Search Results - "Xu, Linping"
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Regulation of PD-L1 expression in the tumor microenvironment
Published in Journal of hematology and oncology (07-01-2021)“…Programmed death-ligand 1 (PD-L1) on cancer cells engages with programmed cell death-1 (PD-1) on immune cells, contributing to cancer immune escape. For…”
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Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4
Published in Molecular cancer (06-11-2019)“…The emergence of immune checkpoint inhibitors (ICIs), mainly including anti-programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) and…”
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3
The role of cancer-derived microRNAs in cancer immune escape
Published in Journal of hematology and oncology (28-03-2020)“…During malignant transformation, accumulated somatic mutations endow cancer cells with increased invasiveness and immunogenicity. Under selective pressure,…”
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SIRPα and PD1 expression on tumor-associated macrophage predict prognosis of intrahepatic cholangiocarcinoma
Published in Journal of translational medicine (22-03-2022)“…The phagocytosis checkpoints of CD47/SIRPα, PD1/PDL1, CD24/SIGLEC10, and MHC/LILRB1 have shown inhibited phagocytosis of macrophages in distinct tumors…”
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Targeting macrophages: a novel treatment strategy in solid tumors
Published in Journal of translational medicine (12-12-2022)“…In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most abundant immune cells, which act as a key regulator in tumorigenesis and…”
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Chimeric antigen receptor-immune cells against solid tumors: Structures, mechanisms, recent advances, and future developments
Published in Chinese medical journal (05-06-2024)“…The advent of chimeric antigen receptor (CAR)-T cell immunotherapies has led to breakthroughs in the treatment of hematological malignancies. However, their…”
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Alcohol Consumption by Beverage Type and Risk of Breast Cancer: A Dose-Response Meta-Analysis of Prospective Cohort Studies
Published in Alcohol and alcoholism (Oxford) (16-04-2020)“…Abstract Aims Alcohol intake has been shown to increase the risk of breast cancer. However, the dose-response analysis of different alcoholic beverages…”
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Monodisperse Sn Nanocrystals as a Platform for the Study of Mechanical Damage during Electrochemical Reactions with Li
Published in Nano letters (10-04-2013)“…Monodisperse Sn spherical nanocrystals of 10.0 ± 0.2 nm were prepared in dispersible colloidal form. They were used as a model platform to study the impact of…”
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Upregulation of LINC01426 promotes the progression and stemness in lung adenocarcinoma by enhancing the level of SHH protein to activate the hedgehog pathway
Published in Cell death & disease (10-02-2021)“…Long noncoding RNAs (lncRNAs) play crucial roles in regulating a variety of biological processes in lung adenocarcinoma (LUAD). In our study, we mainly…”
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Structural Distortion of Molybdenum-Doped Manganese Oxide Octahedral Molecular Sieves for Enhanced Catalytic Performance
Published in Inorganic chemistry (02-11-2015)“…Due to the excellent catalytic performance of manganese oxide (K-OMS-2) in a wide range of applications, incorporation of various dopants has been commonly…”
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Identification of macrophage correlated biomarkers to predict the prognosis in patients with intrahepatic cholangiocarcinoma
Published in Frontiers in oncology (08-09-2022)“…Background It has been shown that tumor-associated immune cells, particularly macrophages, play a fundamental role in the development and treatment response of…”
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CXCL1 as an Unfavorable Prognosis Factor Negatively Regulated by DACH1 in Non-small Cell Lung Cancer
Published in Frontiers in oncology (10-01-2020)“…Interaction between cancer cells with microenvironment is essential for cancer progression, therapeutic resistance and prognosis. Chemokine CXCL1 shows…”
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Exploiting the potential of the ubiquitin-proteasome system in overcoming tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Published in Genes & diseases (01-09-2024)“…The advent of tyrosine kinase inhibitors (TKI) targeting BCR-ABL has drastically changed the treatment approach of chronic myeloid leukemia (CML), greatly…”
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A comprehensive pan-cancer analysis revealing the role of ITPRIPL1 as a prognostic and immunological biomarker
Published in Frontiers in molecular biosciences (15-08-2024)“…Inositol 1,4,5-Trisphosphate Receptor-Interacting Protein-Like 1 (ITPRIPL1), a single-pass type I membrane protein located in the membrane, functions as an…”
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Variant in BCAR4 gene correlated with the breast cancer susceptibility and mRNA expression of lncRNA BCAR4 in Chinese Han population
Published in Breast cancer (Tokyo, Japan) (01-03-2021)“…Background Long non-coding RNA (LncRNA) Breast cancer anti-estrogen resistance 4 ( BCAR4 ) has been shown to participate in the biological progress of various…”
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Identification of potential resistance mechanisms and therapeutic targets for the relapse of BCMA CAR-T therapy in relapsed/refractory multiple myeloma through single-cell sequencing
Published in Experimental hematology & oncology (08-05-2023)“…BCMA CAR-T is highly effective for relapsed/refractory multiple myeloma(R/R-MM) and significantly improves the survival of patients. However, the short…”
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17
Syntheses of Nanostructures of Cobalt Hydrotalcite Like Compounds and Co3O4 via a Microwave-Assisted Reflux Method
Published in Journal of physical chemistry. C (05-06-2008)“…An efficient microwave-assisted reflux route has been used to synthesize layered nanostructures of cobalt hydrotalcite like compound spheres. Scanning electron…”
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Characterization of lncRNA LINC00520 and functional polymorphisms associated with breast cancer susceptibility in Chinese Han population
Published in Cancer medicine (Malden, MA) (01-03-2020)“…Background The aim was to evaluate the association between the LINC00520 genetic polymorphisms and breast cancer (BC) susceptibility. Methods Nine…”
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ZnO/La2O2CO3 layered composite: A new heterogeneous catalyst for the efficient ultra-fast microwave biofuel production
Published in Applied catalysis. B, Environmental (14-03-2011)“…[Display omitted] ▶ First example of low temperature active heterogeneous catalysts for environmentally friendly biodiesel production without a leaching…”
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Efficacy of Tumor-Infiltrating Lymphocytes Combined with IFN-α in Chinese Resected Stage III Malignant Melanoma
Published in Journal of immunology research (01-01-2017)“…Background. This study aims to explore the efficacy of tumor-infiltrating lymphocytes (TIL) along with interferon-α (IFN-α) to treat stage III malignant…”
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