Search Results - "Xu, Jiheng"
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Overexpressed miR-200a promotes bladder cancer invasion through direct regulating Dicer/miR-16/JNK2/MMP-2 axis
Published in Oncogene (01-02-2020)“…Invasive bladder cancer (BC) is one of the most lethal malignant urological tumors. Although miR-200a has been reported as an onco-miRNA that targets the PTEN…”
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An improved particle swarm optimization method for locating time-varying indoor particle sources
Published in Building and environment (01-01-2019)“…The indoor transmission of airborne particles can spread disease and have health-related and even life-threatening effects on occupants, thus necessitating…”
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Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression
Published in Cellular and molecular life sciences : CMLS (01-01-2020)“…Cancer stem cells (CSC) are highly associated with poor prognosis in cancer patients. Our previous studies report that isorhapontigenin (ISO) down-regulates…”
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Lnc00892 competes with c-Jun to block NCL transcription, reducing the stability of RhoA/RhoC mRNA and impairing bladder cancer invasion
Published in Oncogene (02-12-2021)“…Metastasis of bladder cancer is a complex process and has been associated with poor clinical outcomes. However, the mechanisms of bladder cancer metastasis…”
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SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation
Published in International journal of molecular sciences (19-10-2022)“…SOX2, a member of the SRY-related HMG-box (SOX) family, is abnormally expressed in many tumors and associated with cancer stem cell-like properties. Previous…”
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Isorhapontigenin inhibition of basal muscle-invasive bladder cancer attributed to its downregulation of SNHG1 and DNMT3b
Published in BMC cancer (15-06-2024)“…Bladder cancer (BC) is among the most prevalent malignant urothelial tumors globally, yet the prognosis for patients with muscle-invasive bladder cancer (MIBC)…”
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The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein
Published in Cell death and differentiation (01-02-2020)“…Sex-determining region Y-box 2 (SOX2), a well-known stemness biomarker, is highly expressed in a variety of cancers, including human highly invasive bladder…”
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NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein
Published in Neoplasia (New York, N.Y.) (01-09-2017)“…BACKGROUND: Since invasive bladder cancer (BC) is one of the most lethal urological malignant tumors worldwide, understanding the molecular mechanisms that…”
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ISO-upregulated BECN1 specifically promotes LC3B-dependent autophagy and anticancer activity in invasive bladder cancer
Published in Translational oncology (01-01-2025)“…•our results demonstrate that by activating c-Myc/miR-613/NCL axis, ISO treatment results in BECN1 posttranscriptional upregulation, which specific initiates…”
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Induction of RAC1 protein translation and MKK7/JNK-dependent autophagy through dicer/miR-145/SOX2/miR-365a axis contributes to isorhapontigenin (ISO) inhibition of human bladder cancer invasion
Published in Cell death & disease (31-08-2022)“…Although our previous studies have identified that isorhapontigenin (ISO) is able to initiate autophagy in human bladder cancer (BC) cells by activating…”
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Research on evacuation simulation of underground commercial street based on reciprocal velocity obstacle model
Published in Journal of Asian architecture and building engineering (02-01-2022)“…The current study evaluates the influence of different exit quantity and location on evacuation efficiency of underground commercial street, and analyzes the…”
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NF-κB1 p50 stabilizes HIF-1α protein through suppression of ATG7-dependent autophagy
Published in Cell death & disease (27-12-2022)“…The function and underlying mechanisms of p50 in the regulation of protein expression is much less studied because of its lacking of transactivation domain. In…”
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Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation
Published in Journal of experimental & clinical cancer research (17-02-2024)“…Phosphatase and tensin homolog deleted on chromosome ten (PTEN) serves as a powerful tumor suppressor, and has been found to be downregulated in human bladder…”
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lncRNA SNHG1 Promotes Basal Bladder Cancer Invasion via Interaction with PP2A Catalytic Subunit and Induction of Autophagy
Published in Molecular therapy. Nucleic acids (04-09-2020)“…Although basal muscle-invasive bladder cancers (MIBCs) are predominant, are more aggressive, and have bad prognoses, molecular mechanisms underlying how basal…”
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Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer
Published in Cell adhesion & migration (01-01-2019)“…Our previous studies have demonstrated that XIAP promotes bladder cancer metastasis through upregulating RhoGDIβ/MMP-2 pathway. However, the molecular…”
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CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells
Published in Oncogene (01-04-2019)“…Over half a million US residents are suffering with bladder cancer (BC), which costs a total $4 billion in treatment annually. Although recent studies report…”
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ATG7 Promotes Bladder Cancer Invasion via Autophagy‐Mediated Increased ARHGDIB mRNA Stability
Published in Advanced science (01-11-2021)Get full text
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ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion
Published in Molecular therapy. Nucleic acids (07-09-2018)“…Our most recent studies demonstrate that miR-137 is downregulated in human bladder cancer (BC) tissues, while treatment of human BC cells with isorhapontigenin…”
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Dynamical source term estimation in a multi-compartment building under time-varying airflow
Published in Building and environment (01-08-2019)“…In the case of an airborne contaminant release, it is critical to know the source location and emission rate as soon as possible and take proper actions to…”
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