Search Results - "Xu, Chunxiao"

Association of 24-h urinary sodium excretion with microalbuminuria in a Chinese population by Xu, Chunxiao, Du, Xiaofu, Fang, Le, Zhong, Jieming, Lu, Feng

“…To assess the relationship of sodium, potassium and the ratio of sodium to potassium (Na/K) with albuminuria, a cross-sectional study was carried out in China…”
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Monitoring and analysis of abandoned cropland in the Karst Plateau of eastern Yunnan, China based on Landsat time series images by Zhao, Zhe, Wang, Jiasheng, Wang, Limeng, Rao, Xun, Ran, Wenjing, Xu, Chunxiao

“…•A monitoring method of abandoned cropland based on Landsat images was proposed.•The cropland abandonment in the study area showed a trend of rapid growth and…”
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Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer by Tricker, Erin M, Xu, Chunxiao, Uddin, Sharmeen, Capelletti, Marzia, Ercan, Dalia, Ogino, Atsuko, Pratilas, Christine A, Rosen, Neal, Gray, Nathanael S, Wong, Kwok-Kin, Jänne, Pasi A

“…Irreversible pyrimidine-based EGFR inhibitors, including WZ4002, selectively inhibit both EGFR-activating and EGFR inhibitor-resistant T790M mutations more…”
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Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers by Cottini, Francesca, Hideshima, Teru, Xu, Chunxiao, Sattler, Martin, Dori, Martina, Agnelli, Luca, ten Hacken, Elisa, Bertilaccio, Maria Teresa, Antonini, Elena, Neri, Antonino, Ponzoni, Maurilio, Marcatti, Magda, Richardson, Paul G, Carrasco, Ruben, Kimmelman, Alec C, Wong, Kwok-Kin, Caligaris-Cappio, Federico, Blandino, Giovanni, Kuehl, W Michael, Anderson, Kenneth C, Tonon, Giovanni

“…Tumor cells of epithelial origin present rampant DNA damage but do not undergo apoptosis due to inactivation of TP53. Understanding the mechanisms by which…”
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Comprehensive Pan-Cancer Analysis Confirmed That ATG5 Promoted the Maintenance of Tumor Metabolism and the Occurrence of Tumor Immune Escape by Xu, Chunxiao, Zang, Yusheng, Zhao, Yuxiang, Cui, Weiqiang, Zhang, Hong, Zhu, Yingcui, Xu, Man

“…Autophagy related protein 5 (ATG5) is an important autophagosome formation related protein, and its involvement in the biological process of autophagy has been…”
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Identification of Five Interferon-Induced Cellular Proteins That Inhibit West Nile Virus and Dengue Virus Infections by Jiang, Dong, Weidner, Jessica M, Qing, Min, Pan, Xiao-Ben, Guo, Haitao, Xu, Chunxiao, Zhang, Xianchao, Birk, Alex, Chang, Jinhong, Shi, Pei-Yong, Block, Timothy M, Guo, Ju-Tao

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response by Chen, Zhao, Cheng, Katherine, Walton, Zandra, Wang, Yuchuan, Ebi, Hiromichi, Shimamura, Takeshi, Liu, Yan, Tupper, Tanya, Ouyang, Jing, Li, Jie, Gao, Peng, Woo, Michele S., Xu, Chunxiao, Yanagita, Masahiko, Altabef, Abigail, Wang, Shumei, Lee, Charles, Nakada, Yuji, Peña, Christopher G., Sun, Yanping, Franchetti, Yoko, Yao, Catherine, Saur, Amy, Cameron, Michael D., Nishino, Mizuki, Hayes, D. Neil, Wilkerson, Matthew D., Roberts, Patrick J., Lee, Carrie B., Bardeesy, Nabeel, Butaney, Mohit, Chirieac, Lucian R., Costa, Daniel B., Jackman, David, Sharpless, Norman E., Castrillon, Diego H., Demetri, George D., Jänne, Pasi A., Pandolfi, Pier Paolo, Cantley, Lewis C., Kung, Andrew L., Engelman, Jeffrey A., Wong, Kwok-Kin

“…In parallel with an ongoing human clinical trial, genetically engineered mouse models of lung cancer with different genetic alterations are treated with…”
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Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition by Soucheray, Margaret, Capelletti, Marzia, Pulido, Inés, Kuang, Yanan, Paweletz, Cloud P, Becker, Jeffrey H, Kikuchi, Eiki, Xu, Chunxiao, Patel, Tarun B, Al-Shahrour, Fatima, Carretero, Julián, Wong, Kwok-Kin, Jänne, Pasi A, Shapiro, Geoffrey I, Shimamura, Takeshi

