Search Results - "Xu, Diannan"
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5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers
Published in Cell research (01-10-2017)“…DNA modifications such as 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are epigenetic marks known to affect global gene efpression in mammals…”
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Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers
Published in Cell research (01-07-2019)“…In the initial published version of this article, there was a mistake in the P value for the correlation between gene-expression changes and 5 hmC changes in…”
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H19/miR‐148a/USP4 axis facilitates liver fibrosis by enhancing TGF‐β signaling in both hepatic stellate cells and hepatocytes
Published in Journal of cellular physiology (01-06-2019)“…Liver fibrosis is a wound‐healing response represented by excessive extracellular matrix deposition. Activation of hepatic stellate cell (HSC) is the critical…”
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DNMT1 mediated promoter methylation of GNAO1 in hepatoma carcinoma cells
Published in Gene (30-07-2018)“…Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers worldwide and has recently become the second most common cause of cancer-related…”
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Positive feedback loop of YB-1 interacting with Smad2 promotes liver fibrosis
Published in Biochemical and biophysical research communications (18-03-2017)“…Y-box binding protein (YB-1), known as a multifunctional cellular protein in various biological processes, was recently reported to be associated with liver…”
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A single nucleotide variant in microRNA-1269a promotes the occurrence and process of hepatocellular carcinoma by targeting to oncogenes SPATS2L and LRP6
Published in Bulletin du cancer (01-04-2017)“…Hepatocellular carcinoma (HCC) is one of the malignant and lethal cancers. Single nucleotide polymorphisms (SNPs) in microRNAs(miRNAs) can affect the…”
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Neural precursor cell expressed, developmentally downregulated 8-activating enzyme inhibitor MLN4924 sensitizes colorectal cancer cells to oxaliplatin by inducing DNA damage, G2 cell cycle arrest and apoptosis
Published in Molecular medicine reports (01-05-2017)“…Oxaliplatin-based chemotherapy is a primary treatment for patients with metastatic colorectal cancer (CRC); however, its efficacy is limited. Therefore, novel…”
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Downregulated miRNA-1269a variant (rs73239138) decreases the susceptibility to gastric cancer via targeting ZNF70
Published in Oncology letters (01-12-2017)“…Although emerging evidence has indicated that single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) are associated with susceptibility to gastric…”
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Global transcriptome-wide analysis of the function of GDDR in acute gastric lesions
Published in Molecular medicine reports (01-12-2017)“…Acute gastric lesions induced by stress are frequent occurrences in medical establishments. The gastric dramatic downrelated gene (GDDR) is a secreted protein,…”
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Downregulated miRNA-1269a variant
Published in Oncology letters (01-12-2017)“…Although emerging evidence has indicated that single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) are associated with susceptibility to gastric…”
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Inhibition of pro-collagen I expression by oxymatrine in hepatic stellate cells is mediated via nuclear translocation of Y-box binding protein 1
Published in Molecular medicine reports (01-12-2015)“…Accumulating evidence indicated that oxymatrine (OMT), an alkaloid compound from the Chinese medicinal herb Sophora flavescens, exhibits activity against…”
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