Search Results - "Xu, Shengzhen"

Selective probes targeting c-MYC Pu22 G-quadruplex and their application in live mice imaging by Yu, Zhuo, Huang, Wenbo, Shi, Liqiao, Ke, Shaoyong, Xu, Shengzhen

“…Several probes containing benzothiazole-guided conjugated systems (BGCS) were designed and synthesized, and two molecules (BGCS5 and BGCS6) of which were…”
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BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers by Gao, Chao, Liu, Zhu, Hou, Haitao, Ding, Jieqin, Chen, Xin, Xie, Congbao, Song, Zibing, Hu, Zhe, Feng, Mingqian, Mohamed, Hany I, Xu, Shengzhen, Parkinson, Gary N, Haider, Shozeb, Wei, Dengguo

“…Abstract A single G-quadruplex forming sequence from the human telomere can adopt six distinct topologies that are inter-convertible under physiological…”
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3-Butyl-2-propylamino-1-benzothieno[3,2- d ]pyrimidin-4(3 H )-one by Xu, Shengzhen

“…In the title compound, C17H21N3OS, the propyl and butyl groups are disordered over two positions; site occupation factors are 0.304 (10) and 0.696 (10). The…”
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Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors by Li, Huangyong, Chen, Changshui, Xu, Shengzhen, Cao, Xiufang

“…A series of novel cycloalkylthieno[2,3-d]pyrimidinone derivatives have been conveniently synthesized via three steps including G-3CR, heterocyclization, and…”
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The discovery of the novel lead compound of N-nitroureas target on acetohydroxyacid synthase by Jin, Jingnan, Ma, Hongju, Cao, Xiufang, Xu, Shengzhen, Li, Jianhong, Zhang, Qingye, Chen, Changshui

“…The optimized compounds (shown in yellow stick) binding mode in the active site of AtAHAS. [Display omitted] ► A novel N-nitrourea compound has been discovered…”
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Oligo(ethylene glycol)-Functionalized Ratiometric Fluorescent Probe for the Detection of Hydrazine in Vitro and in Vivo by Li, Jun, Cui, Yuanchao, Bi, Chenxi, Feng, Shaoqiong, Yu, Fengzhen, Yuan, En, Xu, Shengzhen, Hu, Zhe, Sun, Qi, Wei, Dengguo, Yoon, Juyoung

“…Hydrazine induced toxicity causes serious harm to the health of humans. The detection of N2H4 in vitro and in vivo has attracted a great deal of attention,…”
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Benzothiazole-based colorimetric chemosensors bearing naphthol aldehyde unit: Synthesis, characterization, selective detection of hypochlorite and its application as test strips by Yu, Zhuo, Huang, Wenbo, Xu, Shengzhen, Ke, Shaoyong

“…•BTNA1 can be utilized as a colorimetric chemosensor for detection of ClO− anion.•BTNA1 is novel benzothiazole-based colorimetric chemosensors bearing naphthol…”
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Selective recognition of c-MYC Pu22 G-quadruplex by a fluorescent probe by Zhai, Qianqian, Gao, Chao, Ding, Jieqin, Zhang, Yashu, Islam, Barira, Lan, Wenxian, Hou, Haitao, Deng, Hua, Li, Jun, Hu, Zhe, Mohamed, Hany I, Xu, Shengzhen, Cao, Chunyang, Haider, Shozeb M, Wei, Dengguo

“…Abstract Nucleic acid mimics of fluorescent proteins can be valuable tools to locate and image functional biomolecules in cells. Stacking between the internal…”
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Asymmetric syntheses and bio-evaluation of novel chiral esters derived from substituted tetrafluorobenzyl alcohol by Xu, Shengzhen, Li, Huangyong, Wang, Xiaohui, Chen, Changshui, Cao, Minhui, Cao, Xiufang

“…A series of novel chiral esters derived from tetrafluorobenzyl alcohol were designed and distereoselectively synthesized, and the respective pairs of…”
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Novel lead compound optimization and synthesized based on the target structure of Xanthomonas oryzae pv. oryzae GlmU by Qi, Xiaojuan, Deng, Wenjun, Gao, Min, Mao, Bangqiang, Xu, Shengzhen, Chen, Changshui, Zhang, Qingye

“…•Three types of novel target compounds were optimized and synthesized.•All of the target compounds displayed IC50 values in the 10.82–23.31 µM range, the…”
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Clinicopathological significance of Sox2 expression in patients with breast cancer: a meta-analysis by Zheng, Yan, Qin, Biyong, Li, Fang, Xu, Shengzhen, Wang, Shanshan, Li, Li

“…Sex-determining region Y-box protein 2 (Sox2), an embryonic transcription factor located at chromosome 3q26.33, has been frequently demonstrated to be an…”
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N-Nitrourea Derivatives as Novel Potential Fungicides against Rhizoctonia solani: Synthesis, Antifungal Activities, and 3D-QSAR by Cao, Xiufang, Xu, Shengzhen, Li, Xuegang, Shen, Xiaoxia, Zhang, Qingye, Li, Jianhong, Chen, Changshui

“…A series of N‐nitrourea derivatives bearing various aryl substituents were conveniently obtained via three steps including nitration, carbamic chlorination,…”
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Novel N-nitroacetamide derivatives derived from 2,4-D: Design, synthesis, bioevaluation, and prediction of mechanism of action by Wei, Zengjun, Chen, Changshui, Shi, Libin, Jin, Jingnan, Zhang, Qingye, Xu, Shengzhen, Cao, Xiufang, Yue, Xiali

“…A series of novel N-nitroacetamides derivatives targeting AHAS enzyme have been obtained and evaluated, and some of the target compounds displayed good…”
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Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors by Li, Huangyong, Chen, Changshui, Xu, Shengzhen, Cao, Xiufang

“…A series of novel cycloalkylthieno[2,3-d]pyrimidinone derivatives have been conveniently synthesized via three steps including G-3CR, heterocyclization, and…”
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Facile synthesis and biological evaluation of novel fluorine-containing N-nitro-N′-substituted phenylurea by Wang, Yunchun, Bai, Zhongyuan, Wei, Zengjun, Xu, Shengzhen, Li, Xuegang, Li, Jianhong, Cao, Xiufang, Chen, Changshui

“…Twenty-two novel N -nitro- N ′-substituted phenyl- N -(2,6-dibromo-4-fluorophenyl)urea derivatives were designed and synthesized via a simple and convenient…”
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Cycloalkyl substituted N-nitrourea derivatives: a convenient synthesis and biological evaluation by Bai, Zhongyuan, Wei, Zengjun, Wang, Yunchun, Xu, Shengzhen, Li, Xuegang, Chen, Changshui, Cao, Xiufang

“…A series of N -nitrourea derivatives bearing various cycloalkyl were conveniently obtained via three steps including nitration, carbamic chlorination, and…”
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