Search Results - "Xu, Keshu"
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Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages
Published in Biomedicine & pharmacotherapy (01-05-2020)“…•Scoparone improves hepatic inflammation and autophagy in mice with MCD diet.•Scoparone has an effect on autophag in macrophages, but not…”
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Resolvin D1 attenuates CCl4 Induced Liver Fibrosis by Inhibiting Autophagy-Mediated HSC activation via AKT/mTOR Pathway
Published in Frontiers in pharmacology (20-12-2021)“…Resolvin D1 (RvD1) was previously reported to relieve inflammation and liver damage in several liver diseases, but its potential role in liver fibrosis remains…”
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The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease
Published in Life sciences (1973) (01-10-2022)“…To investigate the effect of cAMP response element-binding protein H (CREBH) on metabolic associated fatty liver disease by regulating sirtuin 3 (SIRT3). Two…”
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Identification and Validation of a Nine-Gene Amino Acid Metabolism-Related Risk Signature in HCC
Published in Frontiers in cell and developmental biology (07-09-2021)“…Background: Hepatocellular carcinoma (HCC) is the world’s second most deadly cancer, and metabolic reprogramming is its distinguishing feature. Among…”
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CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease
Published in Life sciences (1973) (01-08-2020)“…The primary focus of this study was to explore the effects of cyclic AMP response element-binding protein H (CREBH) on the development of nonalcoholic fatty…”
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Gadoxetic Acid-Enhanced Hepatobiliary-Phase Magnetic Resonance Imaging for Pyrrolizidine Alkaloid-Induced Hepatic Sinusoidal Obstruction Syndrome and Association with Liver Function
Published in Scientific reports (04-02-2019)“…Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by pyrrolizidine alkaloids(PAs)-containing herbals. In this study, the aim of our study was to…”
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Prevalence and impact of Sjögren's syndrome in primary biliary cholangitis: a systematic review and meta-analysis
Published in Annals of hepatology (01-11-2022)“…We performed a systematic review and meta-analysis to evaluate the prevalence of concomitant Sjögren's syndrome (SS) with primary biliary cholangitis (PBC) in…”
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p-CREB-1 promotes hepatic fibrosis through the transactivation of transforming growth factor-β1 expression in rats
Published in International journal of molecular medicine (01-08-2016)“…Phosphorylated cAMP-responsive element binding protein-1 (p-CREB-1) is an important transcription factor which has been reported to be implicated in…”
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Evaluation of tumor markers for the differential diagnosis of benign and malignant ascites
Published in Annals of hepatology (01-05-2014)“…AbstractIntroduction. The diagnosis of malignant ascites is a challenging problem in clinical practice, non-invasive techniques should be developed to improve…”
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rAAV2-TGF-β3 Decreases Collagen Synthesis and Deposition in the Liver of Experimental Hepatic Fibrosis Rat
Published in Digestive diseases and sciences (01-10-2010)“…Background/Aims Hepatic fibrosis is one kind of common wound-healing response to chronic liver injury. Transforming growth factor (TGF)-β 3 performs an…”
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Zhikang Capsule ameliorates dextran sodium sulfate-induced colitis by inhibition of inflammation, apoptosis, oxidative stress and MyD88-dependent TLR4 signaling pathway
Published in Journal of ethnopharmacology (04-11-2016)“…Zhikang Capsule (ZKC) is a traditional Chinese medicine (TCM) modified from classic formulas Qi-Li-San (an ancient formula dating to Qing Dynasty) and…”
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12
Improvement of the diffraction properties in holographic polymer dispersed liquid crystal bragg gratings
Published in Optics communications (15-03-2003)“…Holographic polymer dispersed liquid crystal (HPDLC) is a new kind of holographic material. It can be fabricated by the photo-initiated polymerization-induced…”
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CREB family: A significant role in liver fibrosis
Published in Biochimie (01-08-2019)“…Liver fibrosis (LF) is known as a result of the progressive accumulation of extracellular matrix (ECM), and always ascribed to chronic liver diseases. Advanced…”
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COVID-19 and gastrointestinal symptoms
Published in British journal of surgery (01-09-2020)Get full text
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Advances in characterization of SIRT3 deacetylation targets in mitochondrial function
Published in Biochimie (01-12-2020)“…The homeostasis of mitochondrial functional state is intimately in relation with SIRT3 (sirtuin3). SIRT3, the deacetylase mainly anchored in mitochondria, acts…”
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CREBH alleviates mitochondrial oxidative stress through SIRT3 mediating deacetylation of MnSOD and suppression of Nlrp3 inflammasome in NASH
Published in Free radical biology & medicine (01-09-2022)“…Lipotoxicity and unresolved oxidative stress are key drivers of metabolic inflammation in nonalcoholic steatohepatitis (NASH). cAMP-response element binding…”
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Characteristics of LCoS Phase-only spatial light modulator and its applications
Published in Optics communications (15-08-2004)“…The working models of LCoS (Liquid Crystal on Silicon) were optimized in parameter space by simulation. Two modes were selected, which were suitable for phase…”
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Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice
Published in Life sciences (1973) (01-01-2018)“…Baicalin (BA), an active flavonoid compound originating from the herb of Scutellaria baicalensis Georgi, has been previously shown to exert anti-inflammation…”
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Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation
Published in Chemico-biological interactions (25-12-2017)“…Baicalin (BA) is an active flavonoid compound originating from the root of Scutellaria baicalensis Georgi that has been reported to exert anti-inflammation and…”
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Increased expression of sterol regulatory element binding protein‑2 alleviates autophagic dysfunction in NAFLD
Published in International journal of molecular medicine (01-04-2018)“…Sterol regulatory element binding protein-2 (SREBP-2) is an important transcription factor in lipid homeostasis. A previous study showed that SREBP-2 also…”
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