Search Results - "Xu, Peining"

Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses by Langston, P. Kent, Nambu, Aya, Jung, Jonathan, Shibata, Munehiko, Aksoylar, H. Ibrahim, Lei, Jiahui, Xu, Peining, Doan, Mary T., Jiang, Helen, MacArthur, Michael R., Gao, Xia, Kong, Yong, Chouchani, Edward T., Locasale, Jason W., Snyder, Nathaniel W., Horng, Tiffany

“…Macrophages are activated during microbial infection to coordinate inflammatory responses and host defense. Here we find that in macrophages activated by…”
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Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich’s ataxia by Wang, Dezhen, Ho, Elaine S., Cotticelli, M. Grazia, Xu, Peining, Napierala, Jill S., Hauser, Lauren A., Napierala, Marek, Himes, Blanca E., Wilson, Robert B., Lynch, David R., Mesaros, Clementina

“…Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by a triplet guanine-adenine-adenine (GAA) repeat expansion in intron 1…”
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PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies by Chen, Saisai, Paul, Matt R, Sterner, Christopher J, Belka, George K, Wang, Dezhen, Xu, Peining, Sreekumar, Amulya, Pan, Tien-Chi, Pant, Dhruv K, Makhlin, Igor, DeMichele, Angela, Mesaros, Clementina, Chodosh, Lewis A

“…Breast cancer mortality is principally due to recurrent disease that becomes resistant to therapy. We recently identified copy number (CN) gain of the putative…”
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Preliminary results of identification and quantification of paclitaxel and its metabolites in human meconium from newborns with gestational chemotherapeutic exposure by Cardonick, Elyce, Broadrup, Robert, Xu, Peining, Doan, Mary T, Jiang, Helen, Snyder, Nathaniel W

“…Cancer diagnosis during pregnancy occurs in 1 out of 1000 pregnancies with common malignancies including breast and hematological cancers. Fetal exposure to…”
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Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species by Doan, Mary T., Neinast, Michael D., Varner, Erika L., Bedi, Kenneth C., Bartee, David, Jiang, Helen, Trefely, Sophie, Xu, Peining, Singh, Jay P., Jang, Cholsoon, Rame, J. Eduardo, Brady, Donita C., Meier, Jordan L., Marguiles, Kenneth B., Arany, Zoltan, Snyder, Nathaniel W.

“…Anabolic metabolism of carbon in mammals is mediated via the one- and two-carbon carriers S-adenosyl methionine and acetyl-coenzyme A. In contrast, anabolic…”
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Author Correction: Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses by Langston, P. Kent, Nambu, Aya, Jung, Jonathan, Shibata, Munehiko, Aksoylar, H. Ibrahim, Lei, Jiahui, Xu, Peining, Doan, Mary T., Jiang, Helen, MacArthur, Michael R., Gao, Xia, Kong, Yong, Chouchani, Edward T., Locasale, Jason W., Snyder, Nathaniel W., Horng, Tiffany

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism by Trefely, Sophie, Liu, Joyce, Huber, Katharina, Doan, Mary T., Jiang, Helen, Singh, Jay, von Krusenstiern, Eliana, Bostwick, Anna, Xu, Peining, Bogner-Strauss, Juliane G., Wellen, Kathryn E., Snyder, Nathaniel W.

“…The dynamic regulation of metabolic pathways can be monitored by stable isotope tracing. Yet, many metabolites are part of distinct processes within different…”
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Comprehensive and robust analysis of the whole blood sphingolipidome by LC‐HRMS by Wang, Dezhen, Xu, Peining, Mesaros, Clementina

“…Plasma and serum are the most widely used blood‐derived biofluids for metabolomics and lipidomics assays, but many analytes that are present at high…”
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Analytical considerations for reducing the matrix effect for the sphingolipidome quantification in whole blood by Wang, Dezhen, Xu, Peining, Mesaros, Clementina

“…Plasma and serum are widely used blood-derived biofluids for metabolomics and lipidomics assays, but analytes that are present in high concentrations in blood…”
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Ultrasensitive quantification of estrogens in serum and plasma by liquid chromatography-tandem mass spectrometry by Wang, Qingqing, Xu, Peining Jimmy, Mesaros, Clementina

“…Stable isotope dilution (SID) methodology coupled with liquid chromatography-tandem mass spectrometry (LC-MS) is rapidly becoming the gold standard for…”
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Follow Up of Newborns Exposed to Paclitaxel in Utero Evident by Metabolites in First Meconium Sample [28H] by Cardonick, Elyce, Akoto, Serwaa, Doan, Mary, Xu, Peining J., Snyder, Nathaniel, Broadrup, Robert

