Search Results - "Xu, Keshu"

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  1. 1

    Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages by Liu, Beibei, Deng, Xiaoling, Jiang, Qianqian, Li, Guixin, Zhang, Junli, Zhang, Ning, Xin, Shengliang, Xu, Keshu

    Published in Biomedicine & pharmacotherapy (01-05-2020)
    “…•Scoparone improves hepatic inflammation and autophagy in mice with MCD diet.•Scoparone has an effect on autophag in macrophages, but not…”
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  2. 2

    Resolvin D1 attenuates CCl4 Induced Liver Fibrosis by Inhibiting Autophagy-Mediated HSC activation via AKT/mTOR Pathway by Li, Jiahuan, Deng, Xiaoling, Wang, Shuhan, Jiang, Qianqian, Xu, Keshu

    Published in Frontiers in pharmacology (20-12-2021)
    “…Resolvin D1 (RvD1) was previously reported to relieve inflammation and liver damage in several liver diseases, but its potential role in liver fibrosis remains…”
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  3. 3

    The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease by Junli, Zhang, Shuhan, Wang, Yajuan, Zhao, Xiaoling, Deng, Jiahuan, Li, Keshu, Xu

    Published in Life sciences (1973) (01-10-2022)
    “…To investigate the effect of cAMP response element-binding protein H (CREBH) on metabolic associated fatty liver disease by regulating sirtuin 3 (SIRT3). Two…”
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  4. 4

    Identification and Validation of a Nine-Gene Amino Acid Metabolism-Related Risk Signature in HCC by Zhao, Yajuan, Zhang, Junli, Wang, Shuhan, Jiang, Qianqian, Xu, Keshu

    “…Background: Hepatocellular carcinoma (HCC) is the world’s second most deadly cancer, and metabolic reprogramming is its distinguishing feature. Among…”
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  5. 5

    CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease by Li, Guixin, Zhang, Junli, Jiang, Qianqian, Liu, Beibei, Xu, Keshu

    Published in Life sciences (1973) (01-08-2020)
    “…The primary focus of this study was to explore the effects of cyclic AMP response element-binding protein H (CREBH) on the development of nonalcoholic fatty…”
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  6. 6

    Gadoxetic Acid-Enhanced Hepatobiliary-Phase Magnetic Resonance Imaging for Pyrrolizidine Alkaloid-Induced Hepatic Sinusoidal Obstruction Syndrome and Association with Liver Function by Guo, Tingting, Li, Xin, Yang, Xiaoqian, Kong, Xiangquan, Liu, Hui, Bai, Tao, Xu, Keshu, Ye, Jin, Song, Yuhu

    Published in Scientific reports (04-02-2019)
    “…Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by pyrrolizidine alkaloids(PAs)-containing herbals. In this study, the aim of our study was to…”
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  7. 7

    Prevalence and impact of Sjögren's syndrome in primary biliary cholangitis: a systematic review and meta-analysis by Deng, Xiaoling, Li, Jiahuan, Hou, Shuhui, Ci, Bai, Liu, Beibei, Xu, Keshu

    Published in Annals of hepatology (01-11-2022)
    “…We performed a systematic review and meta-analysis to evaluate the prevalence of concomitant Sjögren's syndrome (SS) with primary biliary cholangitis (PBC) in…”
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  8. 8

    p-CREB-1 promotes hepatic fibrosis through the transactivation of transforming growth factor-β1 expression in rats by Wang, Pei, Deng, Liang, Zhuang, Chunbo, Cheng, Chunwei, Xu, Keshu

    “…Phosphorylated cAMP-responsive element binding protein-1 (p-CREB-1) is an important transcription factor which has been reported to be implicated in…”
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  9. 9

    Evaluation of tumor markers for the differential diagnosis of benign and malignant ascites by Liu, Fang, Kong, Xinjuan, Dou, Qian, Ye, J.i.n, Xu, Dong, Shang, Haitao, Xu, Keshu, Song, Yuhu, M.D., Ph.D

    Published in Annals of hepatology (01-05-2014)
    “…AbstractIntroduction. The diagnosis of malignant ascites is a challenging problem in clinical practice, non-invasive techniques should be developed to improve…”
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  10. 10

    rAAV2-TGF-β3 Decreases Collagen Synthesis and Deposition in the Liver of Experimental Hepatic Fibrosis Rat by Zhang, Yi, Liu, Ping, Gao, Xiaoliang, Qian, Wei, Xu, Keshu

