Search Results - "Xiong, YongMin"

An eQTL variant of ALDH1A2 is associated with Kashin-Beck disease in Chinese population by Zhang, Di, Li, Qiang, Zhang, Dandan, Yang, Xiaoli, Wang, Chen, Zhang, Rongqiang, Yang, Xuena, Li, Zhaofang, Xiong, Yongmin

“…Introduction The aims of the study were to investigate the relationship between aldehyde dehydrogenase 1 family member A2 ( ALDH1A2 ) and Kashin-Beck disease…”
Get full text

Dysregulation of Transcription Profile of Selenoprotein in Patients with Kashin-Beck Disease and Its Effect on Se Deficiency–Induced Chondrocyte Apoptosis by Yang, XiaoLi, Li, ZhaoFang, Zhang, RongQiang, Zhang, Di, Xiong, YongMin, Wang, Chen, Yang, XueNa, Li, Qiang

“…Kashin-Beck disease (KBD) is a chronic, degenerative osteoarthropathy related to selenium (Se) deficiency. Se participates in the synthesis of selenoprotein in…”
Get full text

Analysis of gene expression and methylation datasets identified ADAMTS9, FKBP5, and PFKBF3 as biomarkers for osteoarthritis by Li, ZhaoFang, Zhang, RongQiang, Yang, XiaoLi, Zhang, DanDan, Li, BaoRong, Zhang, Di, Li, Qiang, Xiong, YongMin

“…Background: Osteoarthritis (OA) is a kind of chronic osteoarthropathy and degenerative joint disease. Epigenetic regulation in the gene expression dynamics has…”
Get full text

Crosstalk between CpG Methylation and Polymorphisms (CpG-SNPs) in the Promotor Region of DIO2 in Kashin-Beck Disease by Zhang, Rong-Qiang, Zhang, Dan-Dan, Zhang, Di, Yang, Xiao-Li, Li, Qiang, Wang, Chen, Yang, Xue-Na, Xiong, Yong-Min

“…Objective This study was designed to determine the methylation profile of four CpGs and the genotypes of two CpG-SNPs located in promoter region of in patients…”
Get more information

Identification of differentially expressed and methylated genes associated with rheumatoid arthritis based on network by Zhang, Di, Li, ZhaoFang, Zhang, RongQiang, Yang, XiaoLi, Zhang, DanDan, Li, Qiang, Wang, Chen, Yang, Xuena, Xiong, YongMin

“…Rheumatoid arthritis (RA) is a multi-systemic inflammatory autoimmune disease involving peripheral joints, and the pathogenesis is not clear. Studies showed…”
Get full text

Dystrophin glycoprotein complex-associated Gβγ subunits activate phosphatidylinositol-3-kinase/Akt signaling in skeletal muscle in a laminin-dependent manner by Xiong, Yongmin, Zhou, YanWen, Jarrett, Harry W.

“…Previously, we showed that laminin‐binding to the dystrophin glycoprotein complex (DGC) of skeletal muscle causes a heterotrimeric G‐protein (Gαβγ) to bind,…”
Get full text

Epidemic pattern of hand-foot-and-mouth disease in Xi'an, China from 2008 through 2015 by Liu, JiFeng, Xiang, XiaoMei, Pu, ZhongShu, Long, Yong, Xiao, Dan, Zhang, WeiLu, Li, Qian, Li, XiTong, Li, SiYao, Shao, ZhongJun, Yang, XiaoLi, Xiong, YongMin

“…Hand, foot and mouth disease (HFMD) is an infectious disease caused by enteroviruses that has a severely impair for those high incidence countries such as…”
Get full text

Selenium increases expression of HSP70 and antioxidant enzymes to lessen oxidative damage in Fincoal-type fluorosis by Chen, Qun, Wang, Zhilun, Xiong, Yongmin, Xue, Wanli, Kao, Xibin, Gao, Yan, Muhammad, Nawaz, Song, Daiqin

“…Fincoal type fluorosis has only been reported from China, but its pathogenesis is unclear. Many people believe that fluorosis is associated with oxidative…”
Get full text

Comparative study of p38 MAPK signal transduction pathway of peripheral blood mononuclear cells from patients with coal-combustion-type fluorosis with and without high hair selenium levels by Chen, Qun, Wang, Zhilun, Xiong, Yongmin, Zou, Xiuzhen, Liu, Zhengwen

“…Coal-combustion-type fluorosis has only been reported in China and its pathogenesis has not been fully understood. Fluoride causes chronic toxic effects and…”
Get full text

Selenoprotein P gene r25191g/a polymorphism and quantification of selenoprotein P mRNA level in patients with Kashin-Beck disease by Sun, Wenyan, Wang, Xin, Zou, Xiuzhen, Song, Ruixia, Du, Xiaohong, Hu, Jun, Xiong, Yongmin

