Search Results - "Xu, Kangping"
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Preparation of new halogenated diphenyl pyrazine analogs in Escherichia coli by a mono-module fungal nonribosomal peptide synthetase from Penicillium herquei
Published in Tetrahedron letters (08-08-2018)“…[Display omitted] •The biocatalytic approaches to obtain diphenyl pyrazine analogs.•Exploration of the catalytic ability of HqlA towards tyrosine…”
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2
Rhytidhylides A and B, Two New Phthalide Derivatives from the Endophytic Fungus Rhytidhysteron sp. BZM-9
Published in Molecules (Basel, Switzerland) (09-10-2021)“…Two new phthalide derivatives, rhytidhylides A (1) and B (2), together with ten known compounds (3–12) were isolated from cultures of Rhytidhysteron sp. BZM-9,…”
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3
Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers
Published in Journal of ethnopharmacology (28-04-2014)“…Hericium is a genus of mushrooms (fungus) in the Hericiaceae family. Hericium erinaceus (HE) has been used for the treatment of digestive diseases for over…”
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Biflavonoids from Selaginella doederleinii as Potential Antitumor Agents for Intervention of Non-Small Cell Lung Cancer
Published in Molecules (Basel, Switzerland) (05-09-2021)“…Four new biflavonoids ( - ) were isolated from together with a known biflavonoid derivative ( ). Their structures contained a rare linker of individual…”
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5
Synthesis of Halogenated Diphenylpiperazines from L-Tyrosine Derivatives by Biotransformation
Published in Chemistry letters (01-01-2022)“…Piperazine-containing compounds tend to exhibit good biological activities. In this study, four novel halogenated diphenylpiperazines were biosynthesized in…”
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Strategies for Prevention and Control of Vibriosis in Asian Fish Culture
Published in Vaccines (Basel) (31-12-2022)“…It is estimated that vibriosis account for about half of the economic losses in Asian fish culture. Consequently, the prevention and control of vibriosis is…”
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Brasesquilignan A–E, Five New Furofurans Lignans from Selaginella braunii Baker
Published in Molecules (Basel, Switzerland) (26-09-2022)“…Five new furofurans lignans, Brasesquilignan A–E (1–5), were isolated from the aqueous ethanol extract of Selaginella braunii Baker. Their structures were…”
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A New Stilbenoid from Caryopteris incana
Published in Chemistry of natural compounds (01-03-2022)“…A new stilbenoid, methyl 2,4-dihydroxy-6-(4-hydroxyphenethyl)-3-methylbenzoate ( 1 ), along with 11 known compounds, cirsimaritin ( 2 ), cirsiliol ( 3 ),…”
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Diaportones A–C: Three New Metabolites From Endophytic Fungus Diaporthe foeniculina BZM-15
Published in Frontiers in chemistry (19-11-2021)“…Phytochemical investigation of Diaporthe foeniculina BZM-15 led to one new γ -butyrolactone derivative, diaportone A ( 1 ), one cyclopentenone derivative,…”
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A new bird record in China: Moustached Warbler(Acrocephalus melanopogon) and its song characteristics
Published in Journal of arid land (01-04-2017)“…Moustached Warbler(Acrocephalus melanopogon), belonging to the genus of Acrocephalus and the family of Acrocephalidae, breeds widely but locally in the warm…”
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11
Elucidation of a Dearomatization Route in the Biosynthesis of Oxysporidinone Involving a TenA‐like Cytochrome P450 Enzyme
Published in Angewandte Chemie International Edition (19-06-2023)“…Oxidative dearomatization of phenols is an important transformation for synthesis of complex molecules. Oxysporidinone and related 2‐pyridones feature a…”
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12
Activation of a Silent Gene Cluster from the Endophytic Fungus Talaromyces sp. Unearths Cryptic Azaphilone Metabolites
Published in Journal of agricultural and food chemistry (17-07-2024)“…Fungal azaphilones have attracted widespread attention due to their significant potential as sources of food pigments and pharmaceuticals. Genome mining and…”
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Challenging Aromaticity: Revealing a Thioesterase Domain in a Fungal Nonreducing Polyketide Synthase Governing the Production of 3‑Methylene Isochromanone
Published in Organic letters (02-08-2024)“…Thioesterase (TE) domain exerts a great influence over the structure of the final product and TE-released nonreduced polyketides (nrPKs) retain aromaticity…”
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14
Extracts of Cordyceps sinensis inhibit breast cancer growth through promoting M1 macrophage polarization via NF-κB pathway activation
Published in Journal of ethnopharmacology (05-10-2020)“…Cordyceps sinensis is a traditional Chinese medicine. It is widely reported that Cordyceps sinensis has inhibitory effect on tumor growth and immunoregulation…”
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15
Design, synthesis and evaluation of nitric oxide releasing derivatives of 2,4-diaminopyrimidine as novel FAK inhibitors for intervention of metastatic triple-negative breast cancer
Published in European journal of medicinal chemistry (15-03-2023)“…To search for novel medicines for intervention of triple-negative breast cancer (TNBC), a series of phenylsulfonyl furoxan-based 2,4-diaminopyrimidine…”
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16
Discovery of novel chloropyramine-cinnamic acid hybrids as potential FAK inhibitors for intervention of metastatic triple-negative breast cancer
Published in Bioorganic & medicinal chemistry (15-07-2022)“…[Display omitted] •7d exhibited low micromolar antiproliferative activity against TNBC cells but sparing non-tumor breast cells.•7d significantly inhibited…”
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A Single Amino Acid Switch Alters the Prenyl Donor Specificity of a Fungal Aromatic Prenyltransferase toward Biflavonoids
Published in Organic letters (15-01-2021)“…Biflavonoids are pharmaceutically important compounds. Prenylation usually improves bioactivity; however, prenylated biflavonoids are rare in nature. Here, we…”
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Selagintriflavonoids with BACE1 inhibitory activity from the fern Selaginella doederleinii
Published in Phytochemistry (Oxford) (01-02-2017)“…Eight triflavonoids, selagintriflavonoids A-H, were isolated from whole herbs of Selaginella doederleinii. The structures of compounds selagintriflavonoids A-C…”
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Hypoglycemic triterpenoid glycosides from Cyclocarya paliurus (Sweet Tea Tree)
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] •Eight new dammarane triterpenoid glycosides were isolated from the leaves of Cyclocarya paliurus (family Juglandaceae).•The absolute…”
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Dearomative gem -diprenylation of hydroxynaphthalenes by an engineered fungal prenyltransferase
Published in RSC advances (22-09-2022)“…Prenylation usually improves structural diversity and bioactivity in natural products. Unlike the discovered enzymatic gem -diprenylation of mono- and…”
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