Search Results - "Xu, Jiuzhi"
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Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling
Published in The EMBO journal (01-04-2020)“…The Hippo–YAP signaling pathway plays an essential role in epithelial cells during intestinal regeneration and tumorigenesis. However, the molecular mechanism…”
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The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease
Published in Cell research (01-10-2020)“…Mammary and extramammary Paget’s Diseases (PD) are a malignant skin cancer characterized by the appearance of Paget cells. Although easily diagnosed, its…”
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3
A review of HSV pathogenesis, vaccine development, and advanced applications
Published in Molecular biomedicine (29-08-2024)“…Herpes simplex virus (HSV), an epidemic human pathogen threatening global public health, gains notoriety for its complex pathogenesis that encompasses lytic…”
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Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hh Signaling Pathway
Published in Journal of investigative dermatology (01-05-2017)“…Hair follicles (HFs) undergo precisely regulated cycles of active regeneration (anagen), involution (catagen), and relative quiescence (telogen). Hair follicle…”
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Hormone-Responsive BMP Signaling Expands Myoepithelial Cell Lineages and Prevents Alveolar Precocity in Mammary Gland
Published in Frontiers in cell and developmental biology (15-07-2021)“…Myoepithelial and luminal cells synergistically expand in the mammary gland during pregnancy, and this process is precisely governed by hormone-related…”
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Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation
Published in iScience (18-03-2022)“…The Mammary gland undergoes complicated epithelial remodeling to form lobuloalveoli during pregnancy, in which basal epithelial cells remarkably increase to…”
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Cycling Stem Cells Are Radioresistant and Regenerate the Intestine
Published in Cell reports (Cambridge) (28-07-2020)“…A certain number of epithelial cells in intestinal crypts are DNA damage resistant and contribute to regeneration. However, the cellular mechanism underlying…”
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Heterogeneous polarization-integrated medium wave infrared HgCdTe focal plane array detector with pixel-wise Al gratings
Published in Optical materials express (01-11-2024)“…Real-time polarization imaging plays a crucial role in camouflaged target detection. However, large optical crosstalk restricts the development of…”
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MicroRNA-31 Reduces Inflammatory Signaling and Promotes Regeneration in Colon Epithelium, and Delivery of Mimics in Microspheres Reduces Colitis in Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2019)“…Levels of microRNA 31 (MIR31) are increased in intestinal tissues from patients with inflammatory bowel diseases and colitis-associated neoplasias. We…”
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mTORC2‐AKT signaling to PFKFB2 activates glycolysis that enhances stemness and tumorigenicity of intestinal epithelial cells
Published in The FASEB journal (15-03-2024)“…Although elevated glycolysis has been widely recognized as a hallmark for highly proliferating cells like stem cells and cancer, its regulatory mechanisms are…”
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Arachidonic Acid Promotes Intestinal Regeneration by Activating WNT Signaling
Published in Stem cell reports (11-08-2020)“…Intestinal regeneration is crucial for functional restoration after injury, and nutritional molecules can play an important role in this process. Here, we…”
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Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis
Published in Cell research (01-07-2022)“…Diet can impact on gut health and disease by modulating intestinal stem cells (ISCs). However, it is largely unknown if and how the ISC niche responds to diet…”
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Excessive nucleic acid R-loops induce mitochondria-dependent epithelial cell necroptosis and drive spontaneous intestinal inflammation
Published in Proceedings of the National Academy of Sciences - PNAS (02-01-2024)“…Oxidative stress, which can be activated by a variety of environmental risk factors, has been implicated as an important pathogenic factor for inflammatory…”
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Lactobacillus paracasei L9 improves colitis by expanding butyrate-producing bacteria that inhibit the IL-6/STAT3 signaling pathway
Published in Food & function (01-11-2021)“…Inflammatory bowel disease (IBD) is a chronic intestinal inflammation that is currently incurable. Increasing evidence indicates that supplementation with…”
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Intensity profile stabilities of high order vectorial modes of optical fibers
Published in Optik (Stuttgart) (01-11-2017)“…It is known that the high order vectorial modes of ideally circular optical fibers possess cylindrical symmetries in electric field distributions as well as…”
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Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state
Published in Theranostics (01-01-2022)“…Dysregulation of signaling that governs self-renewal and differentiation of intestinal stem cells (ISCs) is a major cause of colorectal cancer (CRC) initiation…”
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MiR-22 modulates brown adipocyte thermogenesis by synergistically activating the glycolytic and mTORC1 signaling pathways
Published in Theranostics (01-01-2021)“…Brown adipose tissue (BAT) dissipates chemical energy as heat and has the potential to be a protective strategy to prevent obesity. microRNAs (miRNAs) are…”
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