Search Results - "Xu, Leiqi"

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity by Yang, Wenjing, Yu, Tianming, Huang, Xiangsheng, Bilotta, Anthony J., Xu, Leiqi, Lu, Yao, Sun, Jiaren, Pan, Fan, Zhou, Jia, Zhang, Wenbo, Yao, Suxia, Maynard, Craig L., Singh, Nagendra, Dann, Sara M., Liu, Zhanju, Cong, Yingzi

“…Innate lymphoid cells (ILCs) and CD4 + T cells produce IL-22, which is critical for intestinal immunity. The microbiota is central to IL-22 production in the…”
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Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway by Yang, Huimin, Xie, Tingting, Li, Dengren, Du, Xianhong, Wang, Tixiao, Li, Chunyang, Song, Xiaojia, Xu, Leiqi, Yi, Fan, Liang, Xiaohong, Gao, Lifen, Yang, Xiangdong, Ma, Chunhong

“…Macrophage-mediated inflammation plays a significant role in the development and progression of diabetic nephropathy (DN). However, the underlying mechanisms…”
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Microbiota Metabolite Short-Chain Fatty Acids Facilitate Mucosal Adjuvant Activity of Cholera Toxin through GPR43 by Yang, Wenjing, Xiao, Yi, Huang, Xiangsheng, Chen, Feidi, Sun, Mingming, Bilotta, Anthony J, Xu, Leiqi, Lu, Yao, Yao, Suxia, Zhao, Qihong, Liu, Zhanju, Cong, Yingzi

“…The gut microbiota has been shown critical for mucosal adjuvant activity of cholera toxin (CT), a potent mucosal adjuvant. However, the mechanisms involved…”
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Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis by Liu, Chang, Xia, Yanan, Fu, Shichen, Meng, Fanyi, Feng, Bingcheng, Xu, Leiqi, Li, Lixiang, Zuo, Xiuli

“…Abstract Piezo1, the mechanosensory ion channel, has attracted increasing attention for its essential roles in various inflammatory responses and…”
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Tumor suppressor ZHX2 restricts hepatitis B virus replication via epigenetic and non-epigenetic manners by Xu, Leiqi, Wu, Zhuanchang, Tan, Siyu, Wang, Zehua, Lin, Qinghai, Li, Xiaoyan, Song, Xiaojia, Liu, Yuan, Song, Yang, Zhang, Jie, Peng, Jun, Gao, Lifen, Gong, Yaoqin, Liang, Xiaohong, Zuo, Xiuli, Ma, Chunhong

“…Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA), the stable genomic form as the template for viral transcription, plays a crucial role in viral…”
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ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation by Lin, Qinghai, Wu, Zhuanchang, Yue, Xuetian, Yu, Xiangguo, Wang, Zehua, Song, Xiaojia, Xu, Leiqi, He, Ying, Ge, Yutong, Tan, Siyu, Wang, Tixiao, Song, Hui, Yuan, Detian, Gong, Yaoqin, Gao, Lifen, Liang, Xiaohong, Ma, Chunhong

“…Liver cancer stem cells (CSCs) are critical determinants of HCC relapse and therapeutic resistance, but the mechanisms underlying the maintenance of CSCs are…”
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Sex-related Differences in Inflammatory Bowel Diseases: The Potential Role of Sex Hormones by Xu, Leiqi, Huang, Gang, Cong, Yingzi, Yu, Yanbo, Li, Yanqing

“…Abstract Inflammatory bowel disease (IBD), characterized by chronic inflammation of the gastrointestinal tract, is a global health care problem. Compelling…”
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Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis by Chen, Liang, Sun, Mingming, Wu, Wei, Yang, Wenjing, Huang, Xiangsheng, Xiao, Yi, Ma, Chunyan, Xu, Leiqi, Yao, Suxia, Liu, Zhanju, Cong, Yingzi

“…How the gut microbiota regulates intestinal homeostasis is not completely clear. Gut microbiota metabolite short-chain fatty acids (SCFAs) have been reported…”
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Health information in short videos about metabolic dysfunction‐associated steatotic liver disease: Analysing quality and reliability by Ding, Ruihao, Kong, Qingzhou, Sun, Longfei, Liu, Xuyan, Xu, Leiqi, Li, Yueyue, Zuo, Xiuli, Li, Yanqing

“…Background & Aims Short videos, crucial for disseminating health information on metabolic dysfunction‐associated steatotic liver disease (MASLD), lack a clear…”
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GPR120 Inhibits Colitis Through Regulation of CD4+ T Cell Interleukin 10 Production by Yang, Wenjing, Liu, Han, Xu, Leiqi, Yu, Tianming, Zhao, Xiaojing, Yao, Suxia, Zhao, Qihong, Barnes, Sean, Cohn, Steven M., Dann, Sara M., Zhang, Hongjie, Zuo, Xiuli, Li, Yanqing, Cong, Yingzi

“…G protein–coupled receptor (GPR) 120 has been implicated in regulating metabolic syndromes with anti-inflammatory function. However, the role of GPR120 in…”
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Clarifying varied Helicobacter pylori eradication therapies: A comprehensive review by Wu, Xiaoqi, Duan, Miao, Kong, Qingzhou, Zeng, Shuyan, Xu, Leiqi, Li, Yueyue, Yang, Xiaoyun, Zuo, Xiuli

