Search Results - "Xu, Kejia"
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Update on protease-activated receptor 2 in inflammatory and autoimmune dermatological diseases
Published in Frontiers in immunology (19-09-2024)“…Protease-activated receptor 2 (PAR2) is a cell-surface receptor expressed in various cell types, including keratinocytes, neurons, immune and inflammatory…”
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Novel Feature Selection Method for Nonlinear Support Vector Regression
Published in Complexity (New York, N.Y.) (01-01-2022)“…The development of sparse techniques presents a major challenge to complex nonlinear high-dimensional data. In this paper, we propose a novel feature selection…”
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Delta Opioid Receptor Activation with Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin Contributes to Synaptic Improvement in Rat Hippocampus against Global Ischemia
Published in Cell transplantation (2021)“…Global cerebral ischemia induced by cardiac arrest usually leads to poor neurological outcomes. Numerous studies have focused on ways to prevent ischemic…”
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Multi-omics analysis reveals neuroinflammation, activated glial signaling, and dysregulated synaptic signaling and metabolism in the hippocampus of aged mice
Published in Frontiers in aging neuroscience (03-11-2022)“…Aging is an intricate biological event that occurs in both vertebrates and invertebrates. During the aging process, the brain, a vulnerable organ, undergoes…”
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Machine learning algorithms to predict intraoperative hemorrhage in surgical patients: a modeling study of real-world data in Shanghai, China
Published in BMC medical informatics and decision making (10-08-2023)“…Prediction tools for various intraoperative bleeding events remain scarce. We aim to develop machine learning-based models and identify the most important…”
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Integrated transcriptomics and metabolomics analysis of the hippocampus reveals altered neuroinflammation, downregulated metabolism and synapse in sepsis-associated encephalopathy
Published in Frontiers in pharmacology (06-09-2022)“…Sepsis-associated encephalopathy (SAE) is an intricated complication of sepsis that brings abnormal emotional and memory dysfunction and increases patients’…”
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Advances in biomaterials as a retinal patch for the repair of rhegmatogenous retinal detachment
Published in Frontiers in bioengineering and biotechnology (17-10-2022)“…Rhegmatogenous retinal detachment (RRD) is the most common retinological emergency that can cause blindness without surgical treatment. RRD occurs when…”
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Successful therapy with interferon alpha‐1b for a relapsing Epstein–Barr virus‐positive mucocutaneous ulcer
Published in Journal of dermatology (01-01-2021)Get full text
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CASCADE_SCAN: mining signal transduction network from high-throughput data based on steepest descent method
Published in BMC bioinformatics (17-05-2011)“…Signal transduction is an essential biological process involved in cell response to environment changes, by which extracellular signaling initiates…”
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10
Immunoregulation in Diabetic Wound Repair with a Photoenhanced Glycyrrhizic Acid Hydrogel Scaffold
Published in Advanced materials (Weinheim) (01-07-2022)“…M1 macrophage accumulation and excessive inflammation are commonly encountered issues in diabetic wounds and can fail in the healing process. Hence, hydrogel…”
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Model order reduction for discrete time-delay systems based on Laguerre function expansion
Published in Linear algebra and its applications (01-07-2024)“…We investigate model order reduction for discrete time-delay systems via orthogonal polynomial expansion in the frequency domain. The transfer function of…”
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The Evolution from a Typical Type‑I CdS/ZnS to Type-II and Z‑Scheme Hybrid Structure for Efficient and Stable Hydrogen Production under Visible Light
Published in ACS sustainable chemistry & engineering (23-03-2020)“…An incompletely covered CdS/ZnS core/shell is synthesized via a simple hydrothermal method. Due to the defect energy levels introduced by zinc vacancies, the…”
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13
Propofol prevents IL‐13‐induced epithelial–mesenchymal transition in human colorectal cancer cells
Published in Cell biology international (01-08-2018)“…Accumulating evidence showed that cytokines are involved in the development of cancer. IL‐13 was showed to induce epithelial–mesenchymal transition and promote…”
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Chicoric Acid Alleviates Colitis via Targeting the Gut Microbiota Accompanied by Maintaining Intestinal Barrier Integrity and Inhibiting Inflammatory Responses
Published in Journal of agricultural and food chemistry (27-03-2024)“…Polyphenols have shown great potential to prevent ulcerative colitis. As a natural plant polyphenol, chicoric acid (CA) has antioxidant and anti-inflammatory…”
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15
Novel EGFR inhibitors against resistant L858R/T790M/C797S mutant for intervention of non-small cell lung cancer
Published in European journal of medicinal chemistry (05-11-2024)“…To overcome C797S mutation, the latest and most common resistance mechanism in the clinical treatment of third-generation EGFR inhibitor, a novel series of…”
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Phosphatidylserine improves aging sepsis survival, modulates gut microbiome, and prevents sepsis-associated encephalopathy
Published in Biomedicine & pharmacotherapy (01-09-2024)“…Aged adults are prone to both short- and long-term complications following sepsis due to ineffective therapy. Phosphatidylserine (PS) is a membrane nutrient…”
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Dahuang Zhechong pill attenuates hepatic sinusoidal capillarization in liver cirrhosis and hepatocellular carcinoma rat model via the MK/integrin signaling pathway
Published in Journal of ethnopharmacology (23-05-2023)“…Dahuang Zhechong pill (DHZCP), a traditional Chinese medicine, was derived from the famous book Unk “Synopsis of Prescriptions of the Golden Chamber” during…”
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Discovery of novel fructose-1,6-bisphosphatase inhibitors bearing benzimidazole scaffold using a dual-ligand molecular docking model
Published in European journal of medicinal chemistry (05-12-2024)“…Fructose-1,6-bisphosphatase (FBPase) is an emerging target in gluconeogenesis, inhibitors of which would be an effective treatment for elevated fasting blood…”
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Real-time low-complexity diversity combining algorithm for free space coherent optical communication systems over atmospheric turbulence channel
Published in Optics express (20-11-2023)“…A novel diversity combining scheme, in conjunction with the complex-valued decision-directed least mean square (CV-DD-LMS) algorithm, is evaluated, and a…”
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20
Rebar binding point location method based on improved YOLOv5 and thinning algorithm
Published in Measurement : journal of the International Measurement Confederation (01-01-2025)“…•This paper proposes a rebar binding point location algorithm based on improved yolov5 and thinning algorithm.•The algorithm can classify the rebar of…”
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