“…Kashin-Beck disease (KBD) is an endemic and deformable osteoarthrosis. Epidemiological study has revealed that lower Se level is the principal environmental…”
Get full text

SNP-induced apoptosis may be mediated with caspase inhibitor by JNK signaling pathways in rabbit articular chondrocytes by Chen, Qun, Gao, Yan, Kao, XiBin, Chen, JingHong, Xue, WanLi, Xiong, YongMin, Wang, ZhiLun

“…NO plays an important role in cartilage destruction by inducing apoptosis of chondrocytes. Here we investigated the role of c-Jun N-terminal kinase (JNK)…”
Get full text

No Association between Estrogen Receptor-Β Rs4986938 and Cancer Risk: A Systematic Review and Meta-Analysis by Li, Zhaofang, Yang, Xiaoli, Zhang, Rongqiang, Zhang, Dandan, Li, Baorong, Zhang, Di, Li, Qiang, Xiong, Yongmin

“…The association between estrogen receptor-β (ESR2) rs4986938 polymorphism and the risk of various types of cancer have been investigated in previous studies…”
Get full text

The Study on Polymorphism of TrxR and Nrf2/HO-1 Signaling Pathway in Kaschin-Beck Disease by Li, Yuanyuan, Mo, Xiaoyan, Xiong, Yongmin

“…Kaschin-Beck disease (KBD) is an endemic, chronic, and degenerative osteoarthropathy, which seriously impairs the quality of patients’ life. We detected the…”
Get full text

Mechanism of DNA methylation-mediated downregulation of O6-methylguanine-DNA methyltransferase in cartilage injury of Kashin–Beck disease by Zhang, Dandan, Zhang, Di, Wang, Chen, Zhang, Rongqiang, Li, Qiang, Xiong, Yongmin

“…OBJECTIVEKashin-Beck disease (KBD) is an endemic osteoarthropathy, in which excessive apoptosis of chondrocytes occurs. O6-methylguanine-DNA methyltransferase…”
Get full text

Adenosine A2B receptor stimulates angiogenesis by inducing VEGF and eNOS in human microvascular endothelial cells by Du, Xiaolong, Ou, Xuehai, Song, Tao, Zhang, Wentao, Cong, Fei, Zhang, Shihui, Xiong, Yongmin

“…Angiogenesis is critical to wound repair due to its role in providing oxygen and nutrients that are required to support the growth and function of reparative…”
Get full text

Downregulated Expression and Hypermethylation of SIRT1 in Patients with Kashin-Beck Disease-Mediated Chondrocyte Apoptosis May Potentially Be Ameliorated by Selenium Supplement by Yang, Xiaoli, Han, Lixin, Zhang, Di, Xu, Cuixiang, Jin, Zhankui, Xiong, Yongmin

“…This study aims to elucidate the role of silent information regulator 2 homologue 1 (SIRT1) in cartilage damage in Kashin-Beck disease (KBD) by exploring the…”
Get full text

The Role of Selenium-Mediated Notch/Hes1 Signaling Pathway in Kashin–Beck Disease Patients and Cartilage Injury Models by Zhang, Di, Zhang, Dandan, Yang, Xiaoli, Li, Qiang, Zhang, Rongqiang, Xiong, YongMin

“…Kashin–Beck disease (KBD) is a nutrition-related osteoarthropathy, and selenium (Se) deficiency is an environmental risk factor for KBD. Notch/Hes1 signaling…”
Get full text

Gene and prognostic value of N6-methyladenosine (m 6 A) modification regulatory factors in lung adenocarcinoma by Zhang, Di, Zhang, DanDan, Wang, Chen, Yang, XiaoLi, Zhang, RongQiang, Li, Qiang, Xiong, YongMin

“…Lung cancer is the leading cause of death worldwide, and its incidence continues to increase. The treatment of lung cancer is related to the subtypes and…”
Get full text

The CD25+/CD4+ T cell ratio and levels of CII, CIX and CXI antibodies in serum may serve as biomarkers of pristane-induced arthritis in rats and Rheumatoid Arthritis in humans by Chen, Qun, Zhang, Xiaotian, Xiong, Yongmin, Chen, Chen, Lv, Shemin

“…Collagen antibodies in serum are involved in the pathogenesis of Rheumatoid Arthritis (RA). The objective of this study was to identify the subtype of collagen…”
Get full text

Pathway-based network analyses and candidate genes associated with Kashin-Beck disease by Zhang, Rongqiang, Guo, Hao, Yang, Xiaoli, Zhang, Dandan, Li, Baorong, Li, Zhaofang, Xiong, Yongmin

“…To perform a comprehensive analysis focusing on the biological functions and interactions of Kashin-Beck disease (KBD)-related genes to provide information…”
Get full text