    Published in Digestive diseases and sciences (01-10-2010)
    “…Background/Aims Hepatic fibrosis is one kind of common wound-healing response to chronic liver injury. Transforming growth factor (TGF)-β 3 performs an…”
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  11. 11

    Zhikang Capsule ameliorates dextran sodium sulfate-induced colitis by inhibition of inflammation, apoptosis, oxidative stress and MyD88-dependent TLR4 signaling pathway by Fei, Liang, Xu, Keshu

    Published in Journal of ethnopharmacology (04-11-2016)
    “…Zhikang Capsule (ZKC) is a traditional Chinese medicine (TCM) modified from classic formulas Qi-Li-San (an ancient formula dating to Qing Dynasty) and…”
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  12. 12

    Improvement of the diffraction properties in holographic polymer dispersed liquid crystal bragg gratings by Liu, YanJun, Zhang, Bin, Jia, Yu, Xu, KeShu

    Published in Optics communications (15-03-2003)
    “…Holographic polymer dispersed liquid crystal (HPDLC) is a new kind of holographic material. It can be fabricated by the photo-initiated polymerization-induced…”
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  13. 13

    CREB family: A significant role in liver fibrosis by Li, Guixin, Jiang, Qianqian, Xu, Keshu

    Published in Biochimie (01-08-2019)
    “…Liver fibrosis (LF) is known as a result of the progressive accumulation of extracellular matrix (ECM), and always ascribed to chronic liver diseases. Advanced…”
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  14. 14
  15. 15

    Advances in characterization of SIRT3 deacetylation targets in mitochondrial function by Wang, Shuhan, Zhang, Junli, Deng, Xiaoling, Zhao, Yajuan, Xu, Keshu

    Published in Biochimie (01-12-2020)
    “…The homeostasis of mitochondrial functional state is intimately in relation with SIRT3 (sirtuin3). SIRT3, the deacetylase mainly anchored in mitochondria, acts…”
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  16. 16

    CREBH alleviates mitochondrial oxidative stress through SIRT3 mediating deacetylation of MnSOD and suppression of Nlrp3 inflammasome in NASH by Zhang, Junli, Zhao, Yajuan, Wang, Shuhan, Li, Guixin, Xu, Keshu

    Published in Free radical biology & medicine (01-09-2022)
    “…Lipotoxicity and unresolved oxidative stress are key drivers of metabolic inflammation in nonalcoholic steatohepatitis (NASH). cAMP-response element binding…”
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  17. 17

    Characteristics of LCoS Phase-only spatial light modulator and its applications by Dai, HaiTao, Liu, KeShu Xu YanJun, Wang, Xin, Liu, Jianhua

    Published in Optics communications (15-08-2004)
    “…The working models of LCoS (Liquid Crystal on Silicon) were optimized in parameter space by simulation. Two modes were selected, which were suitable for phase…”
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  18. 18

    Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice by Zhang, Junli, Zhang, Haiming, Deng, Xiaoling, Zhang, Ning, Liu, Beibei, Xin, Shengliang, Li, Guixin, Xu, Keshu

    Published in Life sciences (1973) (01-01-2018)
    “…Baicalin (BA), an active flavonoid compound originating from the herb of Scutellaria baicalensis Georgi, has been previously shown to exert anti-inflammation…”
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  19. 19

    Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation by Zhang, Junli, Zhang, Haiming, Deng, Xiaoling, Zhang, Yuping, Xu, Keshu

    Published in Chemico-biological interactions (25-12-2017)
    “…Baicalin (BA) is an active flavonoid compound originating from the root of Scutellaria baicalensis Georgi that has been reported to exert anti-inflammation and…”
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  20. 20

    Increased expression of sterol regulatory element binding protein‑2 alleviates autophagic dysfunction in NAFLD by Cheng, Chunwei, Deng, Xiaoling, Xu, Keshu

    “…Sterol regulatory element binding protein-2 (SREBP-2) is an important transcription factor in lipid homeostasis. A previous study showed that SREBP-2 also…”
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