“…INTRODUCTION: Paclitaxel is excluded from breast cancer treatment during pregnancy due to limited neonatal follow up. We confirmed fetal paclitaxel exposure by…”
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Association Between Midpregnancy Polyunsaturated Fatty Acid Levels and Offspring Autism Spectrum Disorder in a California Population-Based Case-Control Study by Lyall, Kristen, Windham, Gayle C, Snyder, Nathaniel W, Kuskovsky, Rostislav, Xu, Peining, Bostwick, Anna, Robinson, Lucy, Newschaffer, Craig J

“…Abstract Polyunsaturated fatty acids (PUFAs) are critical for brain development and have been linked with neurodevelopmental outcomes. We conducted a…”
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Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich’s ataxia by Weng, Liwei, Laboureur, Laurent, Wang, Qingqing, Guo, Lili, Xu, Peining, Gottlieb, Leah, Lynch, David R., Mesaros, Clementina, Blair, Ian A.

“…Mature frataxin is essential for the assembly of iron–sulfur cluster proteins including a number of mitochondrial enzymes. Reduced levels of mature frataxin…”
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Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry by Kuskovsky, Rostislav, Buj, Raquel, Xu, Peining, Hofbauer, Samuel, Doan, Mary T., Jiang, Helen, Bostwick, Anna, Mesaros, Clementina, Aird, Katherine M., Snyder, Nathaniel W.

“…Quantification of cellular deoxyribonucleoside mono- (dNMP), di- (dNDP), triphosphates (dNTPs) and related nucleoside metabolites are difficult due to their…”
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Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreich's Ataxia by Napierala, Jill S., Rajapakshe, Kimal, Clark, Amanda, Chen, Yu-Yun, Huang, Shixia, Mesaros, Clementina, Xu, Peining, Blair, Ian A., Hauser, Lauren A., Farmer, Jennifer, Lynch, David R., Edwards, Dean P., Coarfa, Cristian, Napierala, Marek

“…Identifying biomarkers is important for assessment of disease progression, prediction of symptom development, and determination of treatment effectiveness…”
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Artefactual formation of pyruvate from in-source conversion of lactate by Trefely, Sophie, Mesaros, Clementina, Xu, Pening, Doan, Mary T, Jiang, Helen, Altinok, Oya, Orynbayeva, Zulfiya, Snyder, Nathaniel W

“…Lactate and pyruvate are high abundance products of glucose metabolism. Analysis of both molecules as part of metabolomics studies in cellular metabolism and…”
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Cumulus cell acetyl-CoA metabolism from acetate is associated with maternal age but inconclusively with oocyte maturity by Anderson, Sharon, Xu, Peining, Frey, Alexander J., Goodspeed, Jason R., Doan, Mary T., Orris, John J., Clements, Nicolle, Glassner, Michael J., Snyder, Nathaniel W.

“…Cumulus cell (CC) clumps that associate with oocytes provide the oocytes with growth and signaling factors. Thus, the metabolism of the CCs may influence…”
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Altered lipid homeostasis is associated with cerebellar neurodegeneration in SNX14 deficiency by Zhou, Yijing, Sanchez, Vanessa B, Xu, Peining, Roule, Thomas, Flores-Mendez, Marco, Ciesielski, Brianna, Yoo, Donna, Teshome, Hiab, Jimenez, Teresa, Liu, Shibo, Henne, Mike, O'Brien, Tim, He, Ye, Mesaros, Clementina, Akizu, Naiara

“…Dysregulated lipid homeostasis is emerging as a potential cause of neurodegenerative disorders. However, evidence of errors in lipid homeostasis as a…”
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Discovery and Mechanism of Action of a Novel HIV-1 Capsid Inhibitor, CX06 by Xu, Peining

“…Human immunodeficiency virus type 1 (HIV-1) is the etiologic agent responsible for the acquired immunodeficiency syndrome (AIDS) pandemic worldwide. Current…”
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Cumulus cell acetyl-CoA metabolism from acetate is associated with maternal age but only partially with oocyte maturity by Anderson, Sharon, Xu, Peining, Frey, Alexander J, Goodspeed, Jason R, Doan, Mary T, Orris, John J, Clements, Nicolle, Glassner, Michael J, Snyder, Nathaniel W

“…Cumulus cell (CC) clumps that associate with oocytes provide the oocytes with growth and signaling factors. Thus, the metabolism of the CCs may influence…”
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