Search Results - "Xiu, Yuwen"
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Incidence, mortality, and economic burden of myasthenia gravis in China: A nationwide population-based study
Published in The Lancet regional health. Western Pacific (01-12-2020)“…Myasthenia gravis (MG) is the most common primary disorder of neuromuscular transmission, but the incidence of MG in China is unknown. We conducted the first…”
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Incidence of Guillain-Barré syndrome (GBS) in China: A national population-based study
Published in The Lancet regional health. Western Pacific (01-01-2022)“…Guillain-Barré syndrome (GBS) is the most prevalent acute autoimmune polyneuropathy, however, the incidence of GBS across China remains undetermined. We…”
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Cortical Thinning and Ventricle Enlargement in Neuromyelitis Optica Spectrum Disorders
Published in Frontiers in neurology (27-08-2020)“…Background: In neuromyelitis optica spectrum disorders (NMOSDs), inflammation is not the sole driver of accumulation of disability; neurodegeneration is…”
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T-Lymphocyte Interactions with the Neurovascular Unit: Implications in Intracerebral Hemorrhage
Published in Cells (Basel, Switzerland) (24-06-2022)“…In the pathophysiology of hemorrhagic stroke, the perturbation of the neurovascular unit (NVU), a functional group of the microvascular and brain intrinsic…”
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The N-terminus of Spt16 anchors FACT to MCM2-7 for parental histone recycling
Published in Nucleic acids research (27-11-2023)“…Parental histone recycling is vital for maintaining chromatin-based epigenetic information during replication, yet its underlying mechanisms remain unclear…”
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The Roles of Mitochondrial Folate Metabolism in Supporting Mitochondrial DNA Synthesis, Oxidative Phosphorylation, and Cellular Function
Published in Current developments in nutrition (01-10-2020)“…Folate-mediated one-carbon metabolism (FOCM) is compartmentalized within human cells to the cytosol, nucleus, and mitochondria. The recent identifications of…”
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The Roles of Mitochondrial Folate Metabolism in Supporting Mitochondrial DNA Synthesis, Oxidative Phosphorylation, and Cellular Function
Published in Current developments in nutrition (01-10-2020)“…Folate-mediated one-carbon metabolism (FOCM) is compartmentalized within human cells to the cytosol, nucleus, and mitochondria. The recent identifications of…”
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Abstract WMP74: Inhibition of T Cell Receptor Activation Improves Neurological Outcomes After Intracerebral Hemorrhage
Published in Stroke (1970) (01-02-2024)“…Abstract only Purpose: We previously reported that activated T cells accumulate in the perihematomal regions after Intracerebral hemorrhage (ICH) and aggravate…”
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Abstract WP142: T Cells Aggravate Intracerebral Hemorrhage Injury
Published in Stroke (1970) (01-02-2022)“…Intracerebral hemorrhage (ICH), a devastating form of stroke, has a mortality of 40% and no available treatment. Inflammation contributes to the genesis and…”
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Reduced Methionine Synthase (Mtr) Expression, a Model of Vitamin B12 Deficiency, Leads to Uracil Accumulation in Mitochondrial and Nuclear DNA
Published in Current developments in nutrition (01-06-2021)“…Integrity of both nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) is affected by nutritional and environmental factors. Folate and B12 are water-soluble…”
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APOE from patient-derived astrocytic extracellular vesicles alleviates neuromyelitis optica spectrum disorder in a mouse model
Published in Science translational medicine (28-02-2024)“…Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy of the central nervous system, mediated by antibodies against aquaporin-4 water…”
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Tracing the path of disruption: 13C isotope applications in traumatic brain injury‐induced metabolic dysfunction
Published in CNS neuroscience & therapeutics (01-03-2024)“…Cerebral metabolic dysfunction is a critical pathological hallmark observed in the aftermath of traumatic brain injury (TBI), as extensively documented in…”
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Reduced Shmt2 Expression Impairs Mitochondrial Folate Accumulation and Respiration, and Leads to Uracil Accumulation in Mouse Mitochondrial DNA
Published in The Journal of nutrition (01-10-2021)“…Adequate cellular thymidylate (dTMP) pools are essential for preservation of nuclear and mitochondrial genome stability. Previous studies have indicated that…”
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CD4 + T cells aggravate hemorrhagic brain injury
Published in Science advances (09-06-2023)“…Leukocyte infiltration accelerates brain injury following intracerebral hemorrhage (ICH). Yet, the involvement of T lymphocytes in this process has not been…”
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Tracing the path of disruption: 13 C isotope applications in traumatic brain injury-induced metabolic dysfunction
Published in CNS neuroscience & therapeutics (01-03-2024)“…Cerebral metabolic dysfunction is a critical pathological hallmark observed in the aftermath of traumatic brain injury (TBI), as extensively documented in…”
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Intravenous immunoglobulin for acute attacks in neuromyelitis optica spectrum disorders (NMOSD)
Published in Multiple sclerosis and related disorders (01-09-2020)“…•IVIG is not recommended as a first-line option for acute attack in NMOSD.•HD-S combined IVIG maybe superiority to HD-S in patients with high onset EDSS…”
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Incidence and Mortality of Acute Disseminated Encephalomyelitis in China: A Nationwide Population-Based Study
Published in Neuroscience bulletin (01-06-2021)Get full text
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Reduced methionine synthase expression results in uracil accumulation in mitochondrial DNA and impaired oxidative capacity
Published in PNAS nexus (01-04-2023)“…Adequate thymidylate [deoxythymidine monophosphate (dTMP) or the "T" base in DNA] levels are essential for stability of mitochondrial DNA (mtDNA) and nuclear…”
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