Results - "Xu, Wenrong"
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CircRNA: a rising star in gastric cancer
Published in Cellular and molecular life sciences : CMLS (01-05-2020)“…In recent years, a large number of circRNAs have been identified in mammalian cells with high-throughput sequencing technologies and bioinformatics. The…”
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Exosomes as a new frontier of cancer liquid biopsy
Published in Molecular cancer (18-02-2022)“…Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for…”
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3
Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration
Published in Molecular cancer (06-10-2018)“…Exosomes are extracellular vesicles that mediate cellular communication in health and diseases. Neutrophils could be polarized to a pro-tumor phenotype by…”
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Exosomes in gastric cancer: roles, mechanisms, and applications
Published in Molecular cancer (15-03-2019)“…Exosomes are nanosized extracellular vesicles that can be released by almost all types of cells. Initially considered as the garbage bins acting to discard…”
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HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis
Published in Cell death & disease (08-04-2022)“…Activated hepatic stellate cells (HSCs) are significant in liver fibrosis. Our past investigations have shown that human umbilical cord mesenchymal stem cells…”
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Engineered Extracellular Vesicles for Cancer Therapy
Published in Advanced materials (Weinheim) (01-04-2021)“…Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of many diseases including cancer. As a result of their natural…”
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Exosomal circRNA: emerging insights into cancer progression and clinical application potential
Published in Journal of hematology and oncology (26-06-2023)“…Exosomal circRNA serves a novel genetic information molecule, facilitating communication between tumor cells and microenvironmental cells, such as immune…”
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Circular RNAs: emerging cancer biomarkers and targets
Published in Journal of experimental & clinical cancer research (02-11-2017)“…CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are abundant in eukaryotic transcripts and show certain levels of tissue…”
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HucMSC‐Exosome Mediated‐Wnt4 Signaling Is Required for Cutaneous Wound Healing
Published in Stem cells (Dayton, Ohio) (01-07-2015)“…Mesenchymal stem cell‐derived exosomes (MSC‐Ex) play important roles in tissue injury repair, however, the roles of MSC‐Ex in skin damage repair and its…”
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Engineered exosome-mediated delivery of circDIDO1 inhibits gastric cancer progression via regulation of MiR-1307-3p/SOCS2 Axis
Published in Journal of translational medicine (21-07-2022)“…Abstract Background Our previous study has identified a novel circRNA (circDIDO1) that is down-regulated in gastric cancer (GC) and significantly inhibits GC…”
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Extracellular vesicles in normal pregnancy and pregnancy‐related diseases
Published in Journal of cellular and molecular medicine (01-04-2020)“…Extracellular vesicles (EVs) are nanosized, membranous vesicles released by almost all types of cells. Extracellular vesicles can be classified into distinct…”
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Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell-Derived Exosomes in Cell-Free Therapy
Published in Stem cells international (14-05-2022)“…Mesenchymal stem cells (MSCs) have been widely applied to regenerative medicine owing to their multiple differentiation, self-renewal, and immunomodulatory…”
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Improved therapeutics of modified mesenchymal stem cells: an update
Published in Journal of translational medicine (30-01-2020)“…Mesenchymal stromal cells (MSCs) have attracted intense interest due to their powerful intrinsic properties of self-regeneration, immunomodulation and…”
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Exosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression
Published in Cell death & disease (02-04-2020)“…Long non-coding RNAs (LncRNAs) have been suggested as important regulators of cancer development and progression in non-small cell lung cancer (NSCLC)…”
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The emerging roles of exosomes in tumor–stroma interaction
Published in Journal of Cancer Research & Clinical Oncology (01-09-2016)“…Purpose The tumor–stroma interaction is critical for the development and progression of cancer. Cancer-associated fibroblasts (CAFs), one of the major…”
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Journal Article Book Review -
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CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability
Published in Molecular cancer (12-08-2021)“…Circular RNAs (circRNAs) play important roles in cancer development and progression. The purpose of this study is to identify aberrantly expressed circRNAs in…”
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Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)
Published in International journal of oncology (01-09-2016)“…Neutrophils are predominant immune cells that protect the host from microbial infection. The roles of neutrophils in tumor have long been ignored due to their…”
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Human Umbilical Cord Mesenchymal Stem Cell Exosomes Enhance Angiogenesis Through the Wnt4/β‐Catenin Pathway
Published in Stem cells translational medicine (01-05-2015)“…Human umbilical cord mesenchymal stem cells (hucMSCs) and their exosomes have been considered as potential therapeutic tools for tissue regeneration; however,…”
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Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis
Published in Stem cells and development (15-03-2013)“…Mesenchymal stem cells (MSCs) have been considered as an attractive tool for the therapy of diseases. Exosomes excreted from MSCs can reduce myocardial…”
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Lymph node metastasis-derived gastric cancer cells educate bone marrow-derived mesenchymal stem cells via YAP signaling activation by exosomal Wnt5a
Published in Oncogene (25-03-2021)“…Lymph node metastasis (LNM), a common metastatic gastric-cancer (GC) route, is closely related to poor prognosis in GC patients. Bone marrow-derived…”
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