Search Results - "Xu, Qiongming"
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Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo by modulating toll-like receptor 4 dimerization and NF-kB/MAPKs signaling pathways
Published in Phytomedicine (Stuttgart) (01-04-2020)“…Ginsenoside Rb1, the main active constituent of Panax ginseng, displays significant anti-inflammatory activity, although the mechanism has not been clearly…”
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Naturally occurring physalins from the genus Physalis: A review
Published in Phytochemistry (Oxford) (01-11-2021)“…Physalins, including physalins and neophysalins, are a class of highly oxygenated ergostane-type steroids. They are commonly known by the name of…”
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Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway
Published in Chinese medicine (18-01-2021)“…Despite the increased morbidity of ulcerative colitis (UC) in the developing countries, available treatments remain unsatisfactory. Therefore, it is urgent to…”
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Anti-inflammatory and cytotoxic withanolides from Physalis minima
Published in Phytochemistry (Oxford) (01-11-2018)“…Six undescribed withanolides were isolated and characterized during the investigation of anti-inflammatory and cytotoxic constituents from the whole plants of…”
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Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis
Published in Molecules (Basel, Switzerland) (13-06-2018)“…: Schistosomiasis is a major neglected disease for which the current control strategy involves mass treatment with praziquantel, the only available drug…”
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Simultaneous determination of savaside A, acteoside, and isoacteoside in rat plasma by UHPLC–MS/MS: Comparative pharmacokinetic and bioavailability characteristics of Monochasma savatieri via different routes of administration
Published in Journal of separation science (01-12-2018)“…Phenylethanoid glycosides are the bioactive components in Monochasma savatieri that primarily contains savaside A, acteoside, and isoacteoside. Pharmacological…”
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Ginsenoside Rb1 exerts therapeutic effects on ulcerative colitis through regulating the Nrf2/PIP2/NLRP3 inflammasome signaling pathway
Published in Journal of functional foods (01-03-2023)“…[Display omitted] •GRb1 has a therapeutic effect on UC.•GRb1 plays a therapeutic role in UC by targeting Nrf2 and regulating the Nrf2/PIP2/NLRP3 pathway.•GRb1…”
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Anemoside B4 Protects against Acute Lung Injury by Attenuating Inflammation through Blocking NLRP3 Inflammasome Activation and TLR4 Dimerization
Published in Journal of immunology research (2020)“…Acute lung injury (ALI) is an acute inflammatory process in the lung parenchyma. Anemoside B4 (B4) was isolated from Pulsatilla, a plant-based drug against…”
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The rapid discovery and identification of physalins in the calyx of Physalis alkekengi L.var.franchetii (Mast.) Makino using ultra-high performance liquid chromatography–quadrupole time of flight tandem mass spectrometry together with a novel three-step data mining strategy
Published in Journal of Chromatography A (26-09-2014)“…•Fragmentation pathways and rules of physalins were obtained.•Diagnostic ions for rapid screening of physalins were determined.•Diagnostic ions for…”
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Anemoside B4 protects against Klebsiella pneumoniae - and influenza virus FM1-induced pneumonia via the TLR4/Myd88 signaling pathway in mice
Published in Chinese medicine (02-07-2020)“…Pneumonia refers to the inflammation of the terminal airway, alveoli and pulmonary interstitium, which can be caused by pathogenic microorganisms, physical and…”
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Novel compounds in fruits of coriander (Coşkuner & Karababa) with anti-inflammatory activity
Published in Journal of functional foods (01-10-2020)“…[Display omitted] •Four new compounds were identified in Coriander (Coriandrum Sativum L.).•Compound 3 exhibited a significant anti-inflammatory…”
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Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4/MyD88 signaling pathway
Published in Chinese medicine (02-03-2020)“…Cryptotanshinone (CPT), as a major component of Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the…”
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Anti-inflammatory Withanolides from Physalis minima
Published in ACS omega (02-06-2020)“…Five new withanolides ( 1–5 ) along with five known ones ( 6–10 ) were isolated from the whole plants of Physalis minima Linn. The chemical structures of the…”
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Physalins and withanolides from the fruits of Physalis alkekengi L. var. franchetii (Mast.) Makino and the inhibitory activities against human tumor cells
Published in Phytochemistry letters (01-12-2014)“…•Three new steroids (1–3) and seven known steroids (4–10) were isolated from the fruits of Physalis alkekengi.•All compounds were characterized by…”
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Anti-inflammatory and immune-modulatory properties of anemoside B4 isolated from Pulsatilla chinensis in vivo
Published in Phytomedicine (Stuttgart) (01-11-2019)“…Pulsatilla chinensis is commonly used for the treatment of cancers and inflammatory disorders in China. Our recent studies showed that anemoside B4, its major…”
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Ginsenoside Rb1 is an immune-stimulatory agent with antiviral activity against enterovirus 71
Published in Journal of ethnopharmacology (10-02-2021)“…According to the theory of traditional Chinese medicine, the main pathogenesis of severe hand, foot and mouth disease (HFMD) is that the heat and wet poisons…”
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Induction of an MLKL mediated non-canonical necroptosis through reactive oxygen species by tanshinol A in lung cancer cells
Published in Biochemical pharmacology (01-01-2020)“…[Display omitted] Recent discoveries revealed several types of programmed necrosis, such as necroptosis, ferroptosis, pyroptosis, etc. Necroptosis is mediated…”
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Anemoside B4 attenuates nephrotoxicity of cisplatin without reducing anti-tumor activity of cisplatin
Published in Phytomedicine (Stuttgart) (15-03-2019)“…Cisplatin is a highly effective chemotherapeutic agent commonly used in the treatment of a wide variety of malignancies. However, its clinical usage is…”
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Rosamultin ameliorates radiation injury via promoting DNA injury repair and suppressing oxidative stress in vitro and in vivo
Published in Chemico-biological interactions (25-04-2024)“…Radiotherapy remains the preferred treatment option for cancer patients with the advantages of broad indications and significant therapeutic effects. However,…”
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Isoflavones from green vegetable soya beans and their antimicrobial and antioxidant activities
Published in Journal of the science of food and agriculture (01-03-2018)“…BACKGROUND Green vegetable soya beans, known as Maodou in China, are supplied as vegetable‐type fruits of the soybean plant. Previous study indicated that…”
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