Search Results - "Xu, Guowang"

Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography–mass spectrometry by Zheng, Fujian, Zhao, Xinjie, Zeng, Zhongda, Wang, Lichao, Lv, Wangjie, Wang, Qingqing, Xu, Guowang

“…Untargeted methods are typically used in the detection and discovery of small organic compounds in metabolomics research, and ultra-high-performance liquid…”
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Effects of pre-analytical processes on blood samples used in metabolomics studies by Yin, Peiyuan, Lehmann, Rainer, Xu, Guowang

“…Every day, analytical and bio-analytical chemists make sustained efforts to improve the sensitivity, specificity, robustness, and reproducibility of their…”
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Current state-of-the-art of nontargeted metabolomics based on liquid chromatography–mass spectrometry with special emphasis in clinical applications by Yin, Peiyuan, Xu, Guowang

“…•Current state-of-the-art on LC–MS based metabolomics is reviewed.•Recent advances to increase the metabolite coverage and improve the data quality are…”
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Proline metabolism in cancer by Geng, Pengyu, Qin, Wangshu, Xu, Guowang

“…Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the…”
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Recent advances in development and characterization of stationary phases for hydrophilic interaction chromatography by Qiao, Lizhen, Shi, Xianzhe, Xu, Guowang

“…•Development of HILIC stationary phases in the past 5 years is reviewed.•Different methods for characterizing HILIC systems are introduced.•Comparison and…”
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Understanding the link between sleep and health using metabolomics by Xu, Liyue, Xu, Guowang, Han, Fang

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Recent advances in using mass spectrometry for mitochondrial metabolomics and lipidomics - A review by Liu, Xinyu, Xu, Guowang

“…Metabolomics and lipidomics generally targets a huge number of intermediate and end products of cellular metabolism in body fluids, tissues, and cells etc. At…”
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Mass-spectrometry-based metabolomics analysis for foodomics by Hu, Chunxiu, Xu, Guowang

“…•The current state of MS-based metabolic profiling methods in food science.•Multi-disciplinary approaches needed to link food and diet with health and…”
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Improving the lipid extraction yield from Chlorella based on the controllable electroporation of cell membrane by pulsed electric field by Zhang, Ruobing, Gu, Xinyu, Xu, Guowang, Fu, Xian

“…•Electric field strength (E) and the specific energy input are the decisive factors.•PEF treatment increased the lipid extraction yield by up to 166.67%•An…”
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Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices by Alseekh, Saleh, Aharoni, Asaph, Brotman, Yariv, Contrepois, Kévin, D’Auria, John, Ewald, Jan, C. Ewald, Jennifer, Fraser, Paul D., Giavalisco, Patrick, Hall, Robert D., Heinemann, Matthias, Link, Hannes, Luo, Jie, Neumann, Steffen, Nielsen, Jens, Perez de Souza, Leonardo, Saito, Kazuki, Sauer, Uwe, Schroeder, Frank C., Schuster, Stefan, Siuzdak, Gary, Skirycz, Aleksandra, Sumner, Lloyd W., Snyder, Michael P., Tang, Huiru, Tohge, Takayuki, Wang, Yulan, Wen, Weiwei, Wu, Si, Xu, Guowang, Zamboni, Nicola, Fernie, Alisdair R.

“…Mass spectrometry-based metabolomics approaches can enable detection and quantification of many thousands of metabolite features simultaneously. However,…”
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Data analysis methods for defining biomarkers from omics data by Li, Chao, Gao, Zhenbo, Su, Benzhe, Xu, Guowang, Lin, Xiaohui

“…Omics mainly includes genomics, epigenomics, transcriptomics, proteomics and metabolomics. The rapid development of omics technology has opened up new ways to…”
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USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma by Ning, Zhen, Guo, Xin, Liu, Xiaolong, Lu, Chang, Wang, Aman, Wang, Xiaolin, Wang, Wen, Chen, Huan, Qin, Wangshu, Liu, Xinyu, Zhou, Lina, Ma, Chi, Du, Jian, Lin, Zhikun, Luo, Haifeng, Otkur, Wuxiyar, Qi, Huan, Chen, Di, Xia, Tian, Liu, Jiwei, Tan, Guang, Xu, Guowang, Piao, Hai-long