“…Current global variations exist in Helicobacter pylori (H. pylori) eradication regimens. Triple therapy (TT), bismuth quadruple therapy (BQT), and high-dose…”
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MicroRNA-10a Negatively Regulates CD4+ T Cell IL-10 Production through Suppression of Blimp1 by Yang, Wenjing, Chen, Liang, Xu, Leiqi, Bilotta, Anthony J., Yao, Suxia, Liu, Zhanju, Cong, Yingzi

“…Abstract An uncontrolled CD4+ T cell response is a critical hallmark of autoimmune diseases. IL-10, which can be produced by both effector and regulatory CD4+…”
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HBV suppresses ZHX2 expression to promote proliferation of HCC through miR‐155 activation by Song, Xiaojia, Tan, Siyu, Wu, Zhuanchang, Xu, Leiqi, Wang, Zehua, Xu, Yong, Wang, Tixiao, Gao, Chengjiang, Gong, Yaoqin, Liang, Xiaohong, Gao, Lifen, Spear, Brett T., Ma, Chunhong

“…Initiation of hepatocellular carcinoma (HCC) by chronic hepatitis B virus (HBV) infection is a complex process that includes both oncogene activation and tumor…”
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TikTok and Bilibili as health information sources on gastroesophageal reflux disease: an assessment of content and its quality by Liu, Xuyan, Kong, Qingzhou, Song, Yihao, Ding, Ruihao, Sun, Longfei, Xu, Leiqi, Li, Yueyue, Zuo, Xiuli, Li, Yanqing

“…Gastroesophageal reflux disease (GERD) is a global chronic disease. Short video platforms make it easy for patients with GERD to obtain medical information…”
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NgAgo-gDNA system efficiently suppresses hepatitis B virus replication through accelerating decay of pregenomic RNA by Wu, Zhuanchang, Tan, Siyu, Xu, Leiqi, Gao, Lifen, Zhu, Haizhen, Ma, Chunhong, Liang, Xiaohong

“…Covalently closed circular DNA (cccDNA) in the hepatocytes nucleus is responsible for persistent infection of Hepatitis B virus (HBV). Current antiviral…”
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Artificial Intelligence‐Generated Patient Education Materials for Helicobacter pylori Infection: A Comparative Analysis by Zeng, Shuyan, Kong, Qingzhou, Wu, Xiaoqi, Ma, Tian, Wang, Limei, Xu, Leiqi, Kou, Guanjun, Zhang, Mingming, Yang, Xiaoyun, Zuo, Xiuli, Li, Yueyue, Li, Yanqing

“…ABSTRACT Background Patient education contributes to improve public awareness of Helicobacter pylori. Large language models (LLMs) offer opportunities to…”
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ZHX2 inhibits SREBP1c‐mediated de novo lipogenesis in hepatocellular carcinoma via miR‐24‐3p by Yu, Xiangguo, Lin, Qinghai, Wu, Zhuanchang, Zhang, Yankun, Wang, Tixiao, Zhao, Songbai, Song, Xiaojia, Chen, Chaojia, Wang, Zehua, Xu, Leiqi, Li, Chunyang, Gao, Lifen, Liang, Xiaohong, Yue, Xuetian, Ma, Chunhong

“…Hepatocellular carcinoma (HCC) is one of the leading causes of cancer‐related death worldwide. Lipogenesis has been considered as a critical player in HCC…”
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GPR120 inhibits colitis through regulation of CD4+T cell IL-10 production by Yang, Wenjing, Liu, Han, Xu, Leiqi, Yu, Tianming, Zhao, Xiaojing, Yao, Suxia, Zhao, Qihong, Barnes, Sean, Cohn, Steven M., Dann, Sara M., Zhang, Hongjie, Zuo, Xiuli, Li, Yanqing, Cong, Yingzi

“…Long-chain fatty acid receptor G protein-coupled receptor 120 induces interleukin-10 production in CD4 + T cells to inhibit colitis development through…”
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Hepatitis B virus X protein amplifies TGF-β promotion on HCC motility through down-regulating PPM1a by Liu, Yuan, Xu, Yong, Ma, Hongxin, Wang, Bo, Xu, Leiqi, Zhang, Hualin, Song, Xiaojia, Gao, Lifen, Liang, Xiaohong, Ma, Chunhong

“…Over-activation of transforming growth factor-β (TGF-β) signaling pathway promotes cell migration and invasion in hepatocellular carcinoma (HCC). The Hepatitis…”
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MicroRNA-10a regulates intestinal mucosal dendritic cell development and function by targeting CD11c by Huang, Xiangsheng, Chen, Feidi, Xue, Xiaochang, Chen, Liang, Yang, Wenjing, Xu, Leiqi, Bilotta, Anthony James, Yao, Suxia, Cong, Yingzi

“…Abstract We have previously demonstrated that microRNA-10a (miR-10a), highly expressed in intestine DC and epithelial cells, and negatively regulated by…”
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