Search Results - "Xu, Qiao"
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Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species
Published in Frontiers in neuroscience (21-06-2019)“…Alzheimer disease (AD) represents an oncoming epidemic that without an effective treatment promises to exact extraordinary human and financial burdens. Studies…”
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Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses
Published in Frontiers in neuroscience (07-05-2019)“…Alzheimer disease (AD) represents an oncoming epidemic that without an effective treatment promises to exact extraordinary financial and emotional burdens…”
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4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects
Published in Nature communications (08-11-2019)“…Activated macrophages switch from oxidative phosphorylation to aerobic glycolysis, similar to the Warburg effect, presenting a potential therapeutic target in…”
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Coordination engineering of iridium nanocluster bifunctional electrocatalyst for highly efficient and pH-universal overall water splitting
Published in Nature communications (25-08-2020)“…Water electrolysis offers a promising energy conversion and storage technology for mitigating the global energy and environmental crisis, but there still lack…”
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Endothelial dysfunction in diabetes and hypertension: Role of microRNAs and long non-coding RNAs
Published in Life sciences (1973) (15-11-2018)“…The vascular endothelium acts as a barrier between the blood flow and the inner lining of the vessel wall, and it functions as a filtering machinery to filter…”
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Superimposed Pilots are Beneficial for Mitigating Pilot Contamination in Cell-Free Massive MIMO
Published in IEEE communications letters (01-01-2021)“…In this letter, we present the first study for uplink cell-free massive multi-input multi-output (MIMO) systems with superimposed pilots (SPs). Closed-form…”
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Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ‐Secretase Modulator
Published in Annals of neurology (01-08-2023)“…Objective The retromer complex plays an essential role in intracellular endosomal sorting. Deficits in the retromer complex are linked to enhanced Aβ…”
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A general strategy for preparing pyrrolic-N4 type single-atom catalysts via pre-located isolated atoms
Published in Nature communications (23-11-2021)“…Single-atom catalysts (SACs) have been applied in many fields due to their superior catalytic performance. Because of the unique properties of the…”
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Atomically-precise dopant-controlled single cluster catalysis for electrochemical nitrogen reduction
Published in Nature communications (01-09-2020)“…The ability to precisely engineer the doping of sub-nanometer bimetallic clusters offers exciting opportunities for tailoring their catalytic performance with…”
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Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy
Published in Nature communications (08-03-2018)“…Dominant mutations in glycyl-tRNA synthetase (GlyRS) cause a subtype of Charcot-Marie-Tooth neuropathy (CMT2D). Although previous studies have shown that GlyRS…”
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The Role of TGF-β and Its Receptors in Gastrointestinal Cancers
Published in Translational oncology (01-03-2019)“…Early detection of gastrointestinal tumors improves patient survival. However, patients with these tumors are typically diagnosed at an advanced stage and have…”
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Ultrastable single-atom gold catalysts with strong covalent metal-support interaction (CMSI)
Published in Nano research (01-09-2015)“…Supported noble metal nanoparticles (including nanoclusters) are widely used in many industrial catalytic processes. While the finely dispersed nanostructures…”
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Three-dimensional open nano-netcage electrocatalysts for efficient pH-universal overall water splitting
Published in Nature communications (25-10-2019)“…High-efficiency water electrolysis is the key to sustainable energy. Here we report a highly active and durable RuIrO x ( x ≥ 0) nano-netcage catalyst formed…”
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14
Impact of fruit-tree shade intensity on the growth, yield, and quality of intercropped wheat
Published in PloS one (02-04-2019)“…Agroforestry is a common traditional practice in China-especially in the southern Xinjiang of Northwest China. However, the productivity of many agroforestry…”
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γ‐Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer‐Related Pathologies in a Mouse Model of Down Syndrome
Published in Annals of neurology (01-08-2024)“…Objectives Due to increased gene dose for the amyloid precursor protein (APP), elderly adults with Down syndrome (DS) are at a markedly increased risk of…”
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Wafer Defect Pattern Recognition and Analysis Based on Convolutional Neural Network
Published in IEEE transactions on semiconductor manufacturing (01-11-2019)“…Wafer map defect pattern contains the critical information about semiconductor manufacturing, effective defect analysis technology can improve the yield of…”
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Au16Cd16(SC6H11)20: A Glance at Structure‐Property Relationship
Published in Small (Weinheim an der Bergstrasse, Germany) (06-12-2023)“…Doping Cd atom(s) into gold clusters is very promising in both theoretical study and practical applications. However, it has long been a challenge to…”
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Efficient synthesis of primary and secondary amides via reacting esters with alkali metal amidoboranes
Published in Nature communications (13-10-2021)“…Amides are one of the most important organic compounds that are widely applied in medicine, biochemistry, and materials science. To find an efficient synthetic…”
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New insights into the effects of APP gene dose on synapse in Down syndrome
Published in Neural regeneration research (01-05-2024)Get full text
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Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome
Published in Free radical biology & medicine (01-01-2018)“…Neurotrophic factors, including the members of the neurotrophin family, play important roles in the development and maintenance of the nervous system. Trophic…”
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