Search Results - "Xu, Pingxiang"
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Phencynonate S-isomer as a eutomer is a novel central anticholinergic drug for anti-motion sickness
Published in Scientific reports (13-02-2019)“…To compare and evaluate the differences of stereoselective activity, the binding affinity, metabolism, transport and molecular docking of phencynonate isomers…”
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2
Can Carbon Emission Regulation Achieve a Dual Target of Low Carbon and Employment? An Empirical Analysis Based on China’s Provincial Panel Data
Published in Frontiers in energy research (19-07-2022)“…The Phillips curve of environment (EPC) and the environmental Kuznets curve of employment (EKCE) both indicate that the low-carbon economic transition can…”
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3
Multiple-Omics Techniques Reveal the Role of Glycerophospholipid Metabolic Pathway in the Response of Saccharomyces cerevisiae Against Hypoxic Stress
Published in Frontiers in microbiology (27-06-2019)“…Although the biological processes of organism under hypoxic stress had been elucidated, the whole physiological changes of are still unclear. In this work, we…”
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4
The COVID-19 shock and the ownership of store Chain:Evidence from China's express delivery industry
Published in Heliyon (01-10-2023)“…Utilizing stock market data of express delivery companies that have been listed on the stock market of China, this paper intends to examine the two alternative…”
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Multi-omics analysis reveals phenylalanine enhance mitochondrial function and hypoxic endurance via LKB1/AMPK activation
Published in Journal of translational medicine (10-10-2024)“…Many studies have focused on the effects of small molecules, such as amino acids, on metabolism under hypoxia. Recent findings have indicated that…”
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A UPLC-MS/MS method reveals the pharmacokinetics and metabolism characteristics of kaempferol in rats under hypoxia
Published in Drug metabolism and pharmacokinetics (01-04-2022)“…As a natural flavonoid, kaempferol is widely distributed in natural medicines. Our study was aimed at analyzing and comparing the pharmacokinetic differences…”
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Long-Circulating and Brain-Targeted Liposomes Loaded with Isoliquiritigenin: Formation, Characterization, Pharmacokinetics, and Distribution
Published in Pharmaceutics (24-07-2024)“…Isoliquiritigenin (ISL) has excellent neuroprotective effects. However, its limitations, including poor solubility, low bioavailability, and low accumulation…”
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Daidzein is the in vivo active compound of Puerariae Lobatae Radix water extract for muscarinic receptor-3 inhibition against overactive bladder
Published in Frontiers in pharmacology (04-10-2022)“…Background: In the previous study, Puerariae Lobatae Radix (named Gegen in Chinese) water extract attenuated M3 receptor agonist carbachol-induced detrusor…”
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Simultaneous Quantification of Diazepam and Dexamethasone in Plasma by High-Performance Liquid Chromatography with Tandem Mass Spectrometry and Its Application to a Pharmacokinetic Comparison between Normoxic and Hypoxic Rats
Published in Molecules (Basel, Switzerland) (16-04-2015)“…In order to investigate the pharmacokinetics of a combination of diazepam and dexamethasone under hypoxic conditions, a novel, sensitive and specific liquid…”
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A Dataset for Constructing the Network Pharmacology of Overactive Bladder and Its Application to Reveal the Potential Therapeutic Targets of Rhynchophylline
Published in Pharmaceuticals (Basel, Switzerland) (24-09-2024)“…: Network pharmacology is essential for understanding the multi-target and multi-pathway therapeutic mechanisms of traditional Chinese medicine. This study…”
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11
Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
Published in International journal of nanomedicine (01-01-2014)“…A green, one-step microwave-assisted polyol synthesis was employed to prepare blue luminescent carbon nitride dots (CNDs) using folic acid molecules as both…”
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12
Receptor and transporter binding and activity profiles of albiflorin extracted from Radix paeoniae Alba
Published in Scientific reports (20-09-2016)“…Albiflorin, a traditional Chinese herb, is a main component of Radix paeoniae Alba , which has been used for the treatment of depressive disorders since…”
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13
Glucuronidation is the dominating in vivo metabolism pathway of herbacetin: Elucidation of herbacetin pharmacokinetics after intravenous and oral administration in rats
Published in Journal of functional foods (01-01-2018)“…The promising potential benefits of herbacetin in human entail its pharmacokinetic investigations, but the metabolic fate of this natural compound in vivo…”
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14
Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, a marine algae derived bromophenol, inhibits the growth of Botrytis cinerea and interacts with DNA molecules
Published in Marine drugs (27-06-2014)“…Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE) is a bromophenol isolated from marine algae. Previous reports have shown that BDDE possesses cytotoxic and…”
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15
Anti-Hypoxic Molecular Mechanisms of Rhodiola crenulata Extract in Zebrafish as Revealed by Metabonomics
Published in Frontiers in pharmacology (12-11-2019)“…The health supplement of Rhodiola crenulata ( RC ) is well known for its effective properties against hypoxia. However, the mechanisms of its anti-hypoxic…”
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Enhancement of Exposure and Reduction of Elimination for Paeoniflorin or Albiflorin via Co-Administration with Total Peony Glucosides and Hypoxic Pharmacokinetics Comparison
Published in Molecules (Basel, Switzerland) (01-07-2016)“…There is evidence suggesting that herbal extracts demonstrate greater bioactivities than their isolated constituents at an equivalent dose. This phenomenon…”
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17
Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II
Published in Journal of experimental & clinical cancer research (16-11-2016)“…Lapachol is a natural naphthoquinone compound that possesses extensive biological activities. The aim of this study is to investigate the inhibitory effects of…”
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18
Regulatory effect of connexin 43 on basal Ca2+ signaling in rat ventricular myocytes
Published in PloS one (27-04-2012)“…It has been found that gap junction-associated intracellular Ca(2+) [Ca(2+)](i) disturbance contributes to the arrhythmogenesis and hyperconstriction in…”
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Sub-Acute Oral Toxicity of a Novel Derivative of Agomelatine in Rats in a Sex-Dependent Manner
Published in Frontiers in pharmacology (19-03-2019)“…Agomelatine (AGO) is a new type of antidepressant with demonstrated antidepressant effects and a unique modulating circadian rhythm action. However, AGO has…”
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Role of Inositol-1,4,5-Trisphosphate Receptor in the Regulation of Calcium Transients in Neonatal Rat Ventricular Myocytes
Published in Journal of Pharmacological Sciences (2014)“…This study determined the regulatory effect of inositol 1,4,5-trisphosphate receptors (IP3Rs) on the basal Ca2+ transients in cardiomyocytes. In cultured…”
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