“…Non-small cell lung cancers (NSCLC) that have developed resistance to EGF receptor (EGFR) tyrosine kinase inhibitor (TKI), including gefitinib and erlotinib,…”
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Research on Environmental Responsibility Behavior of Tourists in Seaside Ecological Scenic Spots--The Case of Shenzhen Bay Park by Li, Ping, Xu, Chunxiao, Zhou, Qi

“…There is a symbiotic relationship between tourists’ environmental responsibility behavior and tourism’s ecological environment. If tourists consciously…”
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Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR by QINGSONG LIU, CHUNXIAO XU, ERCAN, Dalia, NIEPEL, Mario, THOREEN, Carson C, KANG, Seong A, PATRICELLI, Matthew P, YUCHUAN WANG, TUPPER, Tanya, ALTABEF, Abigail, KAWAMURA, Hidemasa, HELD, Kathryn D, KIRUBAKARAN, Sivapriya, CHOU, Danny M, ELLEDGE, Stephen J, JANNE, Pasi A, WONG, Kwok-Kin, SABATINI, David M, GRAY, Nathanael S, XIN ZHANG, HUR, Wooyoung, YAN LIU, KWIATKOWSKI, Nicholas P, JINHUA WANG, WESTOVER, Kenneth D, PENG GAO

“…mTOR is a highly conserved serine/threonine protein kinase that serves as a central regulator of cell growth, survival, and autophagy. Deregulation of the…”
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Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors by Ercan, Dalia, Xu, Chunxiao, Yanagita, Masahiko, Monast, Calixte S, Pratilas, Christine A, Montero, Joan, Butaney, Mohit, Shimamura, Takeshi, Sholl, Lynette, Ivanova, Elena V, Tadi, Madhavi, Rogers, Andrew, Repellin, Claire, Capelletti, Marzia, Maertens, Ophélia, Goetz, Eva M, Letai, Anthony, Garraway, Levi A, Lazzara, Matthew J, Rosen, Neal, Gray, Nathanael S, Wong, Kwok-Kin, Jänne, Pasi A

“…The clinical efficacy of epidermal growth factor receptor (EGFR) kinase inhibitors is limited by the development of drug resistance. The irreversible EGFR…”
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Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2 by Zhang, Haikuo, Fillmore Brainson, Christine, Koyama, Shohei, Redig, Amanda J., Chen, Ting, Li, Shuai, Gupta, Manav, Garcia-de-Alba, Carolina, Paschini, Margherita, Herter-Sprie, Grit S., Lu, Gang, Zhang, Xin, Marsh, Bryan P., Tuminello, Stephanie J., Xu, Chunxiao, Chen, Zhao, Wang, Xiaoen, Akbay, Esra A., Zheng, Mei, Palakurthi, Sangeetha, Sholl, Lynette M., Rustgi, Anil K., Kwiatkowski, David J., Diehl, J Alan, Bass, Adam J., Sharpless, Norman E., Dranoff, Glenn, Hammerman, Peter S., Ji, Hongbin, Bardeesy, Nabeel, Saur, Dieter, Watanabe, Hideo, Kim, Carla F., Wong, Kwok-Kin

“…Adenosquamous lung tumours, which are extremely poor prognosis, may result from cellular plasticity. Here, we demonstrate lineage switching of KRAS+ lung…”
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Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer by Hammerman, Peter S, Sos, Martin L, Ramos, Alex H, Xu, Chunxiao, Dutt, Amit, Zhou, Wenjun, Brace, Lear E, Woods, Brittany A, Lin, Wenchu, Zhang, Jianming, Deng, Xianming, Lim, Sang Min, Heynck, Stefanie, Peifer, Martin, Simard, Jeffrey R, Lawrence, Michael S, Onofrio, Robert C, Salvesen, Helga B, Seidel, Danila, Zander, Thomas, Heuckmann, Johannes M, Soltermann, Alex, Moch, Holger, Koker, Mirjam, Leenders, Frauke, Gabler, Franziska, Querings, Silvia, Ansén, Sascha, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Brustugun, Odd Terje, Helland, Aslaug, Petersen, Iver, Clement, Joachim H, Groen, Harry, Timens, Wim, Sietsma, Hannie, Stoelben, Erich, Wolf, Jürgen, Beer, David G, Tsao, Ming Sound, Hanna, Megan, Hatton, Charles, Eck, Michael J, Janne, Pasi A, Johnson, Bruce E, Winckler, Wendy, Greulich, Heidi, Bass, Adam J, Cho, Jeonghee, Rauh, Daniel, Gray, Nathanael S, Wong, Kwok-Kin, Haura, Eric B, Thomas, Roman K, Meyerson, Matthew