“…Elevated de novo lipogenesis is considered to be a crucial factor in hepatocellular carcinoma (HCC) development. Herein, we identify ubiquitin-specific…”
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Rational Synthesis of Aptamer-Functionalized Polyethylenimine-Modified Magnetic Graphene Oxide Composites for Highly Efficient Enrichment and Comprehensive Metabolomics Analysis of Exosomes by Chang, Mengmeng, Wang, Qingqing, Qin, Wangshu, Shi, Xianzhe, Xu, Guowang

“…Exosomes, which are phospholipid bilayer nanovesicles, can transfer their content to recipient cells, playing a crucial role in intercellular communication…”
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Metabolic Characterization of Hepatocellular Carcinoma Using Nontargeted Tissue Metabolomics by Huang, Qiang, Tan, Yexiong, Yin, Peiyuan, Ye, Guozhu, Gao, Peng, Lu, Xin, Wang, Hongyang, Xu, Guowang

“…Hepatocellular carcinoma has a poor prognosis due to its rapid development and early metastasis. In this report, we characterized the metabolic features of…”
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Pseudotargeted Metabolomics Method and Its Application in Serum Biomarker Discovery for Hepatocellular Carcinoma Based on Ultra High-Performance Liquid Chromatography/Triple Quadrupole Mass Spectrometry by Chen, Shili, Kong, Hongwei, Lu, Xin, Li, Yong, Yin, Peiyuan, Zeng, Zhongda, Xu, Guowang

“…Untargeted analysis performed using full-scan mass spectrometry (MS) coupled with liquid chromatography (LC) is commonly used in metabolomics. Although they…”
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Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma by Tang, Ling, Zeng, Jun, Geng, Pengyu, Fang, Chengnan, Wang, Yang, Sun, Mingju, Wang, Changsong, Wang, Jiao, Yin, Peiyuan, Hu, Chunxiu, Guo, Lei, Yu, Jane, Gao, Peng, Li, Enyou, Zhuang, Zhengping, Xu, Guowang, Liu, Yang

“…Metabolic reprogramming is frequently identified in hepatocellular carcinoma (HCC), which is the most common type of liver malignancy. The reprogrammed…”
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Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection by Wu, Qi, Zhou, Lina, Sun, Xin, Yan, Zhongfang, Hu, Chunxiu, Wu, Junping, Xu, Long, Li, Xue, Liu, Huiling, Yin, Peiyuan, Li, Kuan, Zhao, Jieyu, Li, Yanli, Wang, Xiaolin, Li, Yu, Zhang, Qiuyang, Xu, Guowang, Chen, Huaiyong

“…Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-like coronavirus are a potential threat to global health. However, reviews of the long-term…”
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Comprehensive metabolic profiling of Parkinson's disease by liquid chromatography-mass spectrometry by Shao, Yaping, Li, Tianbai, Liu, Zheyi, Wang, Xiaolin, Xu, Xiaojiao, Li, Song, Xu, Guowang, Le, Weidong

“…Parkinson's disease (PD) is a prevalent neurological disease in the elderly with increasing morbidity and mortality. Despite enormous efforts, rapid and…”
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Simultaneous metabolomics and lipidomics analysis based on novel heart-cutting two-dimensional liquid chromatography-mass spectrometry by Wang, Shuangyuan, Zhou, Lina, Wang, Zhichao, Shi, Xianzhe, Xu, Guowang

“…Increasing metabolite coverage by combining data from different platforms or methods can improve understanding of related metabolic mechanisms and the…”
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Selective oxidation of methane to methanol using AuPd@ZIF-8 by Xu, Guowang, Yu, Aimin, Xu, Yongjun, Sun, Chenghua

“…Selective methane conversion to alcohol derivatives remains an open challenge. Here, bimetallic catalyst, AuPd@ZIF-8, has been synthesized and demonstrated as…”
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