“…While genomically targeted therapies have improved outcomes for patients with lung adenocarcinoma, little is known about the genomic alterations which drive…”
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Identification of Three Interferon-Inducible Cellular Enzymes That Inhibit the Replication of Hepatitis C Virus by Jiang, Dong, Guo, Haitao, Xu, Chunxiao, Chang, Jinhong, Gu, Baohua, Wang, Lijuan, Block, Timothy M, Guo, Ju-Tao

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effects of APOA5 -1131T>C (rs662799) on fasting plasma lipids and risk of metabolic syndrome: evidence from a case-control study in China and a meta-analysis by Xu, Chunxiao, Bai, Rongpan, Zhang, Dandan, Li, Zhenli, Zhu, Honghong, Lai, Maode, Zhu, Yimin

“…The apolipoprotein A5 (APOA5) gene -1131T>C (rs662799) has been suggested to be involved in the pathway of lipid homeostasis and the development of metabolic…”
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Transient growth in turbulent particle-laden channel flow by Song, Yang, Xu, Chunxiao, Huang, Weixi, Wang, Lili

“…Linear transient growth of optimal perturbations in particle-laden turbulent channel flow is investigated in this work. The problem is formulated in the…”
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Combined EGFR/MET or EGFR/HSP90 Inhibition Is Effective in the Treatment of Lung Cancers Codriven by Mutant EGFR Containing T790M and MET by LU XU, KIKUCHI, Eiki, SHIMAMURA, Takeshi, WONG, Kwok-Kin, CHUNXIAO XU, EBI, Hiromichi, ERCAN, Dalia, CHENG, Katherine A, PADERA, Robert, ENGELMAN, Jeffrey A, JÄNNE, Pasi A, SHAPIRO, Geoffrey I

“…Tyrosine kinase inhibitors (TKI) that target the EGF receptor (EGFR) are effective in most non-small cell lung carcinoma (NSCLC) patients whose tumors harbor…”
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The Relationship between Low-Sodium Salt Intake and Both Blood Pressure Level and Hypertension in Chinese Residents by Wang, Cuicui, Lu, Zilong, Zhang, Jiyu, Chen, Xiaorong, Xu, Jianwei, Zhang, Bingyin, Dong, Jing, Ren, Jie, Xu, Chunxiao, Gao, Congcong, Guo, Xiaolei, Wu, Jing, Ma, Jixiang

“…Compared to common salt, low-sodium salt can reduce blood pressure to varying degrees. However, the exact dosage relationship remains unclear. We aimed to…”
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Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi‐stage genome‐wide association study by Zhu, Yimin, Zhang, Dandan, Zhou, Dan, Li, Zhenli, Li, Zhiqiang, Fang, Le, Yang, Min, Shan, Zhongyan, Li, Hong, Chen, Jianhua, Zhou, Xianghai, Ye, Wei, Yu, Senhai, Li, Huabin, Cai, Libin, Liu, Chengguo, Zhang, Jie, Wang, Lixin, Lai, Yaxin, Ruan, Liansheng, Sun, Zhanhang, Zhang, Shuai, Wang, Hao, Liu, Yi, Xu, Yuyang, Ling, Jie, Xu, Chunxiao, Zhang, Yan, Lv, Duo, Yuan, Zheping, Zhang, Jing, Zhang, Yingqi, Shi, Yongyong, Lai, Maode

“…Metabolic syndrome (MetS), a cluster of metabolic disturbances that increase the risk for cardiovascular disease and diabetes, was because of genetic…”
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An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer by To, Ciric, Beyett, Tyler S, Jang, Jaebong, Feng, William W, Bahcall, Magda, Haikala, Heidi M, Shin, Bo H, Heppner, David E, Rana, Jaimin K, Leeper, Brittaney A, Soroko, Kara M, Poitras, Michael J, Gokhale, Prafulla C, Kobayashi, Yoshihisa, Wahid, Kamal, Kurppa, Kari J, Gero, Thomas W, Cameron, Michael D, Ogino, Atsuko, Mushajiang, Mierzhati, Xu, Chunxiao, Zhang, Yanxi, Scott, David A, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A

“…Epidermal growth factor receptor (EGFR) therapy using small-molecule tyrosine kinase inhibitors (TKIs) is initially efficacious in patients with EGFR-mutant…”
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